Constitutive synthesis of interleukin-3 by leukaemia cell line WEHI-3B is due to retroviral insertion near the gene.
about
Evi27 encodes a novel membrane protein with homology to the IL17 receptorEvidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic functionFunctional murine interleukin 6 receptor with the intracisternal A particle gene product at its cytoplasmic domain. Its possible role in plasmacytomagenesisMicroarray-based global mapping of integration sites for the retrotransposon, intracisternal A-particle, in the mouse genomeAbrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATsIsolation of genes specifically expressed in flat revertant cells derived from activated ras-transformed NIH 3T3 cells by treatment with azatyrosineIdentification and characterization of novel human endogenous retroviral sequences prefentially expressed in undifferentiated embryonal carcinoma cellsAn indicator gene to demonstrate intracellular transposition of defective retroviruses.Specific inhibition of interleukin 3 bioactivity by a monoclonal antibody reactive with hematopoietic progenitor cells.A non-ATP-competitive inhibitor of BCR-ABL overrides imatinib resistance.Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia.Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL.Expression of the LIM-homeobox gene LH2 generates immortalized steel factor-dependent multipotent hematopoietic precursors.In vivo transformation of factor-dependent hemopoietic cells: role of intracisternal A-particle transposition for growth factor gene activationEstablishment of an interleukin-5-dependent subclone from an interleukin-3-dependent murine hemopoietic progenitor cell line, LyD9, and its malignant transformation by autocrine secretion of interleukin-5Close genetic and physical linkage between the murine haemopoietic growth factor genes GM-CSF and Multi-CSF (IL3).Cyclosporin A promotes translational silencing of autocrine interleukin-3 via ribosome-associated deadenylation.Conditional immortalization of mouse myelomonocytic, megakaryocytic and mast cell progenitors by the Hox-2.4 homeobox gene.Autocrine stimulation by erythropoietin and autonomous growth of human erythroid leukemic cells in vitroExpression of ras oncogenes in cultured human cells alters the transcriptional and posttranscriptional regulation of cytokine genes.Autocrine stimulation after transfer of the granulocyte/macrophage colony-stimulating factor gene and autonomous growth are distinct but interdependent steps in the oncogenic pathwayAutonomous expression of RTVL-H endogenous retroviruslike elements in human cells.The lethal yellow allele-associated provirus results in the production of chimeric viral-host RNAs.Splicing of a human endogenous retrovirus to a novel phospholipase A2 related geneStructural analysis of type II variants within the mouse intracisternal A-particle sequence family.Nucleotide sequence of the intracisternal A-particle genome inserted 5' to the interleukin-3 gene of the leukemia cell line WEHI-3B.The role of HuR in the post-transcriptional regulation of interleukin-3 in T cells.Homologous recombination between the LTRs of a human retrovirus-like element causes a 5-kb deletion in two siblings.Expression of Hox-2.4 homeobox gene directed by proviral insertion in a myeloid leukemia.Characterization of amplified intracisternal A-particle elements encoding integrase.Functional heterogeneity of a large family of human LTR-like promoters and enhancers.Molecular mechanisms associated with the regulation of apoptosis by the two alternatively spliced products of c-MybDNA rearrangement of a homeobox gene in myeloid leukaemic cells.Animal models of acute myelogenous leukaemia - development, application and future perspectives.Retroviral activation of interleukin 2 gene in a gibbon ape T cell lymphoma line.Suppressible and nonsuppressible autocrine mast cell tumors are distinguished by insertion of an endogenous retroviral element (IAP) into the interleukin 3 gene.Identification of a new common provirus integration site in gross passage A murine leukemia virus-induced mouse thymoma DNA.C/EBP epsilon mediates myeloid differentiation and is regulated by the CCAAT displacement protein (CDP/cut).The zinc finger transcription factor Egr-1 potentiates macrophage differentiation of hematopoietic cellsILs-3, 6 and 11 increase, but ILs-10 and 24 decrease stemness of human prostate cancer cells in vitro.
P2860
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P2860
Constitutive synthesis of interleukin-3 by leukaemia cell line WEHI-3B is due to retroviral insertion near the gene.
description
1985 nî lūn-bûn
@nan
1985 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1985 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
name
Constitutive synthesis of inte ...... viral insertion near the gene.
@ast
Constitutive synthesis of inte ...... viral insertion near the gene.
@en
Constitutive synthesis of inte ...... viral insertion near the gene.
@nl
type
label
Constitutive synthesis of inte ...... viral insertion near the gene.
@ast
Constitutive synthesis of inte ...... viral insertion near the gene.
@en
Constitutive synthesis of inte ...... viral insertion near the gene.
@nl
prefLabel
Constitutive synthesis of inte ...... viral insertion near the gene.
@ast
Constitutive synthesis of inte ...... viral insertion near the gene.
@en
Constitutive synthesis of inte ...... viral insertion near the gene.
@nl
P2093
P921
P356
P1433
P1476
Constitutive synthesis of inte ...... viral insertion near the gene.
@en
P2093
P2888
P304
P356
10.1038/317255A0
P407
P577
1985-09-01T00:00:00Z
P6179
1006263293