High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines.
about
Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repairDeficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joiningRecombinational DNA Repair in Cancer and Normal Cells: The Challenge of Functional AnalysisHomologous Recombination and Its Role in CarcinogenesisTargeting ATM-deficient CLL through interference with DNA repair pathwaysRadiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-AblATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells.Replication protein A is sequentially phosphorylated during meiosis.Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene.DNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe.Manipulating the mammalian genome by homologous recombinationTissue-specific differences in the accumulation of sequence rearrangements with age.The yeast TEL1 gene partially substitutes for human ATM in suppressing hyperrecombination, radiation-induced apoptosis and telomere shortening in A-T cells.The role of Alu repeat clusters as mediators of recurrent chromosomal aberrations in tumors.ATM mutations in sporadic lymphoid tumours.Repair of radiation damage to DNA.Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase.Modification of non-conservative double-strand break (DSB) rejoining activity after the induction of cisplatin resistance in human tumour cells.Exploiting synthetic lethal interactions for targeted cancer therapy.Vanillins--a novel family of DNA-PK inhibitors.The controlling role of ATM in homologous recombinational repair of DNA damageDNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM.Disruption of the BLM gene in ATM-null DT40 cells does not exacerbate either phenotype.Double strand break repair by homologous recombination is regulated by cell cycle-independent signaling via ATM in human glioma cells.ATM's leucine-rich domain and adjacent sequences are essential for ATM to regulate the DNA damage response.Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53.Variations in ATM protein expression during normal lymphoid differentiation and among B-cell-derived neoplasias.Differential level of DSB repair fidelity effected by nuclear protein extracts derived from radiosensitive and radioresistant human tumour cells.DNA-PKcs and ATM co-regulate DNA double-strand break repairLow dose X-radiation adaptive response in spleen and prostate of Atm knockout heterozygous mice.
P2860
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P2860
High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines.
description
1996 nî lūn-bûn
@nan
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines.
@ast
High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines.
@en
High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines.
@nl
type
label
High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines.
@ast
High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines.
@en
High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines.
@nl
prefLabel
High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines.
@ast
High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines.
@en
High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines.
@nl
P2093
P2860
P356
P1476
High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines.
@en
P2093
P2860
P304
P356
10.1074/JBC.271.8.4497
P407
P577
1996-02-01T00:00:00Z