Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques. - Wikidata - awgldk - TriplyDB

Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques.

Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques.

http://www.wikidata.org/entity/Q34382386

about

Emerging concepts in the immunopathogenesis of AIDS Glucose Metabolism in T Cells and Monocytes: New Perspectives in HIV Pathogenesis Immunovirological parameters and cytokines in HIV infection Induction of intestinal immunity by mucosal vaccines as a means of controlling HIV infection The role of interleukin-21 in HIV infection A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21 Immune activation and paediatric HIV-1 disease outcome Long-term programming of antigen-specific immunity from gene expression signatures in the PBMC of rhesus macaques immunized with an SIV DNA vaccine Increased sensitivity of CD4+ T-effector cells to CD4+CD25+ Treg suppression compensates for reduced Treg number in asymptomatic HIV-1 infection Role of Occult and Post-acute Phase Replication in Protective Immunity Induced with a Novel Live Attenuated SIV Vaccine CD4 T cell subsets in the mucosa are CD28+Ki-67-HLA-DR-CD69+ but show differential infection based on alpha4beta7 receptor expression during acute SIV infection.Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections.Modulation of gut-specific mechanisms by chronic δ(9)-tetrahydrocannabinol administration in male rhesus macaques infected with simian immunodeficiency virus: a systems biology analysis.Human Beta Defensin 2 Selectively Inhibits HIV-1 in Highly Permissive CCR6⁺CD4⁺ T Cells.The loss of CCR6+ and CD161+ CD4+ T-cell homeostasis contributes to disease progression in SIV-infected rhesus macaques.Progressive proximal-to-distal reduction in expression of the tight junction complex in colonic epithelium of virally-suppressed HIV+ individuals.Evidence for polymicrobic flora translocating in peripheral blood of HIV-infected patients with poor immune response to antiretroviral therapy.Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection Th17 cytokines in mucosal immunity and inflammation.Immune dysregulation in human immunodeficiency virus infection: know it, fix it, prevent it?Nonprogressive and progressive primate immunodeficiency lentivirus infections.Innate immune recognition and activation during HIV infection.Mucosal immunity in human and simian immunodeficiency lentivirus infections Plasmacytoid dendritic cells mediate synergistic effects of HIV and lipopolysaccharide on CD27+ IgD- memory B cell apoptosis Loss and dysregulation of Th17 cells during HIV infection.Mechanisms underlying γδ T-cell subset perturbations in SIV-infected Asian rhesus macaques.Reconstitution of intestinal CD4 and Th17 T cells in antiretroviral therapy suppressed HIV-infected subjects: implication for residual immune activation from the results of a clinical trial.Th17 and regulatory T cells: implications for AIDS pathogenesis Blunted IL17/IL22 and pro-inflammatory cytokine responses in the genital tract and blood of HIV-exposed, seronegative female sex workers in Kenya Th17 Cells Coordinate with Th22 Cells in Maintaining Homeostasis of Intestinal Tissues and both are Depleted in SIV-Infected Macaques.Immunopathogenesis of asymptomatic chronic HIV Infection: the calm before the storm.HIV-associated chronic immune activation.Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation Interaction between endogenous bacterial flora and latent HIV infection.Relationships between IL-17(+) subsets, Tregs and pDCs that distinguish among SIV infected elite controllers, low, medium and high viral load rhesus macaques.HIV and the Gastrointestinal Tract.CD4+ T cells, including Th17 and cycling subsets, are intact in the gut mucosa of HIV-1-infected long-term nonprogressors

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Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques.

http://www.wikidata.org/entity/Q34382386

description

2008 nî lūn-bûn

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2008 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2008 թվականի մայիսին հրատարակված գիտական հոդված

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2008年の論文

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D C Douek

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D Venzon

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P2860

Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

Transforming growth factor-beta induces development of the T(H)17 lineage

Cutting edge: interleukin 17 signals through a heteromeric receptor complex

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

Interleukin-17 family members and inflammation

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

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10.1038/MI.2008.14

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Simian immunodeficiency virus

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2997489

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