Reactivity of anticancer metallodrugs with serum proteins: new insights from size exclusion chromatography-ICP-MS and ESI-MS
about
Competitive binding of Fe3+, Cr3+, and Ni2+ to transferrinFAB, ESI and MALDI Mass Spectrometric methods in the study of metallo-drugs and their biomolecular interactions.The interaction of platinum-based drugs with native biologically relevant proteins.Systemic administration of 3-bromopyruvate reveals its interaction with serum proteins in a rat model.New ruthenium(II) arene complexes of anthracenyl-appended diazacycloalkanes: effect of ligand intercalation and hydrophobicity on DNA and protein binding and cleavage and cytotoxicity.Comparative in vitro and in vivo pharmacological investigation of platinum(IV) complexes as novel anticancer drug candidates for oral application.Anticancer metallodrug research analytically painting the "omics" picture--current developments and future trends.Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs.Combination of metallomics and proteomics to study the effects of the metallodrug RAPTA-T on human cancer cells.Cellular uptake and subcellular distribution of ruthenium-based metallodrugs under clinical investigation versus cisplatin.Spectroscopic Study of the Interactions of Ruthenium-Ketoconazole Complexes of Known Antiparasitic Activity with Human Serum Albumin and Apotransferrin.Metallomics in drug development: characterization of a liposomal cisplatin drug formulation in human plasma by CE-ICP-MS.Study on the interaction between a water-soluble dinuclear nickel complex and bovine serum albumin by spectroscopic techniques.N-acetyl-L-cysteine modulates the metabolism of cis-platin in human plasma in vitro.Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action† †Electronic supplementary information (ESI) available: Experimental, crystallographic, biological and mass spectrometric data, full list of prTarget profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action.Synthesis and crystal structures of novel copper(II) complexes with glycine and substituted phenanthrolines: reactivity towards DNA/BSA and in vitro cytotoxic and antimicrobial evaluation.Protein binding by dinuclear polypyridyl ruthenium(II) complexes and the effect of cucurbit[10]uril encapsulation.The impact of whole human blood on the kinetic inertness of platinum(iv) prodrugs - an HPLC-ICP-MS study.Serum-binding properties of isosteric ruthenium and osmium anticancer agents elucidated by SEC-ICP-MSMetal Species in Biology: Bottom-Up and Top-Down LC Approaches in Applied Toxicological Research
P2860
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P2860
Reactivity of anticancer metallodrugs with serum proteins: new insights from size exclusion chromatography-ICP-MS and ESI-MS
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Reactivity of anticancer metal ...... romatography-ICP-MS and ESI-MS
@ast
Reactivity of anticancer metal ...... romatography-ICP-MS and ESI-MS
@en
Reactivity of anticancer metal ...... romatography-ICP-MS and ESI-MS
@nl
type
label
Reactivity of anticancer metal ...... romatography-ICP-MS and ESI-MS
@ast
Reactivity of anticancer metal ...... romatography-ICP-MS and ESI-MS
@en
Reactivity of anticancer metal ...... romatography-ICP-MS and ESI-MS
@nl
prefLabel
Reactivity of anticancer metal ...... romatography-ICP-MS and ESI-MS
@ast
Reactivity of anticancer metal ...... romatography-ICP-MS and ESI-MS
@en
Reactivity of anticancer metal ...... romatography-ICP-MS and ESI-MS
@nl
P2093
P2860
P50
P356
P1476
Reactivity of anticancer metal ...... romatography-ICP-MS and ESI-MS
@en
P2093
Lisa Elviri
Mattia Terenghi
Ryszard Lobinski
P2860
P304
P356
10.1039/B922701F
P577
2010-03-01T00:00:00Z