GR127935: a potent and selective 5-HT1D receptor antagonist.
about
F15063, a potential antipsychotic with D2/D3 antagonist, 5-HT 1A agonist and D4 partial agonist properties. I. In vitro receptor affinity and efficacy profileSumatriptan elicits both constriction and dilation in human and bovine brain intracortical arteriolesEvidence for 5-HT(1B/1D) and 5-HT(2A) receptors mediating constriction of the canine internal carotid circulationPharmacological diversity between native human 5-HT1B and 5-HT1D receptors sited on different neurons and involved in different functionsPharmacological evidence for the 5-HT7 receptor mediating smooth muscle relaxation in canine cerebral arteriesPharmacological profile of the 5-HT-induced inhibition of cardioaccelerator sympathetic outflow in pithed rats: correlation with 5-HT1 and putative 5-ht5A/5B receptors.The antimigraine 5-HT 1B/1D receptor agonists, sumatriptan, zolmitriptan and dihydroergotamine, attenuate pain-related behaviour in a rat model of trigeminal neuropathic pain.Therapeutic potential of serotonin antagonists in depressive disorders.Detection of phospholipidosis induction: a cell-based assay in high-throughput and high-content format.5-HT1A and beyond: the role of serotonin and its receptors in depression and the antidepressant response.Canine external carotid vasoconstriction to methysergide, ergotamine and dihydroergotamine: role of 5-HT1B/1D receptors and alpha2-adrenoceptors.Functional characterization and m-RNA expression of 5-HT receptors mediating contraction in human umbilical arteryNo contractile effect for 5-HT1D and 5-HT1F receptor agonists in human and bovine cerebral arteries: similarity with human coronary artery.Molecular cloning, sequence analysis and pharmacological properties of the porcine 5-HT(1D) receptorKetanserin-sensitive depressant actions of 5-HT receptor agonists in the neonatal rat spinal cord.Experimental migraine models and their relevance in migraine therapy.Role of 5-hydroxytryptamine 1B (5-HT1B) receptors in the regulation of ethanol intake in rodents.Pharmacological evidence that alpha1-and alpha2-adrenoceptors mediate vasoconstriction of carotid arteriovenous anastomoses in anaesthetized pigs.Activation of 5-HT1B and 5-HT1D receptors in the rat nucleus tractus solitarius: opposing action on neurones that receive an excitatory vagal C-fibre afferent input.On the role of 5-HT1B/1D receptors in modulating transmission in a spinal reflex pathway in the decerebrated rabbit.Multiple microvascular and astroglial 5-hydroxytryptamine receptor subtypes in human brain: molecular and pharmacologic characterization.Mechanisms involved in the regulation of bovine pulmonary vascular tone by the 5-HT1B receptor.Investigation of the role of 5-HT1B and 5-HT1D receptors in the sumatriptan-induced constriction of porcine carotid arteriovenous anastomoses.Serotonin-induced increases in adult cell proliferation and neurogenesis are mediated through different and common 5-HT receptor subtypes in the dentate gyrus and the subventricular zone.Functional Characterization of 5-HT1B Receptor Drugs in Nonhuman Primates Using Simultaneous PET-MR.NXN-188, a selective nNOS inhibitor and a 5-HT1B/1D receptor agonist, inhibits CGRP release in preclinical migraine models
P2860
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P2860
GR127935: a potent and selective 5-HT1D receptor antagonist.
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
GR127935: a potent and selective 5-HT1D receptor antagonist.
@ast
GR127935: a potent and selective 5-HT1D receptor antagonist.
@en
GR127935: a potent and selective 5-HT1D receptor antagonist.
@nl
type
label
GR127935: a potent and selective 5-HT1D receptor antagonist.
@ast
GR127935: a potent and selective 5-HT1D receptor antagonist.
@en
GR127935: a potent and selective 5-HT1D receptor antagonist.
@nl
prefLabel
GR127935: a potent and selective 5-HT1D receptor antagonist.
@ast
GR127935: a potent and selective 5-HT1D receptor antagonist.
@en
GR127935: a potent and selective 5-HT1D receptor antagonist.
@nl
P2093
P1476
GR127935: a potent and selective 5-HT1D receptor antagonist.
@en
P2093
Beattie DT
Starkey SJ
P304
P356
10.1016/0166-4328(96)00089-7
P407
P577
1996-01-01T00:00:00Z