Towards a structure for a TSG-6.hyaluronan complex by modeling and NMR spectroscopy: insights into other members of the link module superfamily.
about
Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphismTSG-6 binds via its CUB_C domain to the cell-binding domain of fibronectin and increases fibronectin matrix assemblyHomodimerization of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-labile Disulfide Is Critical for Hyaluronan Binding in Lymphatic EndotheliumNuclear Magnetic Resonance Insight into the Multiple Glycosaminoglycan Binding Modes of the Link Module from Human TSG-6Metal Ion-dependent Heavy Chain Transfer Activity of TSG-6 Mediates Assembly of the Cumulus-Oocyte Matrix.Administration of TSG-6 improves memory after traumatic brain injury in mice.Fourier transform mass spectrometry to monitor hyaluronan-protein interactions: use of hydrogen/deuterium amide exchangeThe N-terminal module of thrombospondin-1 interacts with the link domain of TSG-6 and enhances its covalent association with the heavy chains of inter-alpha-trypsin inhibitor.Incorporation of pentraxin 3 into hyaluronan matrices is tightly regulated and promotes matrix cross-linking.Expression, processing, and glycosaminoglycan binding activity of the recombinant human 315-kDa hyaluronic acid receptor for endocytosis (HARE).The inflammation-associated protein TSG-6 cross-links hyaluronan via hyaluronan-induced TSG-6 oligomers.Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It.TSG-6 protein is crucial for the development of pulmonary hyaluronan deposition, eosinophilia, and airway hyperresponsiveness in a murine model of asthma.Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver.TSG-6 regulates bone remodeling through inhibition of osteoblastogenesis and osteoclast activationThe ligand-binding profile of HARE: hyaluronan and chondroitin sulfates A, C, and D bind to overlapping sites distinct from the sites for heparin, acetylated low-density lipoprotein, dermatan sulfate, and CS-E.G1 Domain of Versican Regulates Hyaluronan Organization and the Phenotype of Cultured Human Dermal Fibroblasts.Cathelicidin antimicrobial peptides inhibit hyaluronan-induced cytokine release and modulate chronic allergic dermatitis.Inter-α-inhibitor impairs TSG-6-induced hyaluronan cross-linking.Antitumor therapy mediated by 5-fluorocytosine and a recombinant fusion protein containing TSG-6 hyaluronan binding domain and yeast cytosine deaminaseA refined model for the TSG-6 link module in complex with hyaluronan: use of defined oligosaccharides to probe structure and function.Carbohydrate-protein interactions: a 3D view by NMR.Hyaluronan binding to link module of TSG-6 and to G1 domain of aggrecan is differently regulated by pH.Provisional matrix: A role for versican and hyaluronan.Chemoenzymatic synthesis with distinct Pasteurella heparosan synthases: monodisperse polymers and unnatural structures.Hyaluronan: the absence of amide-carboxylate hydrogen bonds and the chain conformation in aqueous solution are incompatible with stable secondary and tertiary structure models.Characterization of the interaction between tumor necrosis factor-stimulated gene-6 and heparin: implications for the inhibition of plasmin in extracellular matrix microenvironments.Determining the molecular basis for the pH-dependent interaction between the link module of human TSG-6 and hyaluronan.Single-Molecule Unbinding Forces between the Polysaccharide Hyaluronan and Its Binding Proteins
P2860
Q27644071-D99AFF39-C728-4921-A9C9-EED231A3EBF9Q28119026-3758628C-2137-4732-8779-70BB829A88FAQ28593262-C7E3D549-5AE0-41D7-A75E-A13364B56078Q28821408-8AE87200-9535-4C17-9373-2D141CB76B59Q30380284-B3AA1E01-9208-41F0-89FA-1FEB995637A5Q30548200-FCDD62D3-1D03-44C9-BCF6-D62B0792DC29Q34303919-C1A1E524-918D-481F-96EB-53E4F5BB1CD7Q34313838-1CE1ADA0-004F-45E4-9E2E-A2577C59AE30Q34430984-A36D6EB9-B3BB-4FDC-A989-499F8ABFF8A2Q34587232-7A671798-22E9-4795-B16C-A453A7AFE4BBQ35110999-95DDDFDE-B6B3-406B-B572-ABA2B6682DEAQ35899925-FAFAF60E-DC67-4C35-9D33-0D15E2010543Q36508659-CF9E31BB-1140-4F3B-B908-EC55A1BC862BQ36775577-0F667E4B-B12E-4E23-B4E1-2944CEFCA8B7Q36871656-805F51A4-C603-4F39-A831-DB5B6128B605Q36922376-491A25D2-ADCF-46BE-8422-6A986DCD02C4Q36954963-1C1C55B3-04C0-4F21-A00F-8A3E6EA9003FQ37127416-B66A9F75-485D-4047-AA89-880B540A4D09Q37226176-B36435C8-468E-4A0A-8FD5-29D9E5BC8A2CQ37251338-C930B8AA-B4C2-472C-8BEB-31E247619C4DQ37608450-021ED268-D247-4BB7-9676-25B3AA524345Q37866236-6050EDF9-4170-47B3-A078-D88840E0A8AAQ38360686-01E8C9A9-45D7-4851-8470-59520234BA74Q39033619-1DF02599-DE2C-4291-981C-F2EFC10CA565Q40194481-2061CD53-9D3E-4EAA-A1F1-5B568AD0E03DQ41673750-ADFC4561-0107-4B06-8718-628D8C087467Q46510509-862BACBD-B605-4864-BB34-54A63B6AFB99Q53577939-D854E558-45B9-4D67-876A-823F7B71D149Q58421487-757D43C5-6948-49C9-A754-EF86D642A310
P2860
Towards a structure for a TSG-6.hyaluronan complex by modeling and NMR spectroscopy: insights into other members of the link module superfamily.
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Towards a structure for a TSG- ...... f the link module superfamily.
@ast
Towards a structure for a TSG- ...... f the link module superfamily.
@en
Towards a structure for a TSG- ...... f the link module superfamily.
@nl
type
label
Towards a structure for a TSG- ...... f the link module superfamily.
@ast
Towards a structure for a TSG- ...... f the link module superfamily.
@en
Towards a structure for a TSG- ...... f the link module superfamily.
@nl
prefLabel
Towards a structure for a TSG- ...... f the link module superfamily.
@ast
Towards a structure for a TSG- ...... f the link module superfamily.
@en
Towards a structure for a TSG- ...... f the link module superfamily.
@nl
P2093
P2860
P356
P1476
Towards a structure for a TSG- ...... of the link module superfamily
@en
P2093
Charles D Blundell
David J Mahoney
Iain D Campbell
Paul L DeAngelis
P2860
P304
18189-18201
P356
10.1074/JBC.M414343200
P407
P577
2005-02-17T00:00:00Z