about
Explaining oscillations and variability in the p53-Mdm2 systemThe Importance of Ubiquitin E3 Ligases, SCF and APC/C, in Human CancersReaction-diffusion systems for spatio-temporal intracellular protein networks: A beginner's guide with two examplesEmerging Non-Canonical Functions and Regulation by p53: p53 and StemnessChemical memory reactions induced bursting dynamics in gene expressionStochasticity of intranuclear biochemical reaction processes controls the final decision of cell fate associated with DNA damageThe pharmacodynamics of the p53-Mdm2 targeting drug Nutlin: the role of gene-switching noiseIdentification and characterization of a novel Mdm2 splice variant acutely induced by the chemotherapeutic agents adriamycin and actinomycin DOscillations and variability in the p53 systemRapid cycling and precocious termination of G1 phase in cells expressing CDK1AF.Fourier analysis and systems identification of the p53 feedback loopOn systems and control approaches to therapeutic gain.Oscillations of the p53-Akt network: implications on cell survival and deathSimple molecular networks that respond optimally to time-periodic stimulation.Comparisons of robustness and sensitivity between cancer and normal cells by microarray dataAdvanced proteomic technologies for cancer biomarker discovery.Modeling the role of p53 pulses in DNA damage- induced cell death decision.Predicted functions of MdmX in fine-tuning the response of p53 to DNA damage.Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cellsStress-specific response of the p53-Mdm2 feedback loopAnalysis and verification of the HMGB1 signaling pathway.A theoretical exploration of birhythmicity in the p53-Mdm2 network.Kinase inhibitors can produce off-target effects and activate linked pathways by retroactivity.A plausible model for the digital response of p53 to DNA damage.Modeling the basal dynamics of p53 system.Communicating oscillatory networks: frequency domain analysis.Coordination between cell cycle progression and cell fate decision by the p53 and E2F1 pathways in response to DNA damage.HIF-2α suppresses p53 to enhance the stemness and regenerative potential of human embryonic stem cells.A two-step mechanism for cell fate decision by coordination of nuclear and mitochondrial p53 activities.The dynamics of stress p53-Mdm2 network regulated by p300 and HDAC1.Mechanisms that enhance sustainability of p53 pulsesLevels of pro-apoptotic regulator Bad and anti-apoptotic regulator Bcl-xL determine the type of the apoptotic logic gate.Computational modeling of mammalian signaling networks.Akt versus p53 in a network of oncogenes and tumor suppressor genes regulating cell survival and death.Stochastic modeling and simulation of the p53-MDM2/MDMX loopGene perturbation and intervention in context-sensitive stochastic Boolean networks.MiR-192-Mediated Positive Feedback Loop Controls the Robustness of Stress-Induced p53 Oscillations in Breast Cancer CellsFeedbacks, Bifurcations, and Cell Fate Decision-Making in the p53 SystemOscillations in the immune system.Cell fate decision mediated by p53 pulses
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Steady states and oscillations in the p53/Mdm2 network.
@ast
Steady states and oscillations in the p53/Mdm2 network.
@en
Steady states and oscillations in the p53/Mdm2 network.
@nl
type
label
Steady states and oscillations in the p53/Mdm2 network.
@ast
Steady states and oscillations in the p53/Mdm2 network.
@en
Steady states and oscillations in the p53/Mdm2 network.
@nl
prefLabel
Steady states and oscillations in the p53/Mdm2 network.
@ast
Steady states and oscillations in the p53/Mdm2 network.
@en
Steady states and oscillations in the p53/Mdm2 network.
@nl
P356
P1433
P1476
Steady states and oscillations in the p53/Mdm2 network
@en
P2093
Andrea Ciliberto
P304
P356
10.4161/CC.4.3.1548
P577
2005-03-18T00:00:00Z