Fibroblast growth factor 21 is regulated by the IRE1α-XBP1 branch of the unfolded protein response and counteracts endoplasmic reticulum stress-induced hepatic steatosis - Wikidata - awgldk - TriplyDB

Fibroblast growth factor 21 is regulated by the IRE1α-XBP1 branch of the unfolded protein response and counteracts endoplasmic reticulum stress-induced hepatic steatosis

Fibroblast growth factor 21 is regulated by the IRE1α-XBP1 branch of the unfolded protein response and counteracts endoplasmic reticulum stress-induced hepatic steatosis

http://www.wikidata.org/entity/Q34396839

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Research Perspectives on the Regulation and Physiological Functions of FGF21 and its Association with NAFLD Metabolic Adaptation in Obesity and Type II Diabetes: Myokines, Adipokines and Hepatokines Whole genome transcript profiling of drug induced steatosis in rats reveals a gene signature predictive of outcome Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity Identification of Sp1 as a Transcription Activator to Regulate Fibroblast Growth Factor 21 Gene Expression.GCN2 is required to increase fibroblast growth factor 21 and maintain hepatic triglyceride homeostasis during asparaginase treatment.Expression and clinical significance of fibroblast growth factor 1 in gastric adenocarcinoma.A muscle-liver-fat signalling axis is essential for central control of adaptive adipose remodelling.Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet β-aminoisobutyric acid attenuates hepatic endoplasmic reticulum stress and glucose/lipid metabolic disturbance in mice with type 2 diabetes Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease Fibroblast Activation Protein Cleaves and Inactivates Fibroblast Growth Factor 21 Hepatic Fatty Acid Oxidation Restrains Systemic Catabolism during Starvation.Hepatic Aryl Hydrocarbon Receptor Attenuates Fibroblast Growth Factor 21 Expression Fibroblast growth factor 21 reflects liver fat accumulation and dysregulation of signalling pathways in the liver of C57BL/6J mice.Growth differentiation factor 15 as a useful biomarker for mitochondrial disorders.Nuclear Receptors Resolve Endoplasmic Reticulum Stress to Improve Hepatic Insulin Resistance.The Effect of Sitagliptin on Lipid Metabolism of Fatty Liver Mice and Related Mechanisms.Endotoxemia-mediated activation of acetyltransferase P300 impairs insulin signaling in obesity.Fibroblast growth factor 21 reverses suppression of adiponectin expression via inhibiting endoplasmic reticulum stress in adipose tissue of obese mice.A Fibroblast Growth Factor 21-Pregnane X Receptor Pathway Downregulates Hepatic CYP3A4 in Nonalcoholic Fatty Liver Disease.Fibroblast growth factor 21 induction by activating transcription factor 4 is regulated through three amino acid response elements in its promoter region.Targeting endoplasmic reticulum stress in liver disease.Increased lipogenesis in spite of upregulated hepatic 5'AMP-activated protein kinase in human non-alcoholic fatty liver.Endoplasmic reticulum proteostasis in hepatic steatosis.FGF21 activates AMPK signaling: impact on metabolic regulation and the aging process.Fructose and NAFLD: The Multifaceted Aspects of Fructose Metabolism.Gastric bypass surgery is protective from high-fat diet-induced non-alcoholic fatty liver disease and hepatic endoplasmic reticulum stress.Dysregulated expression of proteins associated with ER stress, autophagy and apoptosis in tissues from nonalcoholic fatty liver disease Glucagon and Insulin Cooperatively Stimulate Fibroblast Growth Factor 21 Gene Transcription by Increasing the Expression of Activating Transcription Factor 4.Diverse Changes of Circulating Fibroblast Growth Factor 21 Levels in Hepatitis B Virus-Related Diseases.Clinical and genetic characterisation of infantile liver failure syndrome type 1, due to recessive mutations in LARS.Induction of fibroblast growth factor 21 does not require activation of the hepatic X-box binding protein 1 in mice.Endoplasmic reticulum stress in the pathogenesis of fibrotic disease.Hepatocyte-specific deletion of BAP31 promotes SREBP1C activation, promotes hepatic lipid accumulation, and worsens IR in mice.The eIF2-alpha kinase HRI: a potential target beyond the red blood cell.FGF21-induced by carbon monoxide mediates metabolic homeostasis via the PERK/ATF4 pathway.Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease.FGF21 Is an Exocrine Pancreas Secretagogue.Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver.

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P2860

Fibroblast growth factor 21 is regulated by the IRE1α-XBP1 branch of the unfolded protein response and counteracts endoplasmic reticulum stress-induced hepatic steatosis

http://www.wikidata.org/entity/Q34396839

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

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2014年論文

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2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

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2014年论文

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name

Fibroblast growth factor 21 is ...... ress-induced hepatic steatosis

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Fibroblast growth factor 21 is ...... ress-induced hepatic steatosis

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Fibroblast growth factor 21 is ...... ress-induced hepatic steatosis

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type

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Fibroblast growth factor 21 is ...... ress-induced hepatic steatosis

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Fibroblast growth factor 21 is ...... ress-induced hepatic steatosis

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Fibroblast growth factor 21 is ...... ress-induced hepatic steatosis

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Fibroblast growth factor 21 is ...... ress-induced hepatic steatosis

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Fibroblast growth factor 21 is ...... ress-induced hepatic steatosis

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Fibroblast growth factor 21 is ...... ress-induced hepatic steatosis

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JBC.M114.565960

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Journal of Biological Chemistry

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Fibroblast growth factor 21 is ...... ress-induced hepatic steatosis

@en

P2093

Cheng Yan

http://www.w3.org/2001/XMLSchema#string

Hua-ting Li

http://www.w3.org/2001/XMLSchema#string

Jian Zhou

http://www.w3.org/2001/XMLSchema#string

Jing-qi Liu

http://www.w3.org/2001/XMLSchema#string

Liu Yang

http://www.w3.org/2001/XMLSchema#string

Qi-chen Fang

http://www.w3.org/2001/XMLSchema#string

Shan Jiang

http://www.w3.org/2001/XMLSchema#string

Wei-ping Jia

http://www.w3.org/2001/XMLSchema#string

Yang Liu

http://www.w3.org/2001/XMLSchema#string

Yi-ping Deng

http://www.w3.org/2001/XMLSchema#string

P2860

Circulating fibroblast growth factor 21 levels are closely associated with hepatic fat content: a cross-sectional study

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

FGF-21 as a novel metabolic regulator.

Obesity is a fibroblast growth factor 21 (FGF21)-resistant state

Endocrine fibroblast growth factors 15/19 and 21: from feast to famine

Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling

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29751-29765

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10.1074/JBC.M114.565960

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endoplasmic reticulum

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4207989

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