A simple p53 functional assay for screening cell lines, blood, and tumors.
about
Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimenA tobacco etch virus protease with increased substrate tolerance at the P1' positionLi-fraumeni syndromeClinical trials update of the European Organization for Research and Treatment of Cancer Breast Cancer GroupThe expanding role of yeast in cancer research and diagnosis: insights into the function of the oncosuppressors p53 and BRCA1/2Interaction of the Doa4 deubiquitinating enzyme with the yeast 26S proteasome.Activation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70p53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening systemAnalysis of missense variation in human BRCA1 in the context of interspecific sequence variationFunctional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversityChanges in allelic imbalances in locally advanced breast cancers after chemotherapy.Parallel analysis of tetramerization domain mutants of the human p53 protein using PCR colonies.Restoration of endogenous wild-type p53 activity in a glioblastoma cell line with intrinsic temperature-sensitive p53 induces growth arrest but not apoptosis.Use of a yeast assay to detect functional alterations in p53 in prostate cancer: review and future directions.Prognostic interaction between expression of p53 and estrogen receptor in patients with node-negative breast cancer: results from IBCSG Trials VIII and IXMolecular apocrine breast cancers are aggressive estrogen receptor negative tumors overexpressing either HER2 or GCDFP15.Germline p53 mutations in a cohort with childhood sarcoma: sex differences in cancer riskTumor suppressor activity of AP2alpha mediated through a direct interaction with p53.Benzo[a]pyrene, aflatoxine B₁ and acetaldehyde mutational patterns in TP53 gene using a functional assay: relevance to human cancer aetiologyp53 functional assays: detecting p53 mutations in both the germline and in sporadic tumours.TP53 status for prediction of sensitivity to taxane versus non-taxane neoadjuvant chemotherapy in breast cancer (EORTC 10994/BIG 1-00): a randomised phase 3 trial.Saccharomyces cerevisiae as a model system to study the response to anticancer agents.N-terminal domain of nuclear IL-1α shows structural similarity to the C-terminal domain of Snf1 and binds to the HAT/core module of the SAGA complex.Androgen receptor signaling and mutations in prostate cancerLi-Fraumeni syndrome--a molecular and clinical review.Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence.A meta-analysis of the relationship between FGFR3 and TP53 mutations in bladder cancer.Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.Tissue microarray cytometry reveals positive impact of homeodomain interacting protein kinase 2 in colon cancer survival irrespective of p53 functionTP53 status and response to treatment in breast cancersExpression of C-terminal deleted p53 isoforms in neuroblastoma.3-Methyl-3-deazaadenine, a stable isostere of N3-methyl-adenine, is efficiently bypassed by replication in vivo and by transcription in vitro.Gamma-tocotrienol and hydroxy-chavicol synergistically inhibits growth and induces apoptosis of human glioma cells.Evolution of p53 transactivation specificity through the lens of a yeast-based functional assayCyclophosphamide dose intensification may circumvent anthracycline resistance of p53 mutant breast cancers.Screen p53 mutations in hepatocellular carcinoma by FASAY: a novel splicing mutation.Whole-genome cartography of p53 response elements ranked on transactivation potential.Molecular and clinical differences between adenocarcinomas of the esophagus and of the gastric cardiaDevelopment of a yeast stop codon assay readily and generally applicable to human genes.Tumors associated with p53 germline mutations: a synopsis of 91 families.
P2860
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P2860
A simple p53 functional assay for screening cell lines, blood, and tumors.
description
1995 nî lūn-bûn
@nan
1995 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A simple p53 functional assay for screening cell lines, blood, and tumors.
@ast
A simple p53 functional assay for screening cell lines, blood, and tumors.
@en
A simple p53 functional assay for screening cell lines, blood, and tumors.
@nl
type
label
A simple p53 functional assay for screening cell lines, blood, and tumors.
@ast
A simple p53 functional assay for screening cell lines, blood, and tumors.
@en
A simple p53 functional assay for screening cell lines, blood, and tumors.
@nl
prefLabel
A simple p53 functional assay for screening cell lines, blood, and tumors.
@ast
A simple p53 functional assay for screening cell lines, blood, and tumors.
@en
A simple p53 functional assay for screening cell lines, blood, and tumors.
@nl
P2093
P2860
P4510
P356
P1476
A simple p53 functional assay for screening cell lines, blood, and tumors.
@en
P2093
Benhattar J
Chappuis P
Charbonnier F
Frebourg T
Limacher IM
Sappino AP
P2860
P304
P356
10.1073/PNAS.92.9.3963
P407
P577
1995-04-01T00:00:00Z