Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent.
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In Search of Enzymes with a Role in 3', 5'-Cyclic Guanosine Monophosphate Metabolism in PlantsSpeed, sensitivity, and stability of the light response in rod and cone photoreceptors: facts and modelsCaspase inhibition with XIAP as an adjunct to AAV vector gene-replacement therapy: improving efficacy and prolonging the treatment windowPhosphodiesterase 6C, cGMP-specific cone alpha'.Evolution and expression of the phosphodiesterase 6 genes unveils vertebrate novelty to control photosensitivity.Submembrane assembly and renewal of rod photoreceptor cGMP-gated channel: insight into the actin-dependent process of outer segment morphogenesis.The GAFa domain of phosphodiesterase-6 contains a rod outer segment localization signal.RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segmentsDistinct patterns of compartmentalization and proteolytic stability of PDE6C mutants linked to achromatopsia.Rod phosphodiesterase-6 (PDE6) catalytic subunits restore cone function in a mouse model lacking cone PDE6 catalytic subunit.Activation and quenching of the phototransduction cascade in retinal cones as inferred from electrophysiology and mathematical modelingTargeted ablation of the Pde6h gene in mice reveals cross-species differences in cone and rod phototransduction protein isoform inventory.Detergents stabilize the conformation of phosphodiesterase 6.Exchange of Cone for Rod Phosphodiesterase 6 Catalytic Subunits in Rod Photoreceptors Mimics in Part Features of Light Adaptation.Atypical retinal degeneration 3 in mice is caused by defective PDE6B pre-mRNA splicing.Comparative analysis of cone and rod transducins using chimeric Gα subunits.Functional mapping of interacting regions of the photoreceptor phosphodiesterase (PDE6) γ-subunit with PDE6 catalytic dimer, transducin, and regulator of G-protein signaling9-1 (RGS9-1).Cone phosphodiesterase-6α' restores rod function and confers distinct physiological properties in the rod phosphodiesterase-6β-deficient rd10 mouseOrigins of the phototransduction delay as inferred from stochastic and deterministic simulation of the amplification cascade.Cell type-specific translational profiling in the Xenopus laevis retina.Elevated cAMP improves signal-to-noise ratio in amphibian rod photoreceptors.Mechanisms of mutant PDE6 proteins underlying retinal diseases.Retinitis pigmentosa: impact of different Pde6a point mutations on the disease phenotype.It takes two transducins to activate the cGMP-phosphodiesterase 6 in retinal rodsImplications of dimeric activation of PDE6 for rod phototransduction
P2860
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P2860
Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent.
@ast
Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent.
@en
Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent.
@nl
type
label
Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent.
@ast
Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent.
@en
Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent.
@nl
prefLabel
Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent.
@ast
Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent.
@en
Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent.
@nl
P2860
P356
P1476
Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent
@en
P2093
Hakim Muradov
Kimberly K Boyd
P2860
P304
39828-39834
P356
10.1074/JBC.M110.170068
P407
P577
2010-10-12T00:00:00Z