From the cradle to the grave: molecular chaperones that may choose between folding and degradation.
about
p53-induced growth arrest is regulated by the mitochondrial SirT3 deacetylaseThe role of HDAC6 in cancerInteraction of Hsp90 with ribosomal proteins protects from ubiquitination and proteasome-dependent degradationDeletion of Phe508 in the first nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator increases its affinity for the heat shock cognate 70 chaperoneCHIP participates in protein triage decisions by preferentially ubiquitinating Hsp70-bound substratesInteraction of the Hsp90 cochaperone cyclophilin 40 with Hsc70BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP.The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulatorHECT and RING finger families of E3 ubiquitin ligases at a glanceHsp70 chaperones: cellular functions and molecular mechanismHSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradationChaperones in hepatitis C virus infectionDirect and Propagated Effects of Small Molecules on Protein-Protein Interaction NetworksFine-tuning multiprotein complexes using small moleculesTargeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseasesFeatures of protein-protein interactions that translate into potent inhibitors: topology, surface area and affinitySue1p is required for degradation of labile forms of altered cytochromes C in yeast mitochondria.Distinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast.Maintenance of structure and function of mitochondrial Hsp70 chaperones requires the chaperone Hep1.A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo.A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregatesThe cytosolic chaperone Hsc70 promotes traffic to the cell surface of intracellular retained melanocortin-4 receptor mutantsDefining the role for XAP2 in stabilization of the dioxin receptorC-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balancesRegulation of the cytoplasmic quality control protein degradation pathway by BAG2Organizing principles of mammalian nonsense-mediated mRNA decayA J domain virulence effector of Pseudomonas syringae remodels host chloroplasts and suppresses defensesA brain-specific isoform of small glutamine-rich tetratricopeptide repeat-containing protein binds to Hsc70 and the cysteine string proteinARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradationChaperone functions of the E3 ubiquitin ligase CHIP.Heat shock protein responses to aging and proteotoxicity in the olfactory bulb.In vitro characterization of six STUB1 variants in spinocerebellar ataxia 16 reveals altered structural properties for the encoded CHIP proteins.Protein stability and in vivo concentration of missense mutations in phenylalanine hydroxylase.Clathrin-independent endocytosis of ErbB2 in geldanamycin-treated human breast cancer cells.The mechanism whereby heat shock induces apoptosis depends on the innate sensitivity of cells to stress.Early transcriptional events linked to induction of diapause revealed by RNAseq in larvae of drosophilid fly, Chymomyza costata.The role of the UPS in cystic fibrosis.The BiP molecular chaperone plays multiple roles during the biogenesis of torsinA, an AAA+ ATPase associated with the neurological disease early-onset torsion dystonia.A targeted analysis of cellular chaperones reveals contrasting roles for heat shock protein 70 in flock house virus RNA replication.
P2860
Q21136386-6706176A-01EE-4AC1-9708-E4C18C98F2EEQ21296746-FC9B5B06-1E6D-47D1-899C-6EF674D09579Q24297095-E7C1ACD5-9CA6-422A-B4C5-CEDE67EA11C7Q24312937-7C9DFE00-1D2D-41D8-98D2-F29A34E89DBEQ24338386-5BE3947E-4EE2-4AD9-BDAD-8515B2E7F3A5Q24520314-764AED40-F576-49DD-9BC7-9155D9992E6BQ24534836-B98C718C-D0A0-495E-94C1-538D32F7345EQ24562651-44EB4866-AFCE-433E-86A1-05411AAB2ED4Q24599672-ED0A66A8-5326-4413-9305-EDC8077D7C1EQ24644472-DED961CB-1E89-4E0D-8D66-F6C8486598A9Q24679412-5E65DDA9-5AE2-49C9-BD0E-8D585997F18EQ26771251-D1F8EC15-349B-4C51-9C62-0FDEC1F1CA31Q26784027-01146F45-88A1-4B81-9F15-BF1891E89E80Q26822675-0120A97D-C93F-4671-B5AE-34D2BF2A89ACQ26859909-B1403E6C-A58A-43BC-A621-67B2B52038ADQ26996645-745B5DB4-E1AD-4C73-9A2A-9D9E79D6C126Q27934135-BE68064C-A4D6-4293-B4BB-D5160F2B45F7Q27934755-B44655A6-0AE1-4C1A-9EB8-DAA3894BD575Q27937151-36A9CCDE-8979-46A7-83B2-41B8FDA6A987Q27937987-E9D7F532-5589-40ED-9239-D2F189D85B72Q28078724-A84CA62F-2D93-4A65-B7D2-EA74D1A4E163Q28114913-38F310A5-2082-4E99-98AD-339FC3F97958Q28116061-B40AED92-2ACC-4A29-9CA7-C4E6844D2A59Q28184153-45DF6168-47C7-4695-96F7-4D9E27D54702Q28271643-0D8026E6-224F-44FD-9C61-0719DCA75A48Q28272894-41D26575-6331-4CBE-9E19-FE84EB99F45AQ28302705-DFE9182B-77D9-4D3B-A28D-CD8A7E4FBC4FQ28492431-A20D9FCA-F942-482D-92BC-2635DBBC924DQ28504634-347C606B-2F22-4E61-B388-28C6EC477E5CQ28771725-663754A2-134C-480D-AF5F-DA11B813C7CAQ30362083-215AC749-C50B-424D-9B4F-392FF63EC967Q30382422-A44ACC69-48F4-4A2E-99F8-DFC831E54336Q30400979-2A3A8FD3-529B-4B1C-9BEF-4ED2EE9EDE8FQ30407525-739C4316-BB56-4FDD-A606-9D0B414B2A4FQ30439237-726142BB-8DDA-4A23-88C7-8A2762DB4C81Q30494400-45D9064A-ACBE-4FBF-98A7-E9BB00F3BA65Q30665168-7308BA84-2603-400E-968B-ACEF59D735A4Q33307871-29A4045E-EC79-4E63-BD83-791E839A62C0Q33556224-AA9F39A3-C608-4163-AD0F-A9DC801BE64CQ33558724-CF4EE0EE-3384-40E6-A49E-0A1E5DF40BCB
P2860
From the cradle to the grave: molecular chaperones that may choose between folding and degradation.
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
From the cradle to the grave: ...... tween folding and degradation.
@ast
From the cradle to the grave: ...... tween folding and degradation.
@en
From the cradle to the grave: ...... tween folding and degradation.
@nl
type
label
From the cradle to the grave: ...... tween folding and degradation.
@ast
From the cradle to the grave: ...... tween folding and degradation.
@en
From the cradle to the grave: ...... tween folding and degradation.
@nl
prefLabel
From the cradle to the grave: ...... tween folding and degradation.
@ast
From the cradle to the grave: ...... tween folding and degradation.
@en
From the cradle to the grave: ...... tween folding and degradation.
@nl
P2093
P2860
P356
P1433
P1476
From the cradle to the grave: ...... tween folding and degradation.
@en
P2093
P2860
P304
P356
10.1093/EMBO-REPORTS/KVE206
P577
2001-10-01T00:00:00Z