Nature of pharmacophore influences active site specificity of proteasome inhibitors.
about
One-shot NMR analysis of microbial secretions identifies highly potent proteasome inhibitorIncorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like SitesSelective inhibition of the immunoproteasome by ligand-induced crosslinking of the active siteAssessing subunit dependency of the Plasmodium proteasome using small molecule inhibitors and active site probesDiscovery of a potent and highly β1 specific proteasome inhibitor from a focused library of urea-containing peptide vinyl sulfones and peptide epoxyketones.Molecular basis of differential sensitivity of myeloma cells to clinically relevant bolus treatment with bortezomib.Recent advances in proteasome inhibitor discovery.Subunit specific inhibitors of proteasomes and their potential for immunomodulationActivity-based imaging probes of the proteasome.Inhibitors of the immunoproteasome: current status and future directionsExploiting nature's rich source of proteasome inhibitors as starting points in drug development.Proteasome inhibitors: an expanding army attacking a unique target.Inhibitors for the immuno- and constitutive proteasome: current and future trends in drug development.Peptide-based proteasome inhibitors in anticancer drug design.Pharmacophore modeling technique applied for the discovery of proteasome inhibitors.Activity-based probes for the multicatalytic proteasome.Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib.Psoralenquinones as a novel class of proteasome inhibitors: design, synthesis and biological evaluation.Synthesis of C3/C1-Substituted Tetrahydroisoquinolines.A Set of Activity-Based Probes to Visualize Human (Immuno)proteasome Activities.
P2860
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P2860
Nature of pharmacophore influences active site specificity of proteasome inhibitors.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Nature of pharmacophore influences active site specificity of proteasome inhibitors.
@ast
Nature of pharmacophore influences active site specificity of proteasome inhibitors.
@en
Nature of pharmacophore influences active site specificity of proteasome inhibitors.
@nl
type
label
Nature of pharmacophore influences active site specificity of proteasome inhibitors.
@ast
Nature of pharmacophore influences active site specificity of proteasome inhibitors.
@en
Nature of pharmacophore influences active site specificity of proteasome inhibitors.
@nl
prefLabel
Nature of pharmacophore influences active site specificity of proteasome inhibitors.
@ast
Nature of pharmacophore influences active site specificity of proteasome inhibitors.
@en
Nature of pharmacophore influences active site specificity of proteasome inhibitors.
@nl
P2093
P2860
P50
P356
P1476
Nature of pharmacophore influences active site specificity of proteasome inhibitors.
@en
P2093
Alexandre A Pletnev
Alexei F Kisselev
Annet E M Blom
Martijn D P Risseeuw
Mathias J Voges
Matthew Britton
Michael Screen
Sondra L Downey
Wouter A van der Linden
P2860
P304
40125-40134
P356
10.1074/JBC.M110.160606
P407
P577
2010-10-11T00:00:00Z