Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model. - Wikidata - awgldk - TriplyDB

Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model.

Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model.

http://www.wikidata.org/entity/Q34401933

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Senescence in Human Mesenchymal Stem Cells: Functional Changes and Implications in Stem Cell-Based Therapy Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial Usage of Human Mesenchymal Stem Cells in Cell-based Therapy: Advantages and Disadvantages Potency of Human Cardiosphere-Derived Cells from Patients with Ischemic Heart Disease Is Associated with Robust Vascular Supportive Ability.Concise Review: Mesenchymal Stromal Cell-Based Approaches for the Treatment of Acute Respiratory Distress and Sepsis Syndromes.Mesenchymal stem cells as a therapeutic tool to treat sepsis.Compaction, fusion, and functional activation of three-dimensional human mesenchymal stem cell aggregate.Label-free assessment of replicative senescence in mesenchymal stem cells by Raman microspectroscopy A robust potency assay highlights significant donor variation of human mesenchymal stem/progenitor cell immune modulatory capacity and extended radio-resistance.Density-Dependent Metabolic Heterogeneity in Human Mesenchymal Stem Cells.Low-frequency, low-magnitude vibrations (LFLM) enhances chondrogenic differentiation potential of human adipose derived mesenchymal stromal stem cells (hASCs)Identity, proliferation capacity, genomic stability and novel senescence markers of mesenchymal stem cells isolated from low volume of human bone marrow.Increased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells' homeostasis.Melatonin Treatment Improves Mesenchymal Stem Cells Therapy by Preserving Stemness during Long-term In Vitro Expansion.Detection of mesenchymal stem cells senescence by prelamin A accumulation at the nuclear level.Mesenchymal stem cells in alleviating sepsis-induced mice cardiac dysfunction via inhibition of mTORC1-p70S6K signal pathway.Effects of mesenchymal stem cells from human induced pluripotent stem cells on differentiation, maturation, and function of dendritic cells Metabolic regulation of mesenchymal stem cell in expansion and therapeutic application.Human bone marrow stromal cells lose immunosuppressive and anti-inflammatory properties upon oncogenic transformation.Brief Report: Proteasomal Indoleamine 2,3-Dioxygenase Degradation Reduces the Immunosuppressive Potential of Clinical Grade-Mesenchymal Stromal Cells Undergoing Replicative Senescence.Intrinsic Variability Present in Wharton's Jelly Mesenchymal Stem Cells and T Cell Responses May Impact Cell Therapy.The antisenescence effect of trans-cinnamaldehyde on adipose-derived stem cells.miR-335 correlates with senescence/aging in human mesenchymal stem cells and inhibits their therapeutic actions through inhibition of AP-1 activity.Mesenchymal Stem Cells in Sepsis and Associated Organ Dysfunction: A Promising Future or Blind Alley?Oxidative Stress and Cellular Response to Doxorubicin: A Common Factor in the Complex Milieu of Anthracycline Cardiotoxicity.Material-induced Senescence (MIS): Fluidity Induces Senescent Type Cell Death of Lung Cancer Cells via Insulin-Like Growth Factor Binding Protein 5.Cell therapy for the treatment of sepsis and acute respiratory distress syndrome.Identifying hub genes and potential mechanisms associated with senescence in human annulus cells by gene expression profiling and bioinformatics analysis.Ubiquitin C decrement plays a pivotal role in replicative senescence of bone marrow mesenchymal stromal cells.Automated image analysis detects aging in clinical-grade mesenchymal stromal cell cultures.Reduced neuroprotective potential of the mesenchymal stromal cell secretome with ex vivo expansion, age and progressive multiple sclerosis.Comparison of proliferative and immunomodulatory potential of adipose-derived mesenchymal stem cells from young and geriatric cats.Large-Scale Expansion and Differentiation of Mesenchymal Stem Cells in Microcarrier-Based Stirred Bioreactors.Early passaging of mesenchymal stem cells does not instigate significant modifications in their immunological behavior.Aging- and Senescence-associated Changes of Mesenchymal Stromal Cells in Myelodysplastic Syndromes.Potency Analysis of Mesenchymal Stromal Cells Using a Combinatorial Assay Matrix Approach.

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P2860

Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model.

http://www.wikidata.org/entity/Q34401933

description

2014 nî lūn-bûn

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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2014 թվականի հուլիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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Cell senescence abrogates the ...... the lethal endotoxemia model.

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Cell senescence abrogates the ...... the lethal endotoxemia model.

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Cell senescence abrogates the ...... the lethal endotoxemia model.

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Cell senescence abrogates the ...... the lethal endotoxemia model.

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Cell senescence abrogates the ...... the lethal endotoxemia model.

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Cell senescence abrogates the ...... the lethal endotoxemia model.

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Cell senescence abrogates the ...... n the lethal endotoxemia model

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Antonio Bernad

http://www.w3.org/2001/XMLSchema#string

Juan Carlos Sepúlveda

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Judith Campisi

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Manuel A González

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María Tomé

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P2860

Identification of the cytolinker plectin as a major early in vivo substrate for caspase 8 during CD95- and tumor necrosis factor receptor-mediated apoptosis

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging

Interleukin-8, a chemotactic and inflammatory cytokine

A microRNA component of the p53 tumour suppressor network

Functional genetic screen for genes involved in senescence: role of Tid1, a homologue of the Drosophila tumor suppressor l(2)tid, in senescence and cell survival

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production

The immunomodulatory capacity of mesenchymal stem cells.

Replicative senescence of mesenchymal stem cells: a continuous and organized process

Histone deacetylase controls adult stem cell aging by balancing the expression of polycomb genes and jumonji domain containing 3

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1865-1877

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10.1002/STEM.1654

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7

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32

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Ma Eugenia Fernández

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260094518

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24496748

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4209016

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