Intraneuronal Abeta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease.
about
Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal modelsSystematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicityExtracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease.Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathologyA blood-brain barrier (BBB) disrupter is also a potent α-synuclein (α-syn) aggregation inhibitor: a novel dual mechanism of mannitol for the treatment of Parkinson disease (PD)Fenton chemistry and oxidative stress mediate the toxicity of the beta-amyloid peptide in a Drosophila model of Alzheimer's diseaseOverview of Alzheimer's Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compoundsβ-Amyloid: the key peptide in the pathogenesis of Alzheimer's diseaseGr33a modulates Drosophila male courtship preferenceNeurodegeneration in a Drosophila model for the function of TMCC2, an amyloid protein precursor-interacting and apolipoprotein E-binding proteinFlyglow: Single-fly observations of simultaneous molecular and behavioural circadian oscillations in controls and an Alzheimer's model.Role of Drosophila Amyloid Precursor Protein in Memory FormationModeling the complex pathology of Alzheimer's disease in DrosophilaDisruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid betaNeuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer diseaseSequestration of the Abeta peptide prevents toxicity and promotes degradation in vivoThe Toll-->NFkappaB signaling pathway mediates the neuropathological effects of the human Alzheimer's Abeta42 polypeptide in DrosophilaComplete phenotypic recovery of an Alzheimer's disease model by a quinone-tryptophan hybrid aggregation inhibitorCharacterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defectsCurcumin promotes A-beta fibrillation and reduces neurotoxicity in transgenic DrosophilaSystematic Aβ Analysis in Drosophila Reveals High Toxicity for the 1-42, 3-42 and 11-42 Peptides, and Emphasizes N- and C-Terminal ResiduesAgeing increases vulnerability to aβ42 toxicity in DrosophilaMetabolic changes may precede proteostatic dysfunction in a Drosophila model of amyloid beta peptide toxicityLithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer's diseaseOral Triphenylmethane Food Dye Analog, Brilliant Blue G, Prevents Neuronal Loss in APPSwDI/NOS2-/- Mouse Model.Oligomer-targeting with a conformational antibody fragment promotes toxicity in Aβ-expressing flies.Recent progress in understanding Alzheimer's β-amyloid structures.The pro-domains of neurotrophins, including BDNF, are linked to Alzheimer's disease through a toxic synergy with AβAlpha-helix targeting reduces amyloid-beta peptide toxicity.Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity.Secretory Carrier Membrane Protein (SCAMP) deficiency influences behavior of adult fliesMechanism of neuronal versus endothelial cell uptake of Alzheimer's disease amyloid beta proteinApolipoprotein E-mimetics inhibit neurodegeneration and restore cognitive functions in a transgenic Drosophila model of Alzheimer's diseaseMitochondrial mislocalization underlies Abeta42-induced neuronal dysfunction in a Drosophila model of Alzheimer's disease.Role of small oligomers on the amyloidogenic aggregation free-energy landscapeThe chaperone domain BRICHOS prevents CNS toxicity of amyloid-β peptide in Drosophila melanogasterInhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease.Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.Transgenic Drosophila models of Alzheimer's disease and tauopathiesLinking amyloid protein aggregation and yeast survival.
P2860
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P2860
Intraneuronal Abeta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Intraneuronal Abeta, non-amylo ...... model of Alzheimer's disease.
@ast
Intraneuronal Abeta, non-amylo ...... model of Alzheimer's disease.
@en
Intraneuronal Abeta, non-amylo ...... model of Alzheimer's disease.
@nl
type
label
Intraneuronal Abeta, non-amylo ...... model of Alzheimer's disease.
@ast
Intraneuronal Abeta, non-amylo ...... model of Alzheimer's disease.
@en
Intraneuronal Abeta, non-amylo ...... model of Alzheimer's disease.
@nl
prefLabel
Intraneuronal Abeta, non-amylo ...... model of Alzheimer's disease.
@ast
Intraneuronal Abeta, non-amylo ...... model of Alzheimer's disease.
@en
Intraneuronal Abeta, non-amylo ...... model of Alzheimer's disease.
@nl
P2093
P1433
P1476
Intraneuronal Abeta, non-amylo ...... a model of Alzheimer's disease
@en
P2093
Crowther DC
Kinghorn KJ
P304
P356
10.1016/J.NEUROSCIENCE.2004.12.025
P407
P577
2005-01-01T00:00:00Z