Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission
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Stem Cell Modeling of Core Binding Factor Acute Myeloid LeukemiaWhen stem cells grow old: phenotypes and mechanisms of stem cell agingEpigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical ImplicationsMolecular landscape of acute myeloid leukemia in younger adults and its clinical relevanceEpigenetic regulation of hematopoietic stem cell agingMolecular-defined clonal evolution in patients with chronic myeloid leukemia independent of the BCR-ABL status.Genomic Classification and Prognosis in Acute Myeloid Leukemia.DNMT3A and TET2 in the Pre-Leukemic Phase of Hematopoietic DisordersConcise Review: Induced Pluripotent Stem Cells as New Model Systems in OncologyAdvancing the Minimal Residual Disease Concept in Acute Myeloid LeukemiaAging-Induced Stem Cell Mutations as Drivers for Disease and CancerClonal hematopoiesis and blood-cancer risk inferred from blood DNA sequenceAge-related clonal hematopoiesis associated with adverse outcomesMeasurable residual disease testing in acute myeloid leukaemia.Molecular Basis and Targeted Inhibition of CBFβ-SMMHC Acute Myeloid Leukemia.Stem cells are units of natural selection for tissue formation, for germline development, and in cancer developmentPre-leukemic evolution of hematopoietic stem cells: the importance of early mutations in leukemogenesisHematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemiaEpigenetics in normal and malignant hematopoiesis: An overview and update 2017.Efficacy and Biological Correlates of Response in a Phase II Study of Venetoclax Monotherapy in Patients with Acute Myelogenous Leukemia.The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemiaQuiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycleIndividualizing Therapeutic Strategies in Acute Myeloid Leukemia: Moving Beyond the 'One-Size-Fits-All' Approach.NrasG12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis.A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells.DNMT3A in haematological malignancies.Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly.Preclinical efficacy of MEK inhibition in Nras-mutant AML.Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition.Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation.miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3aIsocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia.Controlling pre-leukemic thymocyte self-renewal.The crossroads between cancer stem cells and aging.Quantitative detection of DNMT3A R882H mutation in acute myeloid leukemiaTargeted Therapy of FLT3 in Treatment of AML-Current Status and Future Directions.Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell ActivityThe serum tryptase test: an emerging robust biomarker in clinical hematology.High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells.Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia.
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Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Preleukemic mutations in human ...... ators and persist in remission
@ast
Preleukemic mutations in human ...... ators and persist in remission
@en
Preleukemic mutations in human ...... ators and persist in remission
@nl
type
label
Preleukemic mutations in human ...... ators and persist in remission
@ast
Preleukemic mutations in human ...... ators and persist in remission
@en
Preleukemic mutations in human ...... ators and persist in remission
@nl
prefLabel
Preleukemic mutations in human ...... ators and persist in remission
@ast
Preleukemic mutations in human ...... ators and persist in remission
@en
Preleukemic mutations in human ...... ators and persist in remission
@nl
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P2860
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Preleukemic mutations in human ...... ators and persist in remission
@en
P2093
Bruno C Medeiros
Irving L Weissman
M Ryan Corces-Zimmerman
Ravindra Majeti
Wan-Jen Hong
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P304
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10.1073/PNAS.1324297111
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P577
2014-02-03T00:00:00Z