Specific interference of urokinase-type plasminogen activator receptor and matrix metalloproteinase-9 gene expression induced by double-stranded RNA results in decreased invasion, tumor growth, and angiogenesis in gliomas.
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Transcriptional activation of human matrix metalloproteinase-9 gene expression by multiple co-activatorsEpigenetic diet: impact on the epigenome and cancerHarnessing the RNA interference pathway to advance treatment and prevention of hepatocellular carcinomaTargeting tumor-associated macrophages to combat pancreatic cancerIdentification of uPAR-positive chemoresistant cells in small cell lung cancerAn extensive invasive intracranial human glioblastoma xenograft model: role of high level matrix metalloproteinase 9.MMP-9, uPAR and cathepsin B silencing downregulate integrins in human glioma xenograft cells in vitro and in vivo in nude mice.The role of MMP-9 in the anti-angiogenic effect of secreted protein acidic and rich in cysteine.Pleiotropic roles of matrix metalloproteinases in tumor angiogenesis: contrasting, overlapping and compensatory functions.Suppression of uPAR retards radiation-induced invasion and migration mediated by integrin β1/FAK signaling in medulloblastoma.Progress on antiangiogenic therapy for patients with malignant glioma.The pathobiology of glioma tumorsRegulation of DNA repair mechanism in human glioma xenograft cells both in vitro and in vivo in nude mice.Urokinase plasminogen activator receptor and/or matrix metalloproteinase-9 inhibition induces apoptosis signaling through lipid rafts in glioblastoma xenograft cellssiRNA-mediated downregulation of MMP-9 and uPAR in combination with radiation induces G2/M cell-cycle arrest in Medulloblastoma.Involvement of nitric oxide synthase in matrix metalloproteinase-9- and/or urokinase plasminogen activator receptor-mediated glioma cell migration.Urokinase and its receptors in chronic kidney disease.Gadd45a sensitizes medulloblastoma cells to irradiation and suppresses MMP-9-mediated EMTIntegrin α9β1-mediated cell migration in glioblastoma via SSAT and Kir4.2 potassium channel pathwayMMP-9 short interfering RNA induced senescence resulting in inhibition of medulloblastoma growth via p16(INK4a) and mitogen-activated protein kinase pathway.A suppressor of multiple extracellular matrix-degrading proteases and cancer metastasis.RNA interference-mediated targeting of urokinase plasminogen activator receptor and matrix metalloproteinase-9 gene expression in the IOMM-lee malignant meningioma cell line inhibits tumor growth, tumor cell invasion and angiogenesis.Caveolin-1, caveolae, and glioblastomaUrokinase-type plasminogen activator receptor (uPAR)-mediated regulation of WNT/β-catenin signaling is enhanced in irradiated medulloblastoma cells.Prospects of RNA interference therapy for cancer.RNAi based approaches to the treatment of malignant glioma.Matrix metalloproteinase-1 promotes prostate tumor growth and metastasis.MMP-9 and uPAR regulated glioma cell migrationMatrix metalloproteinases as potential targets in the venous dilation associated with varicose veins.Small interfering RNA directed reversal of urokinase plasminogen activator demethylation inhibits prostate tumor growth and metastasis.RNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth.Simultaneous downregulation of uPAR and MMP-9 induces overexpression of the FADD-associated protein RIP and activates caspase 9-mediated apoptosis in gliomas.Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma.Sphingosine-1-phosphate and interleukin-1 independently regulate plasminogen activator inhibitor-1 and urokinase-type plasminogen activator receptor expression in glioblastoma cells: implications for invasivenessInhibition of angiogenesis and invasion in malignant gliomas.Epigenetic regulation of miRNA-211 by MMP-9 governs glioma cell apoptosis, chemosensitivity and radiosensitivity.Interleukin-1 regulates the expression of sphingosine kinase 1 in glioblastoma cells.Inhibition of matrix metalloproteinase-2 enhances radiosensitivity by abrogating radiation-induced FoxM1-mediated G2/M arrest in A549 lung cancer cells.Concepts in in vivo siRNA delivery for cancer therapy.Human adipose-derived stem cell adipogenesis induces paracrine regulation of the invasive ability of MCF-7 human breast cancer cells in vitro.
P2860
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P2860
Specific interference of urokinase-type plasminogen activator receptor and matrix metalloproteinase-9 gene expression induced by double-stranded RNA results in decreased invasion, tumor growth, and angiogenesis in gliomas.
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Specific interference of uroki ...... , and angiogenesis in gliomas.
@ast
Specific interference of uroki ...... , and angiogenesis in gliomas.
@en
Specific interference of uroki ...... , and angiogenesis in gliomas.
@nl
type
label
Specific interference of uroki ...... , and angiogenesis in gliomas.
@ast
Specific interference of uroki ...... , and angiogenesis in gliomas.
@en
Specific interference of uroki ...... , and angiogenesis in gliomas.
@nl
prefLabel
Specific interference of uroki ...... , and angiogenesis in gliomas.
@ast
Specific interference of uroki ...... , and angiogenesis in gliomas.
@en
Specific interference of uroki ...... , and angiogenesis in gliomas.
@nl
P2093
P2860
P356
P1476
Specific interference of uroki ...... h, and angiogenesis in gliomas
@en
P2093
Dzung H Dinh
Jasti S Rao
Meena Gujrati
Sajani S Lakka
Velidi H Rao
William C Olivero
P2860
P304
21882-21892
P356
10.1074/JBC.M408520200
P407
P577
2005-04-11T00:00:00Z