CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery. - Wikidata - awgldk - TriplyDB

CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery.

CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery.

http://www.wikidata.org/entity/Q34412576

about

ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner P4-ATPases as Phospholipid Flippases-Structure, Function, and Enigmas Mammalian P4-ATPases and ABC transporters and their role in phospholipid transport Phospholipid flippase activities and substrate specificities of human type IV P-type ATPases localized to the plasma membrane P4-ATPases: lipid flippases in cell membranes Lipid somersaults: Uncovering the mechanisms of protein-mediated lipid flipping P4 ATPases: flippases in health and disease Atp8a1 deficiency is associated with phosphatidylserine externalization in hippocampus and delayed hippocampus-dependent learning Mapping functional interactions in a heterodimeric phospholipid pump Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4 A high-yield co-expression system for the purification of an intact Drs2p-Cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate.Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase.Phospholipid flippases: building asymmetric membranes and transport vesicles.Lipid Flippase Subunit Cdc50 Mediates Drug Resistance and Virulence in Cryptococcus neoformans Hepatobiliary transport in health and disease ATP11C mutation is responsible for the defect in phosphatidylserine uptake in UPS-1 cells.Biochemical characterization of P4-ATPase mutations identified in patients with progressive familial intrahepatic cholestasis Role of post-translational modifications at the β-subunit ectodomain in complex association with a promiscuous plant P4-ATPase ATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes.Flipping and flopping--lipids on the move.Phospholipid Flippase ATP10A Translocates Phosphatidylcholine and Is Involved in Plasma Membrane Dynamics.Loss of Tmem30a leads to photoreceptor degeneration.High phosphatidylinositol 4-phosphate (PI4P)-dependent ATPase activity for the Drs2p-Cdc50p flippase after removal of its N- and C-terminal extensions.Cellular localization and biochemical analysis of mammalian CDC50A, a glycosylated β-subunit for P4 ATPases.The phospholipid flippase ATP9A is required for the recycling pathway from the endosomes to the plasma membrane Critical role of the beta-subunit CDC50A in the stable expression, assembly, subcellular localization, and lipid transport activity of the P4-ATPase ATP8A2 Plasmalogen biosynthesis is spatiotemporally regulated by sensing plasmalogens in the inner leaflet of plasma membranes.Phosphatidylserine stimulation of Drs2p·Cdc50p lipid translocase dephosphorylation is controlled by phosphatidylinositol-4-phosphate.Outside of the box: recent news about phospholipid translocation by P4 ATPases.The CDC50A extracellular domain is required for forming a functional complex with and chaperoning phospholipid flippases to the plasma membrane.Aspergillus nidulans flippase DnfA is cargo of the endocytic collar and plays complementary roles in growth and phosphatidylserine asymmetry with another flippase, DnfB.Substrate trajectory through phospholipid-transporting P4-ATPases.Functional role of evolutionarily highly conserved residues, N-glycosylation level and domains of the Leishmania miltefosine transporter-Cdc50 subunit Disruption of Tmem30a results in cerebellar ataxia and degeneration of Purkinje cells TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes

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CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery.

http://www.wikidata.org/entity/Q34412576

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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CDC50 proteins are critical co ...... P4-ATPase transport machinery.

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CDC50 proteins are critical co ...... P4-ATPase transport machinery.

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CDC50 proteins are critical co ...... P4-ATPase transport machinery.

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JBC.M110.139543

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Journal of Biological Chemistry

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CDC50 proteins are critical co ...... P4-ATPase transport machinery.

@en

P2093

Guillaume Lenoir

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Hanka Hennrich

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Joost C M Holthuis

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Patricia M Verhulst

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Philippe F Devaux

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Susanne Bryde

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P2860

Crystal structure of the sodium–potassium pump

FIC1, the protein affected in two forms of hereditary cholestasis, is localized in the cholangiocyte and the canalicular membrane of the hepatocyte

Chilling tolerance in Arabidopsis involves ALA1, a member of a new family of putative aminophospholipid translocases

Membrane lipids: where they are and how they behave

The structural basis of calcium transport by the calcium pump

Crystal structure of the sodium-potassium pump at 2.4 A resolution

A novel membrane protein, Ros3p, is required for phospholipid translocation across the plasma membrane in Saccharomyces cerevisiae.

Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae.

Loss of P4 ATPases Drs2p and Dnf3p disrupts aminophospholipid transport and asymmetry in yeast post-Golgi secretory vesicles

Roles for the Drs2p-Cdc50p complex in protein transport and phosphatidylserine asymmetry of the yeast plasma membrane.

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40562-40572

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scholarly article

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10.1074/JBC.M110.139543

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52

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285

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2010-10-20T00:00:00Z

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20961850

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3003355

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