The p16(INK4A) tumor suppressor regulates cellular oxidative stress
about
Melanocytes as instigators and victims of oxidative stressCapturing the biological impact of CDKN2A and MC1R genes as an early predisposing event in melanoma and non melanoma skin cancerTelomere length and the risk of cutaneous malignant melanoma in melanoma-prone families with and without CDKN2A mutations.Role of p16INK4a and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells.Melanoma genotypes and phenotypes get personal.Constitutive mitochondrial DNA copy number in peripheral blood of melanoma families with and without CDKN2A mutationsModelling the onset of senescence at the G1/S cell cycle checkpoint.The Aplidin analogs PM01215 and PM02781 inhibit angiogenesis in vitro and in vivo.Oxidative stress in aging human skin.Combined activation of the energy and cellular-defense pathways may explain the potent anti-senescence activity of methylene blue.Absence of AMPKα2 accelerates cellular senescence via p16 induction in mouse embryonic fibroblasts.Genetics of melanomaFamilial melanoma-associated mutations in p16 uncouple its tumor-suppressor functionsGDF15 contributes to radiation-induced senescence through the ROS-mediated p16 pathway in human endothelial cells.Selenium for the prevention of cutaneous melanoma.CtBP1 is expressed in melanoma and represses the transcription of p16INK4a and Brca1.Survivin promotion of melanoma metastasis requires upregulation of α5 integrinKnockdown of CMTM3 promotes metastasis of gastric cancer via the STAT3/Twist1/EMT signaling pathway.The interplay between p16 serine phosphorylation and arginine methylation determines its function in modulating cellular apoptosis and senescence.Cellular Mechanisms of Oxidative Stress and Action in Melanoma.Loss of INK4a/Arf gene enhances ultraviolet radiation-induced cutaneous tumor development.The role of reactive oxygen species and subsequent DNA-damage response in the emergence of resistance towards resveratrol in colon cancer models.Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer.Mechanisms and prevention of UV-induced melanoma.Association between chromosomal aberration of exfoliated bladder cells in the urine and oxidative stress in patients with bladder transitional cell carcinoma.Loss of p16INK4A stimulates aberrant mitochondrial biogenesis through a CDK4/Rb-independent pathway.Transient postnatal overfeeding causes liver stress-induced premature senescence in adult mice.Role of melanin in melanocyte dysregulation of reactive oxygen species.A Phase II Randomized Placebo-Controlled Trial of Oral N-acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress In Vivo.Reactive oxygen species-dependent down-regulation of tumor suppressor genes PTEN, USP28, DRAM, TIGAR, and CYLD under oxidative stress.A short acidic motif in ARF guards against mitochondrial dysfunction and melanoma susceptibility.Significance of the melanocortin 1 receptor in the DNA damage response of human melanocytes to ultraviolet radiation.miR-200a Modulates the Expression of the DNA Repair Protein OGG1 Playing a Role in Aging of Primary Human Keratinocytes.Cold atmospheric plasma treatment of melanoma and glioblastoma cancer cells
P2860
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P2860
The p16(INK4A) tumor suppressor regulates cellular oxidative stress
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The p16
@nl
The p16(INK4A) tumor suppressor regulates cellular oxidative stress
@ast
The p16(INK4A) tumor suppressor regulates cellular oxidative stress
@en
type
label
The p16
@nl
The p16(INK4A) tumor suppressor regulates cellular oxidative stress
@ast
The p16(INK4A) tumor suppressor regulates cellular oxidative stress
@en
prefLabel
The p16
@nl
The p16(INK4A) tumor suppressor regulates cellular oxidative stress
@ast
The p16(INK4A) tumor suppressor regulates cellular oxidative stress
@en
P2093
P2860
P356
P1433
P1476
The p16(INK4A) tumor suppressor regulates cellular oxidative stress
@en
P2093
A G Goodson
D Grossman
G Samadashwily
K M Boucher
N C Jenkins
S A Leachman
P2860
P2888
P304
P356
10.1038/ONC.2010.419
P407
P577
2010-09-13T00:00:00Z
P5875
P6179
1015311906