Dipyrimidine amines: a novel class of chemokine receptor type 4 antagonists with high specificity. - Wikidata - awgldk - TriplyDB

Dipyrimidine amines: a novel class of chemokine receptor type 4 antagonists with high specificity.

Dipyrimidine amines: a novel class of chemokine receptor type 4 antagonists with high specificity.

http://www.wikidata.org/entity/Q34414241

about

Development of a unique small molecule modulator of CXCR4 Inhibition of the CXCL12/CXCR4-axis as preventive therapy for radiation-induced pulmonary fibrosis Expression of CXCL10 is associated with response to radiotherapy and overall survival in squamous cell carcinoma of the tongue.Fragment-based optimization of small molecule CXCL12 inhibitors for antagonizing the CXCL12/CXCR4 interaction.Small molecule inhibitors of CXCR4.Inhibition of angiogenesis, fibrosis and thrombosis by tetramethylpyrazine: mechanisms contributing to the SDF-1/CXCR4 axis.Process of hepatic metastasis from pancreatic cancer: biology with clinical significance.Structure-based ligand discovery for the protein-protein interface of chemokine receptor CXCR4 Development of CXCR4 modulators by virtual HTS of a novel amide-sulfamide compound library.Distinct modifications in Kv2.1 channel via chemokine receptor CXCR4 regulate neuronal survival-death dynamics.The successes and failures of HIV drug discovery.Imaging agents for the chemokine receptor 4 (CXCR4).Synthesis and evaluation of an (18)F-labeled pyrimidine-pyridine amine for targeting CXCR4 receptors in gliomas.Downregulation of microRNA-206 promotes invasion and angiogenesis of triple negative breast cancer.Benzenesulfonamides: a unique class of chemokine receptor type 4 inhibitors.Symmetrical bis-tertiary amines as novel CXCR4 inhibitors Harnessing CXCR4 antagonists in stem cell mobilization, HIV infection, ischemic diseases, and oncology.Synthesis of pyridine derivatives as potential antagonists of chemokine receptor type 4.Computational analysis of the structural mechanism of inhibition of chemokine receptor CXCR4 by small molecule antagonists.High-level expression of CXCR4 in breast cancer is associated with early distant and bone metastases.Targeting CXCL12/CXCR4 Axis in Tumor Immunotherapy.Novel anti-inflammatory agents targeting CXCR4: Design, synthesis, biological evaluation and preliminary pharmacokinetic study.Anti-inflammatory hybrids of secondary amines and amide-sulfamide derivatives.

P2860

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P2860

Dipyrimidine amines: a novel class of chemokine receptor type 4 antagonists with high specificity.

http://www.wikidata.org/entity/Q34414241

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Dipyrimidine amines: a novel c ...... gonists with high specificity.

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Dipyrimidine amines: a novel c ...... gonists with high specificity.

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Dipyrimidine amines: a novel c ...... gonists with high specificity.

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Dipyrimidine amines: a novel c ...... gonists with high specificity.

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Dipyrimidine amines: a novel c ...... gonists with high specificity.

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Dipyrimidine amines: a novel c ...... gonists with high specificity.

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Dipyrimidine amines: a novel c ...... gonists with high specificity.

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P1433

Journal of Medicinal Chemistry

P1476

Dipyrimidine amines: a novel c ...... gonists with high specificity.

@en

P2093

Aizhi Zhu

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Dennis C Liotta

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Hans E Grossniklaus

http://www.w3.org/2001/XMLSchema#string

Hua Yang

http://www.w3.org/2001/XMLSchema#string

Hyunsuk Shim

http://www.w3.org/2001/XMLSchema#string

James P Snyder

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Jianguo Xu

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Mark Lockwood

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Mauricio Rojas

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Weiqiang Zhan

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P2860

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway

CXCR4 modulates contractility in adult cardiac myocytes

CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

Latent variables and structural equation models for longitudinal relationships: an illustration in nutritional epidemiology.

Lymphocyte trafficking and regional immunity.

Reductive Amination of Aldehydes and Ketones with Sodium Triacetoxyborohydride. Studies on Direct and Indirect Reductive Amination Procedures(1).

Peptide-lead CXCR4 antagonists with high anti-HIV activity.

G-protein-coupled receptors and cancer.

Pharmacological evidence for complex and multiple site interaction of CXCR4 with SDF-1alpha: implications for development of selective CXCR4 antagonists.

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8556-8568

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scholarly article

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10.1021/JM100786G

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24

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53

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2010-11-24T00:00:00Z

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21105715

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3003753

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