Functional genetic variants that increase synaptic serotonin and 5-HT3 receptor sensitivity predict alcohol and drug dependence. - Wikidata - awgldk - TriplyDB

Functional genetic variants that increase synaptic serotonin and 5-HT3 receptor sensitivity predict alcohol and drug dependence.

Functional genetic variants that increase synaptic serotonin and 5-HT3 receptor sensitivity predict alcohol and drug dependence.

http://www.wikidata.org/entity/Q34414342

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The genetic basis of addictive disorders Genetic influences on the development of alcoholism Serotonin Transporter and Tryptophan Hydroxylase Gene Variations Mediate Working Memory Deficits of Cocaine Users Association and interaction analyses of 5-HT3 receptor and serotonin transporter genes with alcohol, cocaine, and nicotine dependence using the SAGE data.Association, interaction, and replication analysis of genes encoding serotonin transporter and 5-HT3 receptor subunits A and B in alcohol dependence Determination of genotype combinations that can predict the outcome of the treatment of alcohol dependence using the 5-HT(3) antagonist ondansetron.Serotonin transporter and receptor genes significantly impact nicotine dependence through genetic interactions in both European American and African American smokers Prenatal and childhood growth, and hospitalization for alcohol use disorders in adulthood: the Helsinki birth cohort study.Genetic influences on response to alcohol and response to pharmacotherapies for alcoholism.Neurotransmitters in alcoholism: A review of neurobiological and genetic studies.Genetics of alcohol dependence.Association of the 5-HTT gene-linked promoter region (5-HTTLPR) polymorphism with psychiatric disorders: review of psychopathology and pharmacotherapy.Functional and structural neural network characterization of serotonin transporter knockout rats.An exploration of the serotonin system in antisocial boys with high levels of callous-unemotional traits.A mouse model to address unresolved antidepressant issues Histone acetylation of the htr3a gene in the prefrontal cortex of Wistar rats regulates ethanol-seeking behavior.The influence of gene-environment interactions on alcohol consumption and alcohol use disorders: a comprehensive review.Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction.Polymorphisms of the serotonin transporter and receptor genes: susceptibility to substance abuse Estimating ancestral proportions in a multi-ethnic US sample: implications for studies of admixed populations.A review of 5-HT transporter linked promoter region (5-HTTLPR) polymorphism and associations with alcohol use problems and sexual risk behaviors.Differences in regional cerebral blood flow response to a 5HT3 antagonist in early- and late-onset cocaine-dependent subjects.The serotonin 5-HT3 receptor: a novel neurodevelopmental target.Susceptibility loci for heroin and cocaine addiction in the serotonergic and adrenergic pathways in populations of different ancestry Polymorphism in serotonin receptor 3B is associated with pain catastrophizing.Zebrafish: a model for the study of addiction genetics Introduction to the special issue "Pharmacotherapies for the treatment of alcohol abuse and dependence" and a summary of patents targeting other neurotransmitter systems.Serotonin functioning and adolescents' alcohol use: A genetically informed study examining mechanisms of risk.Neuroimaging methods for adolescent substance use disorder prevention science.HTR3A and HTR3E gene polymorphisms and diarrhea predominant irritable bowel syndrome risk: evidence from a meta-analysis.Serotonin-transporter promoter polymorphism modulates the ability to control food intake: Effect on total weight loss.The association of HTR3A mRNA expression and craving in Han Chinese alcohol-dependent patients: a preliminary study.Median and Dorsal Raphe Serotonergic Neurons Control Moderate Versus Compulsive Cocaine Intake.The Human Serotonin Type 3 Receptor Gene (HTR3A-E) Allelic Variant Database.Association study of 37 genes related to serotonin and dopamine neurotransmission and neurotrophic factors in cocaine dependence.Promising pharmacogenetic targets for treating alcohol use disorder: evidence from preclinical models.Association and cis-mQTL analysis of variants in serotonergic genes associated with nicotine dependence in Chinese Han smokers

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P2860

Functional genetic variants that increase synaptic serotonin and 5-HT3 receptor sensitivity predict alcohol and drug dependence.

http://www.wikidata.org/entity/Q34414342

description

2010 nî lūn-bûn

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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Functional genetic variants th ...... t alcohol and drug dependence.

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Functional genetic variants th ...... t alcohol and drug dependence.

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Functional genetic variants th ...... t alcohol and drug dependence.

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Functional genetic variants th ...... t alcohol and drug dependence.

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Functional genetic variants th ...... t alcohol and drug dependence.

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Functional genetic variants th ...... t alcohol and drug dependence.

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Functional genetic variants th ...... t alcohol and drug dependence.

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Molecular Psychiatry

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P2860

The 5-HT3B subunit is a major determinant of serotonin-receptor function

HTR3B is associated with alcoholism with antisocial behavior and alpha EEG power--an intermediate phenotype for alcoholism and co-morbid behaviors

High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptor

The 5-HT3 receptor as a therapeutic target

The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit

Immunolabelling of the 5-HT 3B receptor subunit in the central and peripheral nervous systems in rodents

A comparison of bayesian methods for haplotype reconstruction from population genotype data.

5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression

Update on neuropharmacological treatments for alcoholism: scientific basis and clinical findings.

3B but which 3B and that's just one of the questions: the heterogeneity of human 5-HT3 receptors.

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20838391

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substance dependence

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