Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha. - Wikidata - awgldk - TriplyDB

Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha.

Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha.

http://www.wikidata.org/entity/Q34420371

about

Links between metabolism and cancer Energy metabolism in neuroblastoma and Wilms tumor HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma MYC on the path to cancer A novel ent-kaurane diterpenoid executes antitumor function in colorectal cancer cells by inhibiting Wnt/β-catenin signaling.Cellular memory of hypoxia elicits neuroblastoma metastasis and enables invasion by non-aggressive neighbouring cells.From Krebs to clinic: glutamine metabolism to cancer therapy.The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy.Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells.HIF-1α confers aggressive malignant traits on human tumor cells independent of its canonical transcriptional function Hypoxic stress induces, but cannot sustain trophoblast stem cell differentiation to labyrinthine placenta due to mitochondrial insufficiency.Serine catabolism regulates mitochondrial redox control during hypoxia Inhibition of AMPK and Krebs cycle gene expression drives metabolic remodeling of Pten-deficient preneoplastic thyroid cells.MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer.Silencing gastrin-releasing peptide receptor suppresses key regulators of aerobic glycolysis in neuroblastoma cells Sunitinib suppress neuroblastoma growth through degradation of MYCN and inhibition of angiogenesis TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.Therapeutic targeting of cancer cell metabolism.Paracrine signaling through MYCN enhances tumor-vascular interactions in neuroblastoma.Treatment of a chemoresistant neuroblastoma cell line with the antimalarial ozonide OZ513.Nifurtimox reduces N-Myc expression and aerobic glycolysis in neuroblastoma.Lactate dehydrogenase A negatively regulated by miRNAs promotes aerobic glycolysis and is increased in colorectal cancer.Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation.Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2 The miR-34a-LDHA axis regulates glucose metabolism and tumor growth in breast cancer HIF2A and IGF2 expression correlates in human neuroblastoma cells and normal immature sympathetic neuroblasts.Molecular imaging of neuroblastoma progression in TH-MYCN transgenic mice.MYC, metabolism, cell growth, and tumorigenesis.Diagnostic FDG and FDOPA positron emission tomography scans distinguish the genomic type and treatment outcome of neuroblastoma.MYC degradation under low O2 tension promotes survival by evading hypoxia-induced cell death.Down-Regulated Phosphoglycerate Kinase 1 Expression Is Associated With Poor Prognosis in Patients With Gallbladder Cancer.miR-200b is a key regulator of tumor progression and metabolism targeting lactate dehydrogenase A in human malignant glioma.Modulation of hypoxia-inducible factors (HIF) from an integrative pharmacological perspective.Therapeutic targets in cancer cell metabolism and autophagy.Molecular Pathways: Targeting MYC-induced metabolic reprogramming and oncogenic stress in cancer.The influence of pH and hypoxia on tumor metastasis.

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Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha.

http://www.wikidata.org/entity/Q34420371

description

2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Combinatorial regulation of ne ...... a inducible factor HIF-1alpha.

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Combinatorial regulation of ne ...... a inducible factor HIF-1alpha.

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Combinatorial regulation of ne ...... a inducible factor HIF-1alpha.

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Combinatorial regulation of ne ...... a inducible factor HIF-1alpha.

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Combinatorial regulation of ne ...... a inducible factor HIF-1alpha.

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Combinatorial regulation of ne ...... a inducible factor HIF-1alpha.

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prefLabel

Combinatorial regulation of ne ...... a inducible factor HIF-1alpha.

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Combinatorial regulation of ne ...... a inducible factor HIF-1alpha.

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Combinatorial regulation of ne ...... a inducible factor HIF-1alpha.

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0008-5472.CAN-10-0740

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Cancer Research

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Combinatorial regulation of ne ...... a inducible factor HIF-1alpha.

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P2093

Bruce Pawel

http://www.w3.org/2001/XMLSchema#string

Daniel Martinez

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Guoliang Qing

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John M Maris

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M Celeste Simon

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Nicolas Skuli

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Patrick A Mayes

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P2860

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis

Common variations in BARD1 influence susceptibility to high-risk neuroblastoma

Identification of ALK as a major familial neuroblastoma predisposition gene

Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

Why do cancers have high aerobic glycolysis?

Cancer cell metabolism: Warburg and beyond

Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus

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10351-10361

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scholarly article

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24

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20961996

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