Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine - Wikidata - awgldk - TriplyDB

Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine

Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine

http://www.wikidata.org/entity/Q34422105

about

Metabolomics and Type 2 Diabetes: Translating Basic Research into Clinical Application Diabetes and Alzheimer disease, two overlapping pathologies with the same background: oxidative stress Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling Finding needles in a haystack: application of network analysis and target enrichment studies for the identification of potential anti-diabetic phytochemicals Random Survival Forest in practice: a method for modelling complex metabolomics data in time to event analysis.Hydrogen sulfide upregulates glutamate-cysteine ligase catalytic subunit, glutamate-cysteine ligase modifier subunit, and glutathione and inhibits interleukin-1β secretion in monocytes exposed to high glucose levels.Vitamin D upregulates glutamate cysteine ligase and glutathione reductase, and GSH formation, and decreases ROS and MCP-1 and IL-8 secretion in high-glucose exposed U937 monocytes Effect of chromium dinicocysteinate supplementation on circulating levels of insulin, TNF-α, oxidative stress, and insulin resistance in type 2 diabetic subjects: randomized, double-blind, placebo-controlled study Gene-Diet Interactions in Type 2 Diabetes: The Chicken and Egg Debate Personalized metabolomics for predicting glucose tolerance changes in sedentary women after high-intensity interval training.Vitamin D and L-cysteine levels correlate positively with GSH and negatively with insulin resistance levels in the blood of type 2 diabetic patients Hydrogen sulfide prevents hydrogen peroxide-induced activation of epithelial sodium channel through a PTEN/PI(3,4,5)P3 dependent pathway Serum glycine is associated with regional body fat and insulin resistance in functionally-limited older adults Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation Elevated serum levels of cysteine and tyrosine: early biomarkers in asymptomatic adults at increased risk of developing metabolic syndrome.Deciphering deterioration mechanisms of complex diseases based on the construction of dynamic networks and systems analysis.Hydrogen sulfide and L-cysteine increase phosphatidylinositol 3,4,5-trisphosphate (PIP3) and glucose utilization by inhibiting phosphatase and tensin homolog (PTEN) protein and activating phosphoinositide 3-kinase (PI3K)/serine/threonine protein kin Plasma biomarkers of oxidative stress and genetic variants in age-related macular degeneration.Can L-Cysteine and Vitamin D Rescue Vitamin D and Vitamin D Binding Protein Levels in Blood Plasma of African American Type 2 Diabetic Patients?Nutritional regulation of insulin secretion: implications for diabetes.NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice Increase in Blood Glutathione and Erythrocyte Proteins Related to Glutathione Generation, Reduction and Utilization in African-American Old Women with Diabetes.Identification and Antioxidant Activity of the Extracts of Eugenia uniflora Leaves. Characterization of the Anti-Inflammatory Properties of Aqueous Extract on Diabetes Expression in an Experimental Model of Spontaneous Type 1 Diabetes (NOD Mice).Glutaredoxin mediated redox effects of coenzyme Q10 treatment in type 1 and type 2 diabetes patients Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach.1,25(OH)2D3 inhibits oxidative stress and monocyte adhesion by mediating the upregulation of GCLC and GSH in endothelial cells treated with acetoacetate (ketosis).Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes Glutathione maintenance mitigates age-related susceptibility to redox cycling agents.Hepatic transcriptome implications for palm fruit juice deterrence of type 2 diabetes mellitus in young male Nile rats.Effect of increasing glutathione with cysteine and glycine supplementation on mitochondrial fuel oxidation, insulin sensitivity, and body composition in older HIV-infected patients.Associations of FPG, A1C and disease duration with protein markers of oxidative damage and antioxidative defense in type 2 diabetes and diabetic retinopathy.Metabolic heterogeneity of follicular amino acids in polycystic ovary syndrome is affected by obesity and related to pregnancy outcome.A Western diet induced NAFLD in LDLR(-/)(-) mice is associated with reduced hepatic glutathione synthesis.Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload.Plasma-free amino acid profiles are predictors of cancer and diabetes development.High-precision mass spectrometric analysis using stable isotopes in studies of children.L-cysteine supplementation as an adjuvant therapy for type-2 diabetes.Glycine metabolism in animals and humans: implications for nutrition and health.A new perspective on the importance of glycine conjugation in the metabolism of aromatic acids.Immunological mechanisms contributing to the double burden of diabetes and intracellular bacterial infections.

P2860

Q26774386-B5D82592-4A82-4A6D-B73E-1ABE96944B8B Q27022552-93DABFC7-1AFB-44E1-BD60-BE91A38BD516 Q28389739-3EB024DE-6AC5-4A10-8D39-1E69D8851C75 Q28544976-C1594862-1FC3-4955-92A0-80B2DEF523E0 Q31126519-86C5CFA7-F4EE-4594-ABB4-D43190DD7F09 Q33730119-E7682DFA-8E73-4778-95A2-FBB4B5EB40EF Q33777718-C4154BFF-C141-424E-9D9D-F4FB3DA3875D Q33830391-99E41A12-4737-4665-BE1A-C0068E92FF5A Q33838645-9521658C-3D78-4B2A-AAC9-60F7523485CA Q34101173-7DFD15AC-FD1B-4AE1-AE5C-23B3E2DBC7E4 Q34315524-A8342AA8-127A-4F99-8D5F-88AA1D7F8251 Q34760443-9D017726-7EDD-4244-A1AB-49A0306BE5AA Q35082745-143A05D5-93D6-47B5-A680-F916FA1F70A2 Q35163911-FD9CA036-EDE4-42D4-8DC9-C7706D84583C Q35189600-74EE49BA-B285-4368-BA14-9914249C32FB Q35193662-39404852-F8F2-4D5C-A25F-53D5797DB663 Q35562685-DCAF887E-5B3A-4EAF-9D67-112907913363 Q35784919-DF0B5DA3-3F38-411F-BCF8-3803704F1A7D Q36030261-932DA25C-8C00-4D52-8561-AC2D0AC9023F Q36071152-838839E0-9536-4318-9B30-295FB0EB89CE Q36422396-249BD05F-D965-47B6-B38D-D5BAF26B81A1 Q36455206-F9EFF891-F1F2-4B2F-BE02-A6D6BFC9DBC3 Q36462872-AF9B8AC1-4C6D-4162-8E17-A0CD6758B538 Q36534861-ED362C8E-DF79-4F83-9C41-82E273D6E059 Q36560652-AE854F87-6108-4E28-98DD-FBAE4645CDBC Q36781035-ABD2FBB4-DD4E-478F-8ED2-E3E805173FE6 Q36867636-A34EAEA5-FD1A-428A-B655-F0B20CF885B4 Q37293046-C664B29E-DC28-45B5-9E46-21B0A19038E9 Q37358926-49F14CAD-B84C-455B-B37F-66B507168DD0 Q37428930-0E06DCD4-D731-4D4C-ADEC-805A2753160F Q37457103-EA536C9E-7B30-4BF5-B409-F20B631A819C Q37501409-D4088084-BAAF-44F3-A60B-52C411AB509D Q37631366-803ADA09-4E30-4E0A-9672-B5E76CCD7AD0 Q37662139-FB9DC882-3DE8-4261-BD39-A3B8EE8C7333 Q37737774-04EA8A3B-3A81-4DB5-93F8-DDCC5F07A5DF Q37902616-3B14C9DB-7ADA-46CF-8A9D-2B44CBEC3755 Q38025442-78581384-BB1B-4416-9A7A-39625A3B8A7A Q38101481-EDE41E1C-146F-484D-B6B6-E10032523E42 Q38206257-4A9982ED-E173-490A-97E1-1B2E5352074C Q38254986-A98A923C-AE74-456D-A4D0-35977B3A8C8F

P2860

Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine

http://www.wikidata.org/entity/Q34422105

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Glutathione synthesis is dimin ...... tion with cysteine and glycine

@ast

Glutathione synthesis is dimin ...... tion with cysteine and glycine

@en

Glutathione synthesis is dimin ...... tion with cysteine and glycine

@nl

type

label

Glutathione synthesis is dimin ...... tion with cysteine and glycine

@ast

Glutathione synthesis is dimin ...... tion with cysteine and glycine

@en

Glutathione synthesis is dimin ...... tion with cysteine and glycine

@nl

prefLabel

Glutathione synthesis is dimin ...... tion with cysteine and glycine

@ast

Glutathione synthesis is dimin ...... tion with cysteine and glycine

@en

Glutathione synthesis is dimin ...... tion with cysteine and glycine

@nl

P1433

Q34422105-FE98C455-4CA6-472F-B41A-68924B4EC061

P1476

Q34422105-B9E6A846-D008-4264-9C44-F746D47AA2AF

P2093

Q34422105-11EA110A-DB79-46D1-9287-317FE230AFE0

Q34422105-1242B1CF-4984-46D2-AA1D-6F259145F36D

Q34422105-39802B44-33C3-4D44-9D68-D10226C472E9

Q34422105-54718A09-39C5-43EF-BEB9-A073CC2F1443

Q34422105-914BA3EF-01B2-43A2-A5E7-564AD3CAAC1F

Q34422105-B902C92A-E658-4802-94DC-90ED7DBCDD1E

Q34422105-DCD835D7-D253-484C-8BD6-68F8BBFD4304

P2860

Q34422105-00DA2C8B-F1E0-4D40-9290-2E6F38C2A7CB

Q34422105-2A4C5BA9-774B-4144-BB49-8C6C165DA8FF

Q34422105-2D6D732C-776B-4D13-A8C0-C546D2016E67

Q34422105-4CE470DD-5465-49E4-A94B-CA383CED4672

Q34422105-55341E9D-63B3-4FF1-BCDF-3042EE78CC24

Q34422105-5BF39E3D-372B-4FCD-8B90-0A4F3BAA555C

Q34422105-89B7083B-0C14-4D0C-8AAA-10C5E60DF64D

Q34422105-9C702A14-F652-4251-8D1E-6F9135367792

Q34422105-9EF88762-BC6D-4E53-A983-6C09ED636316

Q34422105-AFB3E222-5C63-4CCF-8DF5-6F0E488A07B6

P304

Q34422105-0626141F-58AF-4835-95A9-DBBA3D47D700

P31

Q34422105-E4518285-F7E0-465B-BE71-091FD36CAD3B

P356

Q34422105-83266113-DCE7-4BAB-8702-DD025CA60287

P407

Q34422105-DC478B67-5C30-4A7A-9672-9E2DB01ADAAC

P433

Q34422105-110D0ED6-A396-4E05-B85A-604CC88A6334

P478

Q34422105-0FF7E71E-33AA-40E5-AA8D-7111EDF706E1

P577

Q34422105-6AF441B7-19F3-45B0-851C-CDE51A8396DB

P5875

Q34422105-75E5C326-75FB-4709-A1F2-1BBBA8B7D2C4

P698

Q34422105-73C57525-D12A-4085-AB61-57569E4F1EB9

P921

Q34422105-9D813B05-9C2A-4C0F-8862-621232DA8D3C

P932

Q34422105-484D63CA-EEA0-4093-BBF2-232295B8D1D9

P356

P1433

P1476

Glutathione synthesis is dimin ...... tion with cysteine and glycine

@en

P2093

Anuradha P Guthikonda

http://www.w3.org/2001/XMLSchema#string

Ashok Balasubramanyam

http://www.w3.org/2001/XMLSchema#string

Farook Jahoor

http://www.w3.org/2001/XMLSchema#string

Rajagopal V Sekhar

http://www.w3.org/2001/XMLSchema#string

Sanjeet G Patel

http://www.w3.org/2001/XMLSchema#string

Siripoom V McKay

http://www.w3.org/2001/XMLSchema#string

Vasumathi T Reddy

http://www.w3.org/2001/XMLSchema#string

P2860

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

Biochemistry and molecular cell biology of diabetic complications

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

The missing link: a single unifying mechanism for diabetic complications.

Methods for measuring glutathione concentration and rate of synthesis.

Synthesis of erythrocyte glutathione in healthy adults consuming the safe amount of dietary protein.

Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet.

Preliminary report: Amino acid profile in platelets of diabetic patients.

Antioxidant status and lipid peroxidation in type II diabetes mellitus.

P304

162-167

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.2337/DC10-1006

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

34

http://www.w3.org/2001/XMLSchema#string

P577

2010-10-07T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

47370111

http://www.w3.org/2001/XMLSchema#string

P698

20929994

http://www.w3.org/2001/XMLSchema#string

P921

P932

3005481

http://www.w3.org/2001/XMLSchema#string