DUF1220 protein domains drive proliferation in human neural stem cells and are associated with increased cortical volume in anthropoid primates.
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DUF1220 copy number is linearly associated with increased cognitive function as measured by total IQ and mathematical aptitude scoresReplicated linear association between DUF1220 copy number and severity of social impairment in autismDUF1220 copy number is associated with schizophrenia risk and severity: implications for understanding autism and schizophrenia as related diseasesNeocortex expansion is linked to size variations in gene families with chemotaxis, cell-cell signalling and immune response functions in mammalsThe case for DUF1220 domain dosage as a primary contributor to anthropoid brain expansion2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain SizeGeneration of mice lacking DUF1220 protein domains: effects on fecundity and hyperactivity.Morphological and functional aspects of progenitors perturbed in cortical malformations.High resolution measurement of DUF1220 domain copy number from whole genome sequence data.Evolution of the Human Nervous System Function, Structure, and Development.Phylogenetic Analysis Supports a Link between DUF1220 Domain Number and Primate Brain Expansion.Human accelerated regions and other human-specific sequence variations in the context of evolution and their relevance for brain development.Genomic trade-offs: are autism and schizophrenia the steep price of the human brain?Lineage divergence of activity-driven transcription and evolution of cognitive ability.A proposal to change the name of the NBPF/DUF1220 domain to the Olduvai domain.Enhancing our brains: Genomic mechanisms underlying cortical evolution.
P2860
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P2860
DUF1220 protein domains drive proliferation in human neural stem cells and are associated with increased cortical volume in anthropoid primates.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
DUF1220 protein domains drive ...... volume in anthropoid primates.
@ast
DUF1220 protein domains drive ...... volume in anthropoid primates.
@en
DUF1220 protein domains drive ...... volume in anthropoid primates.
@nl
type
label
DUF1220 protein domains drive ...... volume in anthropoid primates.
@ast
DUF1220 protein domains drive ...... volume in anthropoid primates.
@en
DUF1220 protein domains drive ...... volume in anthropoid primates.
@nl
prefLabel
DUF1220 protein domains drive ...... volume in anthropoid primates.
@ast
DUF1220 protein domains drive ...... volume in anthropoid primates.
@en
DUF1220 protein domains drive ...... volume in anthropoid primates.
@nl
P2093
P2860
P1476
DUF1220 protein domains drive ...... volume in anthropoid primates.
@en
P2093
B S Nielsen
J G Keeney
J M Sikela
J Siegenthaler
W D Hopkins
P2860
P304
P356
10.1007/S00429-014-0814-9
P577
2014-06-25T00:00:00Z