Extensive syncytium formation mediated by the reovirus FAST proteins triggers apoptosis-induced membrane instability
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Adenovirus-Mediated Expression of the p14 Fusion-Associated Small Transmembrane Protein Promotes Cancer Cell Fusion and Apoptosis In Vitro but Does Not Provide Therapeutic Efficacy in a Xenograft Mouse Model of CancerA compact, multifunctional fusion module directs cholesterol-dependent homomultimerization and syncytiogenic efficiency of reovirus p10 FAST proteinsA Virus-Encoded Cell–Cell Fusion Machine Dependent on Surrogate AdhesinsReovirus FAST Proteins Drive Pore Formation and Syncytiogenesis Using a Novel Helix-Loop-Helix Fusion-Inducing Lipid Packing SensorA library of mammalian effector modules for synthetic morphologyEnhanced fusion pore expansion mediated by the trans-acting Endodomain of the reovirus FAST proteins.Replication and Oncolytic Activity of an Avian Orthoreovirus in Human Hepatocellular Carcinoma Cells.Features of a spatially constrained cystine loop in the p10 FAST protein ectodomain define a new class of viral fusion peptides.Reovirus cell entry requires functional microtubules.Bioinformatics of recent aqua- and orthoreovirus isolates from fish: evolutionary gain or loss of FAST and fiber proteins and taxonomic implicationsReovirus FAST protein transmembrane domains function in a modular, primary sequence-independent manner to mediate cell-cell membrane fusion.Polybasic trafficking signal mediates golgi export, ER retention or ER export and retrieval based on membrane-proximityCell entry of avian reovirus follows a caveolin-1-mediated and dynamin-2-dependent endocytic pathway that requires activation of p38 mitogen-activated protein kinase (MAPK) and Src signaling pathways as well as microtubules and small GTPase Rab5 proWhole-Genome Analysis of a Novel Fish Reovirus (MsReV) Discloses Aquareovirus Genomic Structure Relationship with Host in Saline EnvironmentsMyxoma virus and oncolytic virotherapy: a new biologic weapon in the war against cancer.The p14 FAST protein of reptilian reovirus increases vesicular stomatitis virus neuropathogenesis.Membrane lysis during biological membrane fusion: collateral damage by misregulated fusion machines.Expression of the fusogenic p14 FAST protein from a replication-defective adenovirus vector does not provide a therapeutic benefit in an immunocompetent mouse model of cancer.Adenoviral Vectors Armed with Cell Fusion-Inducing Proteins as Anti-Cancer Agents.Golgi complex-plasma membrane trafficking directed by an autonomous, tribasic Golgi export signalReovirus-associated meningoencephalomyelitis in baboons.A critical role of LAMP-1 in avian reovirus P10 degradation associated with inhibition of apoptosis and virus release.Critical role of eukaryotic elongation factor 1 alpha 1 (EEF1A1) in avian reovirus sigma-C-induced apoptosis and inhibition of viral growth.Efficient reovirus- and measles virus-mediated pore expansion during syncytium formation is dependent on annexin A1 and intracellular calcium.Molecular characterization of avian reovirus isolates in TunisiaHelix-destabilizing, beta-branched, and polar residues in the baboon reovirus p15 transmembrane domain influence the modularity of FAST proteins.Open reading frame E3-10.9K of subspecies B1 human adenoviruses encodes a family of late orthologous proteins that vary in their predicted structural features and subcellular localization.Facilitated leaky scanning and atypical ribosome shunting direct downstream translation initiation on the tricistronic S1 mRNA of avian reovirus.Aquareovirus effects syncytiogenesis by using a novel member of the FAST protein family translated from a noncanonical translation start site.Reovirus FAST Protein Enhances Vesicular Stomatitis Virus Oncolytic Virotherapy in Primary and Metastatic Tumor Models.Proteomics informed by transcriptomics for characterising differential cellular susceptibility to Nelson Bay orthoreovirus infection.Entirely plasmid-based reverse genetics system for rotaviruses.A new aquareovirus causing high mortality in farmed Atlantic halibut fry in Norway.Lysophosphatidylcholine reversibly arrests pore expansion during syncytium formation mediated by diverse viral fusogens.Multifaceted sequence-dependent and -independent roles for reovirus FAST protein cytoplasmic tails in fusion pore formation and syncytiogenesis.Transcriptome analysis of avian reovirus-mediated changes in gene expression of normal chicken fibroblast DF-1 cells.The E3 ubiquitin ligase Siah-1 suppresses avian reovirus infection by targeting p10 for degradation.Fusogenic Viruses in Oncolytic Immunotherapy
P2860
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P2860
Extensive syncytium formation mediated by the reovirus FAST proteins triggers apoptosis-induced membrane instability
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Extensive syncytium formation ...... s-induced membrane instability
@ast
Extensive syncytium formation ...... s-induced membrane instability
@en
Extensive syncytium formation ...... s-induced membrane instability
@nl
type
label
Extensive syncytium formation ...... s-induced membrane instability
@ast
Extensive syncytium formation ...... s-induced membrane instability
@en
Extensive syncytium formation ...... s-induced membrane instability
@nl
prefLabel
Extensive syncytium formation ...... s-induced membrane instability
@ast
Extensive syncytium formation ...... s-induced membrane instability
@en
Extensive syncytium formation ...... s-induced membrane instability
@nl
P2093
P2860
P1433
P1476
Extensive syncytium formation ...... s-induced membrane instability
@en
P2093
Jayme Salsman
Julie Boutilier
Roy Duncan
P2860
P304
P356
10.1128/JVI.79.13.8090-8100.2005
P407
P577
2005-07-01T00:00:00Z