Reversal of DNA alkylation damage by two human dioxygenases. - Wikidata - awgldk - TriplyDB

Reversal of DNA alkylation damage by two human dioxygenases.

Reversal of DNA alkylation damage by two human dioxygenases.

http://www.wikidata.org/entity/Q34429515

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The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia Smoking induces long-lasting effects through a monoamine-oxidase epigenetic regulation ALKBH4-dependent demethylation of actin regulates actomyosin dynamics.DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation Crystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO Spectroscopic and magnetic studies of wild-type and mutant forms of the Fe(II)- and 2-oxoglutarate-dependent decarboxylase ALKBH4 Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA Human AlkB homologue 1 (ABH1) exhibits DNA lyase activity at abasic sites Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α)ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis Polyamines stimulate the formation of mutagenic 1,N2-propanodeoxyguanosine adducts from acetaldehyde Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli Molecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systems A non-heme iron-mediated chemical demethylation in DNA and RNA The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA Vitamin C: update on physiology and pharmacology Alleviation of 1,N6-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkB Phylogenomic identification of five new human homologs of the DNA repair enzyme AlkB Ascorbate depletion: a critical step in nickel carcinogenesis?The current state of eukaryotic DNA base damage and repair Structural basis for enzymatic excision of N1-methyladenine and N3-methylcytosine from DNA Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system Implications for Damage Recognition during Dpo4-Mediated Mutagenic Bypass of m1G and m3C Lesions The Fe(II)/α-ketoglutarate-dependent taurine dioxygenases from Pseudomonas putida and Escherichia coli are tetramers Duplex interrogation by a direct DNA repair protein in search of base damage Origin of the Proton-transfer Step in the Cofactor-free (1H)-3-Hydroxy-4-oxoquinaldine 2,4-Dioxygenase: EFFECT OF THE BASICITY OF AN ACTIVE SITE HIS RESIDUE Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-stranded N 6 -Methyladenosine RNA Demethylation Switching demethylation activities between AlkB family RNA/DNA demethylases through exchange of active-site residues A role for Saccharomyces cerevisiae Tpa1 protein in direct alkylation repair Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo A covalent protein-DNA 5'-product adduct is generated following AP lyase activity of human ALKBH1 (AlkB homologue 1)

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Reversal of DNA alkylation damage by two human dioxygenases.

http://www.wikidata.org/entity/Q34429515

description

2002 nî lūn-bûn

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2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

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2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

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2002年論文

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2002年论文

@wuu

name

Reversal of DNA alkylation damage by two human dioxygenases.

@ast

Reversal of DNA alkylation damage by two human dioxygenases.

@en

Reversal of DNA alkylation damage by two human dioxygenases.

@nl

type

label

Reversal of DNA alkylation damage by two human dioxygenases.

@ast

Reversal of DNA alkylation damage by two human dioxygenases.

@en

Reversal of DNA alkylation damage by two human dioxygenases.

@nl

prefLabel

Reversal of DNA alkylation damage by two human dioxygenases.

@ast

Reversal of DNA alkylation damage by two human dioxygenases.

@en

Reversal of DNA alkylation damage by two human dioxygenases.

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Reversal of DNA alkylation damage by two human dioxygenases.

@en

P2093

Barbara Sedgwick

http://www.w3.org/2001/XMLSchema#string

Pertti Koivisto

http://www.w3.org/2001/XMLSchema#string

Sarah C Trewick

http://www.w3.org/2001/XMLSchema#string

Tod Duncan

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P2860

Conserved domains in DNA repair proteins and evolution of repair systems

Defective processing of methylated single-stranded DNA by E. coli AlkB mutants

The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases

Kinetic and crystallographic studies on deacetoxycephalosporin C synthase (DAOCS)

Structure and mechanism of anthocyanidin synthase from Arabidopsis thaliana

Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes

Protein secondary structure prediction based on position-specific scoring matrices

Molecular cloning and functional analysis of a human cDNA encoding an Escherichia coli AlkB homolog, a protein involved in DNA alkylation damage repair

Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue

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16660-16665

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scholarly article

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10.1073/PNAS.262589799

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26

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99

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2002-12-16T00:00:00Z

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10987678

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12486230

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139200

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