Testing efficacy of administration of the antiaging drug rapamycin in a nonhuman primate, the common marmoset. - Wikidata - awgldk - TriplyDB

Testing efficacy of administration of the antiaging drug rapamycin in a nonhuman primate, the common marmoset.

Testing efficacy of administration of the antiaging drug rapamycin in a nonhuman primate, the common marmoset.

http://www.wikidata.org/entity/Q34429764

about

Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative Diseases Inhibition of the Mechanistic Target of Rapamycin (mTOR)-Rapamycin and Beyond The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus)Pharmaceutical inhibition of mTOR in the common marmoset: effect of rapamycin on regulators of proteostasis in a non-human primate Can aging be 'drugged'?mTOR drives cerebral blood flow and memory deficits in LDLR(-/-) mice modeling atherosclerosis and vascular cognitive impairment.Non-human primates as a model for aging.Meta-Analysis of 29 Experiments Evaluating the Effects of Rapamycin on Life Span in the Laboratory Mouse.Immune-Stimulatory Effects of Rapamycin Are Mediated by Stimulation of Antitumor γδ T Cells.mTORC1/2 inhibition preserves ovarian function and fertility during genotoxic chemotherapy.Moving toward 'common' use of the marmoset as a non-human primate aging model.The development of a specific pathogen free (SPF) barrier colony of marmosets (Callithrix jacchus) for aging research.Marmoset cytochrome P450 2J2 mainly expressed in small intestines and livers effectively metabolizes human P450 2J2 probe substrates, astemizole and terfenadine.A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: Immunological, physical performance, and cognitive effects.Metformin reduces glucose intolerance caused by rapamycin treatment in genetically heterogeneous female mice.A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs.

P2860

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P2860

Testing efficacy of administration of the antiaging drug rapamycin in a nonhuman primate, the common marmoset.

http://www.wikidata.org/entity/Q34429764

description

2014 nî lūn-bûn

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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2014 թվականի հուլիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Testing efficacy of administra ...... primate, the common marmoset.

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P1433

The Journals of Gerontology

P1476

Testing efficacy of administra ...... primate, the common marmoset.

@en

P2093

Adam Salmon

http://www.w3.org/2001/XMLSchema#string

Arlan Richardson

http://www.w3.org/2001/XMLSchema#string

Corinna Ross

http://www.w3.org/2001/XMLSchema#string

Elizabeth Fernandez

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Jennifer Spross

http://www.w3.org/2001/XMLSchema#string

Marty Javors

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Phillip Bergman

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Randy Strong

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Suzette Tardif

http://www.w3.org/2001/XMLSchema#string

P2860

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome

The marmoset as a model of aging and age-related diseases.

Rapamycin extends murine lifespan but has limited effects on aging.

Aging biology and novel targets for drug discovery.

Rapamycin extends life and health in C57BL/6 mice

Rapamycin slows aging in mice

Differential contribution of dietary fat and monosaccharide to metabolic syndrome in the common marmoset (Callithrix jacchus)

P304

577-587

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scholarly article

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10.1093/GERONA/GLU101

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5

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70

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2014-07-19T00:00:00Z

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264057071

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25038772

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4400395

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