Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
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Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpretedA δ38 deletion variant of human transketolase as a model of transketolase-like protein 1 exhibits no enzymatic activityEmerging Role of the Pentose Phosphate Pathway in Hepatocellular Carcinoma.TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilizationLactate-dehydrogenase 5 is overexpressed in non-small cell lung cancer and correlates with the expression of the transketolase-like protein 1Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy.Transketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formationTp53-induced glycolysis and apoptosis regulator (TIGAR) protects glioma cells from starvation-induced cell death by up-regulating respiration and improving cellular redox homeostasisA biomarker based detection and characterization of carcinomas exploiting two fundamental biophysical mechanisms in mammalian cellsGrowth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides.The molecular determinants of de novo nucleotide biosynthesis in cancer cellsLevels of certain tumor markers as differential factors between bilharzial and non-biharzial bladder cancer among Egyptian patients.Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours.Oral cancer cells may rewire alternative metabolic pathways to survive from siRNA silencing of metabolic enzymes.TKTL1 expression in human malign and benign cell lines.Transketolase-like 1 ectopic expression is associated with DNA hypomethylation and induces the Warburg effect in melanoma cells.The impact of thiamine treatment in the diabetes mellitus.The development of tumours under a ketogenic diet in association with the novel tumour marker TKTL1: A case series in general practice.Transketolase-like protein 1 expression predicts poor prognosis in colorectal cancer.Statistical analysis of pentose phosphate pathway genes from eubacteria and eukarya reveals translational selection as a major force in shaping codon usage pattern.Overexpression of transketolase-like gene 1 is associated with cell proliferation in uterine cervix cancer.Expression of p-AKT characterizes adenoid cystic carcinomas of head and neck with a higher risk for tumor relapses.A key role for transketolase-like 1 in tumor metabolic reprogramming.Metabolism and brain cancer.Brain and behavioral pathology in an animal model of Wernicke's encephalopathy and Wernicke-Korsakoff Syndrome.The pentose phosphate pathway and cancer.Role of HIF-1α in the hypoxia inducible expression of the thiamine transporter, SLC19A3.EDIM-TKTL1/Apo10 Blood Test: An Innate Immune System Based Liquid Biopsy for the Early Detection, Characterization and Targeted Treatment of Cancer.Evaluation of TKTL1 as a biomarker in serum of prostate cancer patients.The role of glucose metabolism and glucose-associated signalling in cancer.Elevated activity of the oxidative and non-oxidative pentose phosphate pathway in (pre)neoplastic lesions in rat liver.Effect of siRNA-mediated gene silencing of transketolase on A549 lung cancer cells.d-Ribose as a Contributor to Glycated Haemoglobin.Gene Expression Profiling of Multiple Sclerosis Pathology Identifies Early Patterns of Demyelination Surrounding Chronic Active Lesions.Glucose transporter-1 as an independent prognostic marker for cancer: a meta-analysis.Evidence for transketolase-like TKTL1 flux in CHO cells based on parallel labeling experiments and (13)C-metabolic flux analysis.A guide to 13C metabolic flux analysis for the cancer biologist.p53 and metabolism: from mechanism to therapeutics.
P2860
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P2860
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Mutations in the transketolase ...... diseases, diabetes and cancer.
@ast
Mutations in the transketolase ...... diseases, diabetes and cancer.
@en
Mutations in the transketolase ...... diseases, diabetes and cancer.
@nl
type
label
Mutations in the transketolase ...... diseases, diabetes and cancer.
@ast
Mutations in the transketolase ...... diseases, diabetes and cancer.
@en
Mutations in the transketolase ...... diseases, diabetes and cancer.
@nl
prefLabel
Mutations in the transketolase ...... diseases, diabetes and cancer.
@ast
Mutations in the transketolase ...... diseases, diabetes and cancer.
@en
Mutations in the transketolase ...... diseases, diabetes and cancer.
@nl
P2093
P1433
P1476
Mutations in the transketolase ...... diseases, diabetes and cancer.
@en
P2093
Dirk Dressler
Johannes F Coy
Juergen Wilde
Peter Schubert
P304
P577
2005-01-01T00:00:00Z