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Dihydrofolate reductase as a model for studies of enzyme dynamics and catalysisConnecting Active-Site Loop Conformations and Catalysis in Triosephosphate Isomerase: Insights from a Rare Variation at Residue 96 in the Plasmodial EnzymeThe role of protein dynamics in the evolution of new enzyme functionPromiscuity in the Enzymatic Catalysis of Phosphate and Sulfate Transfer.Preserved hydride transfer mechanism in evolutionarily divergent thymidylate synthases.Introduction to the thematic minireview series on enzyme evolution.Role of Conformational Dynamics in the Evolution of Retro-Aldolase Activity.Contribution of Buried Distal Amino Acid Residues in Horse Liver Alcohol Dehydrogenase to Structure and Catalysis.Relaxation of nonproductive binding and increased rate of coenzyme release in an alcohol dehydrogenase increases turnover with a nonpreferred alcohol enantiomer.Kinetics of low-temperature transitions and a reaction rate theory from non-equilibrium distributions.Enzymatic Kinetic Isotope Effects from Path-Integral Free Energy Perturbation Theory.Isotope Substitution of Promiscuous Alcohol Dehydrogenase Reveals the Origin of Substrate Preference in the Transition State.Rescue of conformational dynamics in enzyme catalysis by directed evolution.Linking coupled motions and entropic effects to the catalytic activity of 2-deoxyribose-5-phosphate aldolase (DERA)† †Electronic supplementary information (ESI) available: Further experimental and computational data. See DOI: 10.1039/c5sc03666f.Minimization of dynamic effects in the evolution of dihydrofolate reductase† †Electronic supplementary information (ESI) available: Full experimental procedures; mass spectra of purified proteins; circular dichroism spectra, tabulated experimental d
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Evolutionary aspects of enzyme dynamics
@ast
Evolutionary aspects of enzyme dynamics
@en
Evolutionary aspects of enzyme dynamics
@nl
type
label
Evolutionary aspects of enzyme dynamics
@ast
Evolutionary aspects of enzyme dynamics
@en
Evolutionary aspects of enzyme dynamics
@nl
prefLabel
Evolutionary aspects of enzyme dynamics
@ast
Evolutionary aspects of enzyme dynamics
@en
Evolutionary aspects of enzyme dynamics
@nl
P2860
P356
P1476
Evolutionary aspects of enzyme dynamics
@en
P2093
Amnon Kohen
Judith P Klinman
P2860
P304
30205-30212
P356
10.1074/JBC.R114.565515
P407
P577
2014-09-10T00:00:00Z