Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.
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An unusual carbon-carbon bond cleavage reaction during phosphinothricin biosynthesisSynthesis of methylphosphonic acid by marine microbes: a source for methane in the aerobic oceanPurification and characterization of the epoxidase catalyzing the formation of fosfomycin from Pseudomonas syringaeDetermination of the substrate binding mode to the active site iron of (S)-2-hydroxypropylphosphonic acid epoxidase using 17O-enriched substrates and substrate analoguesStructural Basis of Regiospecificity of a Mononuclear Iron Enzyme in Antibiotic Fosfomycin BiosynthesisFlavin-Induced Oligomerization in Escherichia coli Adaptive Response Protein AidBMechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reactionDapdiamides, tripeptide antibiotics formed by unconventional amide ligases.Biosynthesis of rhizocticins, antifungal phosphonate oligopeptides produced by Bacillus subtilis ATCC6633Evidence that the fosfomycin-producing epoxidase, HppE, is a non-heme-iron peroxidaseSubstrate activation by iron superoxo intermediates.Structure and mechanism of enzymes involved in biosynthesis and breakdown of the phosphonates fosfomycin, dehydrophos, and phosphinothricin.In vivo self-hydroxylation of an iron-substituted manganese-dependent extradiol cleaving catechol dioxygenase.Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.Different biosynthetic pathways to fosfomycin in Pseudomonas syringae and Streptomyces species.Axial and equatorial ligand effects on biomimetic cysteine dioxygenase model complexesMechanistic investigation of methylphosphonate synthase, a non-heme iron-dependent oxygenase.Evidence for radical-mediated catalysis by HppE: a study using cyclopropyl and methylenecyclopropyl substrate analoguesRings, radicals, and regeneration: the early years of a bioorganic laboratoryBiosynthesis of fosfomycin, re-examination and re-confirmation of a unique Fe(II)- and NAD(P)H-dependent epoxidation reaction.Phosphonate biosynthesis and catabolism: a treasure trove of unusual enzymology.Reaction of HppE with substrate analogues: evidence for carbon-phosphorus bond cleavage by a carbocation rearrangement.Biosynthesis of phosphonic and phosphinic acid natural products.Hydroperoxylation by hydroxyethylphosphonate dioxygenase.Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads.First- and second-sphere contributions to Fe(II) site activation by cosubstrate binding in non-heme Fe enzymes.Beyond ferryl-mediated hydroxylation: 40 years of the rebound mechanism and C-H activation.Mechanistic consequences of chiral radical clock probes: analysis of the mononuclear non-heme iron enzyme HppE with 2-hydroxy-3-methylenecyclopropyl radical clock substrates.Go it alone: four-electron oxidations by mononuclear non-heme iron enzymes.Dioxygen activation by nonheme iron enzymes with the 2-His-1-carboxylate facial triad that generate high-valent oxoiron oxidants.Bacillus anthracis Prolyl 4-Hydroxylase Interacts with and Modifies Elongation Factor Tu.Regio- and stereodivergent antibiotic oxidative carbocyclizations catalysed by Rieske oxygenase-like enzymes.On the catalytic mechanism of (S)-2-hydroxypropylphosphonic acid epoxidase (HppE): a hybrid DFT study.How Are Substrate Binding and Catalysis Affected by Mutating Glu127 and Arg161 in Prolyl-4-hydroxylase? A QM/MM and MD Study.Biochemistry: Positive and radical.Structural basis for methylphosphonate biosynthesis.Engineering Styrene Monooxygenase for Biocatalysis: Reductase-Epoxidase Fusion Proteins.Natural products as inspiration for the development of new synthetic methods.
P2860
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P2860
Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.
@ast
Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.
@en
Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.
@nl
type
label
Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.
@ast
Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.
@en
Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.
@nl
prefLabel
Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.
@ast
Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.
@en
Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.
@nl
P2093
P2860
P356
P1433
P1476
Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.
@en
P2093
Catherine L Drennan
Hung-wen Liu
Luke J Higgins
Pinghua Liu
P2860
P2888
P304
P356
10.1038/NATURE03924
P407
P577
2005-07-13T00:00:00Z
P6179
1005542817