Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats.
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The mGluR2 positive allosteric modulator BINA decreases cocaine self-administration and cue-induced cocaine-seeking and counteracts cocaine-induced enhancement of brain reward function in ratsGlutamatergic substrates of drug addiction and alcoholismmGluR5 antagonism attenuates methamphetamine reinforcement and prevents reinstatement of methamphetamine-seeking behavior in ratsDissociation of the effects of MTEP [3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]piperidine] on conditioned reinstatement and reinforcement: comparison between cocaine and a conventional reinforcerNegative Allosteric Modulators of Metabotropic Glutamate Receptors Subtype 5 in Addiction: a Therapeutic WindowThe "stop" and "go" of nicotine dependence: role of GABA and glutamateRole of cues and contexts on drug-seeking behaviourMetabotropic Glutamate Receptor 7 (mGluR7) as a Target for the Treatment of Psychostimulant DependenceThe metabotropic glutamate 5 receptor modulates extinction and reinstatement of methamphetamine-seeking in miceMetabotropic glutamate receptors: from the workbench to the bedside.The neuropharmacology of relapse to food seeking: methodology, main findings, and comparison with relapse to drug seeking.Homers regulate drug-induced neuroplasticity: implications for addictionProgressive and lasting amplification of accumbal nicotine-seeking neural signalsInvolvement of metabotropic glutamate receptor 5 in brain reward deficits associated with cocaine and nicotine withdrawal and somatic signs of nicotine withdrawal.Cue-conditioned alcohol seeking in rats following abstinence: involvement of metabotropic glutamate 5 receptors.Interoceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbensMetabotropic glutamate receptor 5 activity in the nucleus accumbens is required for the maintenance of ethanol self-administration in a rat genetic model of high alcohol intakeEffects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependenceCognitive effects of Group I metabotropic glutamate receptor ligands in the context of drug addiction.Neurobiological mechanisms involved in nicotine dependence and reward: participation of the endogenous opioid system.Acute effects of nicotine amplify accumbal neural responses during nicotine-taking behavior and nicotine-paired environmental cues.Potential substrates for nicotine and alcohol interactions: a focus on the mesocorticolimbic dopamine system.Targeting glutamate homeostasis for potential treatment of nicotine dependence.The metabotropic glutamate 5 receptor is necessary for extinction of cocaine-associated cues.Blockade of mGluR5 in the nucleus accumbens shell but not core attenuates heroin seeking behavior in rats.D-cycloserine selectively decreases nicotine self-administration in rats with low baseline levels of response.Alcohol-seeking behavior is associated with increased glutamate transmission in basolateral amygdala and nucleus accumbens as measured by glutamate-oxidase-coated biosensors.Repeated administration of the GABAB receptor positive modulator BHF177 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine seeking in ratsEffects of mGluR1 antagonism in the dorsal hippocampus on drug context-induced reinstatement of cocaine-seeking behavior in rats.Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in ratsIntravenous nicotine injection induces rapid, experience-dependent sensitization of glutamate release in the ventral tegmental area and nucleus accumbensmGlu receptors and drug addiction.Galantamine, an acetylcholinesterase inhibitor and positive allosteric modulator of nicotinic acetylcholine receptors, attenuates nicotine taking and seeking in ratsMarked global reduction in mGluR5 receptor binding in smokers and ex-smokers determined by [11C]ABP688 positron emission tomographyEffects of mGlu1-receptor blockade on ethanol self-administration in inbred alcohol-preferring rats.Development of novel pharmacotherapeutics for tobacco dependence: progress and future directionsN-acetylcysteine decreased nicotine self-administration and cue-induced reinstatement of nicotine seeking in rats: comparison with the effects of N-acetylcysteine on food responding and food seekingDeficits in ventromedial prefrontal cortex group 1 metabotropic glutamate receptor function mediate resistance to extinction during protracted withdrawal from an extensive history of cocaine self-administrationMechanism-based medication development for the treatment of nicotine dependence.Review. Neurobiology of nicotine dependence.
P2860
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P2860
Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Metabotropic glutamate recepto ...... ministration behavior in rats.
@ast
Metabotropic glutamate recepto ...... ministration behavior in rats.
@en
Metabotropic glutamate receptor
@nl
type
label
Metabotropic glutamate recepto ...... ministration behavior in rats.
@ast
Metabotropic glutamate recepto ...... ministration behavior in rats.
@en
Metabotropic glutamate receptor
@nl
prefLabel
Metabotropic glutamate recepto ...... ministration behavior in rats.
@ast
Metabotropic glutamate recepto ...... ministration behavior in rats.
@en
Metabotropic glutamate receptor
@nl
P2093
P50
P1433
P1476
Metabotropic glutamate recepto ...... dministration behavior in rats
@en
P2093
Athina Markou
Edwin Zvartau
Elena Blokhina
Elena Zakharova
Gino van Heeke
Wojciech Danysz
P304
P356
10.1016/J.NEUROPHARM.2005.06.007
P478
49 Suppl 1
P577
2005-01-01T00:00:00Z