Translocations of the RARalpha gene in acute promyelocytic leukemia. - Wikidata - awgldk - TriplyDB

Translocations of the RARalpha gene in acute promyelocytic leukemia.

Translocations of the RARalpha gene in acute promyelocytic leukemia.

http://www.wikidata.org/entity/Q34435522

about

Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization Flow cytometric immunobead assay for fast and easy detection of PML-RARA fusion proteins for the diagnosis of acute promyelocytic leukemia The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions Epimutational profile of hematologic malignancies as attractive target for new epigenetic therapies Disruption of retinoic acid receptor alpha reveals the growth promoter face of retinoic acid Hic-5 regulates an epithelial program mediated by PPARgamma Genetic tests to evaluate prognosis and predict therapeutic response in acute myeloid leukemia.A feedback loop mediated by degradation of an inhibitor is required to initiate neuronal differentiation.Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein.Smooth muscle α-actin is a direct target of PLZF: effects on the cytoskeleton and on susceptibility to oncogenic transformation.ESRRA-C11orf20 is a recurrent gene fusion in serous ovarian carcinoma.The dynamic organization of gene-regulatory machinery in nuclear microenvironments ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex.Histone Deacetylase Inhibitors: Advancing Therapeutic Strategies in Hematological and Solid Malignancies.Dominant negative retinoic acid receptor initiates tumor formation in mice.The emergence of resistance to targeted cancer therapeutics.Growth suppression by acute promyelocytic leukemia-associated protein PLZF is mediated by repression of c-myc expression Molecular cytogenetic characterization of Sézary syndrome.Active repression by unliganded retinoid receptors in development: less is sometimes more PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway.Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.Retinoids in cancer therapy and chemoprevention: promise meets resistance.Targeting expression of the leukemogenic PML-RARα fusion protein by lentiviral vector-mediated small interfering RNA results in leukemic cell differentiation and apoptosis Effects of all-trans retinoic acid (ATRA) on human myeloma cells.Hematopoiesis and retinoids: development and disease.A closer look at specific therapeutic strategies in leukemia.RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells.Roles of retinoids and retinoic Acid receptors in the regulation of hematopoietic stem cell self-renewal and differentiation.PML-retinoic acid receptor alpha inhibits PML IV enhancement of PU.1-induced C/EBPepsilon expression in myeloid differentiation.Aberrant chromatin remodeling by retinoic acid receptor alpha fusion proteins assessed at the single-cell level Nucleocytoplasmic transport in apoptosis.In vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia.Control of viral infectivity by tripartite motif proteins.Activated polymorphonuclear leukocytes rapidly synthesize retinoic acid receptor-alpha: a mechanism for translational control of transcriptional events.The genetics of the myelodysplastic syndromes: classical cytogenetics and recent molecular insights.Retinoic acid modulates chromatin to potentiate tumor necrosis factor alpha signaling on the DIF2 promoter Nucleophosmin: a versatile molecule associated with hematological malignancies.8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RARα degradation.Molecular mechanisms of drug resistance in acute myeloid leukaemia.Large-scale identification of disease genes involved in acute myeloid leukemia

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P2860

Translocations of the RARalpha gene in acute promyelocytic leukemia.

http://www.wikidata.org/entity/Q34435522

description

2001 nî lūn-bûn

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2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Translocations of the RARalpha gene in acute promyelocytic leukemia.

@ast

Translocations of the RARalpha gene in acute promyelocytic leukemia.

@en

Translocations of the RARalpha gene in acute promyelocytic leukemia.

@nl

type

label

Translocations of the RARalpha gene in acute promyelocytic leukemia.

@ast

Translocations of the RARalpha gene in acute promyelocytic leukemia.

@en

Translocations of the RARalpha gene in acute promyelocytic leukemia.

@nl

prefLabel

Translocations of the RARalpha gene in acute promyelocytic leukemia.

@ast

Translocations of the RARalpha gene in acute promyelocytic leukemia.

@en

Translocations of the RARalpha gene in acute promyelocytic leukemia.

@nl

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Translocations of the RARalpha gene in acute promyelocytic leukemia.

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A Melnick

http://www.w3.org/2001/XMLSchema#string

A Zelent

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F Guidez

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J D Licht

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P2860

Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling

Crystal structure of the BTB domain from PLZF

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

GAS41, a highly conserved protein in eukaryotic nuclei, binds to NuMA

Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

Regulation of p53 activity in nuclear bodies by a specific PML isoform

Developmentally regulated expression of a human "finger"-containing gene encoded by the 5' half of the ret transforming gene

Human-specific nuclear protein that associates with the polar region of the mitotic apparatus: distribution in a human/hamster hybrid cell

NuMA: an unusually long coiled-coil related protein in the mammalian nucleus

Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis

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20

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