Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation. - Wikidata - awgldk - TriplyDB

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

http://www.wikidata.org/entity/Q34436638

about

"Off-Spotter": very fast and exhaustive enumeration of genomic lookalikes for designing CRISPR/Cas guide RNAs The Rise of CRISPR/Cas for Genome Editing in Stem Cells Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing Rendering the Intractable More Tractable: Tools from Caenorhabditis elegans Ripe for Import into Parasitic Nematodes Targeting Non-Coding RNAs in Plants with the CRISPR-Cas Technology is a Challenge yet Worth Accepting Resources for the design of CRISPR gene editing experiments How specific is CRISPR/Cas9 really?Minimizing off-Target Mutagenesis Risks Caused by Programmable Nucleases A new age in functional genomics using CRISPR/Cas9 in arrayed library screening Enabling functional genomics with genome engineering The New State of the Art: Cas9 for Gene Activation and Repression Designed nucleases for targeted genome editing Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference Off-target Effects in CRISPR/Cas9-mediated Genome Engineering Quantifying on- and off-target genome editing Genetic screens and functional genomics using CRISPR/Cas9 technology Synthetic RNAs for Gene Regulation: Design Principles and Computational Tools Discovery of a proteinaceous cellular receptor for a norovirus Patterns of CRISPR/Cas9 activity in plants, animals and microbes Engineering Sugar Utilization and Microbial Tolerance toward Lignocellulose Conversion CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections Genomic Characterization of Metformin Hepatic Response Genome engineering in the yeast pathogen Candida glabrata using the CRISPR-Cas9 system BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis Structure Principles of CRISPR-Cas Surveillance and Effector Complexes Editing of the urease gene by CRISPR-Cas in the diatom Thalassiosira pseudonana Integrated genetic and pharmacologic interrogation of rare cancers CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins.High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9.CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.Generating Mouse Models Using CRISPR-Cas9-Mediated Genome Editing.CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis CRISPR/Cas9: Transcending the Reality of Genome Editing.Reliable CRISPR/Cas9 Genome Engineering in Caenorhabditis elegans Using a Single Efficient sgRNA and an Easily Recognizable Phenotype.Generation of heritable germline mutations in the jewel wasp Nasonia vitripennis using CRISPR/Cas9 The CRISPR/Cas9 system efficiently reverts the tumorigenic ability of BCR/ABL in vitro and in a xenograft model of chronic myeloid leukemia.pKAMA-ITACHI Vectors for Highly Efficient CRISPR/Cas9-Mediated Gene Knockout in Arabidopsis thaliana.CRISPR/Cas9: From Genome Engineering to Cancer Drug Discovery Flexible CRISPR library construction using parallel oligonucleotide retrieval.

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Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

http://www.wikidata.org/entity/Q34436638

description

2014 nî lūn-bûn

@nan

2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

@ast

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

@en

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

@nl

type

label

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

@ast

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

@en

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

@nl

prefLabel

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

@ast

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

@en

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

@nl

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Nature Biotechnology

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Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation

@en

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Benjamin L Ebert

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Daniel B Graham

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David E Root

http://www.w3.org/2001/XMLSchema#string

Ella Hartenian

http://www.w3.org/2001/XMLSchema#string

Ian Smith

http://www.w3.org/2001/XMLSchema#string

John G Doench

http://www.w3.org/2001/XMLSchema#string

Ramnik J Xavier

http://www.w3.org/2001/XMLSchema#string

Zuzana Tothova

http://www.w3.org/2001/XMLSchema#string

P2860

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

RNA-guided human genome engineering via Cas9

Multiplex genome engineering using CRISPR/Cas systems

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

RNA-programmed genome editing in human cells

The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

Rational siRNA design for RNA interference

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1262-1267

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scholarly article

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10.1038/NBT.3026

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12

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32

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Meagan E Sullender

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2014-09-03T00:00:00Z

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265342515

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25184501

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4262738

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