Nicotine up-regulates alpha4beta2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning
about
Emerging preclinical pharmacological targets for Parkinson's diseasePharmacological chaperoning: a primer on mechanism and pharmacologyInside-out neuropharmacology of nicotinic drugsCornichons control ER export of AMPA receptors to regulate synaptic excitability.Mechanisms of inhibition and potentiation of α4β2 nicotinic acetylcholine receptors by members of the Ly6 protein familyLooking below the surface of nicotinic acetylcholine receptorsNicotine withdrawal.Identification and characterization of poly(I:C)-induced molecular responses attenuated by nicotine in mouse macrophages.Insights into the neurobiology of the nicotinic cholinergic system and nicotine addiction from mice expressing nicotinic receptors harboring gain-of-function mutationsFunctional expression of human α9* nicotinic acetylcholine receptors in X. laevis oocytes is dependent on the α9 subunit 5' UTR.Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors.Minireview: the intimate link between calcium sensing receptor trafficking and signaling: implications for disorders of calcium homeostasis.Mutations in the main cytoplasmic loop of the GABA(A) receptor α4 and δ subunits have opposite effects on surface expression.Using pharmacological chaperones to restore proteostasisDifferential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenulaProgress and challenges in the study of α6-containing nicotinic acetylcholine receptors.The duplicated α7 subunits assemble and form functional nicotinic receptors with the full-length α7.Biosynthesis of ionotropic acetylcholine receptors requires the evolutionarily conserved ER membrane complex.Lynx1 shifts α4β2 nicotinic receptor subunit stoichiometry by affecting assembly in the endoplasmic reticulum.Targeting glutamate homeostasis for potential treatment of nicotine dependence.Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward.miRNAome analysis of the mammalian neuronal nicotinic acetylcholine receptor gene family.RIC-3 differentially modulates α4β2 and α7 nicotinic receptor assembly, expression, and nicotine-induced receptor upregulationTranscriptional regulation by nicotine in dopaminergic neurons.Ly6h regulates trafficking of alpha7 nicotinic acetylcholine receptors and nicotine-induced potentiation of glutamatergic signaling.Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus.Characterizing functional α6β2 nicotinic acetylcholine receptors in vitro: mutant β2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells.Effects of chronic nicotine on heteromeric neuronal nicotinic receptors in rat primary cultured neurons.Trafficking of alpha4* nicotinic receptors revealed by superecliptic phluorin: effects of a beta4 amyotrophic lateral sclerosis-associated mutation and chronic exposure to nicotineEndogenously expressed muscarinic receptors in HEK293 cells augment up-regulation of stably expressed α4β2 nicotinic receptors.Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses.Use of concatemers of ligand-gated ion channel subunits to study mechanisms of steroid potentiation.Neuronal gamma-aminobutyric acid (GABA) type A receptors undergo cognate ligand chaperoning in the endoplasmic reticulum by endogenous GABA.Introduced Amino Terminal Epitopes Can Reduce Surface Expression of Neuronal Nicotinic Receptors.Pharmacological chaperoning of nicotinic acetylcholine receptors reduces the endoplasmic reticulum stress response.Live-cell imaging of single receptor composition using zero-mode waveguide nanostructures.Functional Upregulation of α4* Nicotinic Acetylcholine Receptors in VTA GABAergic Neurons Increases Sensitivity to Nicotine RewardThe nicotine metabolite, cotinine, alters the assembly and trafficking of a subset of nicotinic acetylcholine receptors.Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictionsFörster resonance energy transfer (FRET) correlates of altered subunit stoichiometry in cys-loop receptors, exemplified by nicotinic α4β2.
P2860
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P2860
Nicotine up-regulates alpha4beta2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Nicotine up-regulates alpha4be ...... hiometry-dependent chaperoning
@ast
Nicotine up-regulates alpha4be ...... hiometry-dependent chaperoning
@en
Nicotine up-regulates alpha4be ...... hiometry-dependent chaperoning
@nl
type
label
Nicotine up-regulates alpha4be ...... hiometry-dependent chaperoning
@ast
Nicotine up-regulates alpha4be ...... hiometry-dependent chaperoning
@en
Nicotine up-regulates alpha4be ...... hiometry-dependent chaperoning
@nl
prefLabel
Nicotine up-regulates alpha4be ...... hiometry-dependent chaperoning
@ast
Nicotine up-regulates alpha4be ...... hiometry-dependent chaperoning
@en
Nicotine up-regulates alpha4be ...... hiometry-dependent chaperoning
@nl
P2093
P2860
P50
P356
P1476
Nicotine up-regulates alpha4be ...... hiometry-dependent chaperoning
@en
P2093
Elisha D W Mackey
Henry A Lester
Rahul Srinivasan
Rigo Pantoja
P2860
P356
10.1085/JGP.201010532
P577
2011-01-01T00:00:00Z