Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity. - Wikidata - awgldk - TriplyDB

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.

http://www.wikidata.org/entity/Q34439684

about

ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies Transcriptional regulatory cascades in Runx2-dependent bone development Incoherent feed-forward regulatory loops control segregation of C-mechanoreceptors, nociceptors, and pruriceptors Abnormal behaviors and developmental disorder of hippocampus in zinc finger protein 521 (ZFP521) mutant mice Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling.Runx2 is required for early stages of endochondral bone formation but delays final stages of bone repair in Axin2-deficient mice.Direct transcriptional repression of Zfp423 by Zfp521 mediates a bone morphogenic protein-dependent osteoblast versus adipocyte lineage commitment switch Indian hedgehog signaling regulates transcription and expression of collagen type X via Runx2/Smads interactions.Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells.Genetic determinants of phosphate response in Drosophila.Foxp1/2/4 regulate endochondral ossification as a suppresser complex Hdac-mediated control of endochondral and intramembranous ossification Computational Modeling of a Transcriptional Switch Underlying B-Lymphocyte Lineage Commitment of Hematopoietic Multipotent Cells.Histone deacetylase 3 is required for maintenance of bone mass during aging Development of the endochondral skeleton Runx2 protein represses Axin2 expression in osteoblasts and is required for craniosynostosis in Axin2-deficient mice Transient Intermittent Hypoxia Exposure Disrupts Neonatal Bone Strength Pannexin 3 and connexin 43 modulate skeletal development through their distinct functions and expression patterns.Coordinated transcriptional regulation of bone homeostasis by Ebf1 and Zfp521 in both mesenchymal and hematopoietic lineages.PTH Signaling and Epigenetic Control of Bone Remodeling.A novel zinc finger protein 219-like (ZNF219L) is involved in the regulation of collagen type 2 alpha 1a (col2a1a) gene expression in zebrafish notochord Review of Signaling Pathways Governing MSC Osteogenic and Adipogenic Differentiation.Bone cell senescence: mechanisms and perspectives.Chromatin modifiers and histone modifications in bone formation, regeneration, and therapeutic intervention for bone-related disease.Consequences of chromsome18q deletions.Expression profiling and functional implications of a set of zinc finger proteins, ZNF423, ZNF470, ZNF521, and ZNF780B, in primary osteoarthritic articular chondrocytes.Expression of TLE3 by bone marrow stromal cells is regulated by canonical Wnt signaling.Inhibition of mechanical stress-induced NF-κB promotes bone formation.A zinc finger protein Zfp521 directs neural differentiation and beyond Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression.Histone deacetylases and their roles in mineralized tissue regeneration ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia.Histone deacetylase 3 suppresses Erk phosphorylation and matrix metalloproteinase (Mmp)-13 activity in chondrocytes.Primary Osteoporosis Is Not Reflected by Disease-Specific DNA Methylation or Accelerated Epigenetic Age in Blood.Zinc finger protein 521 overexpression increased transcript levels of Fndc5 in mouse embryonic stem cells.Connexin43 and Runx2 Interact to Affect Cortical Bone Geometry, Skeletal Development, and Osteoblast and Osteoclast Function.RUNX2 binds ZNF521 and HDAC3 BGLAP gene expression is stimulated by RUNX2; WWTR1 and RB1 and inhibited by AR; YAP1 and ZNF521 β1 integrins mediate the BMP2 dependent transcriptional control of osteoblast differentiation and osteogenesis.Zfp521 works its zinc fingers to the bone.

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P2860

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.

http://www.wikidata.org/entity/Q34439684

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.

@ast

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.

@en

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.

@nl

type

label

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.

@ast

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.

@en

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.

@nl

prefLabel

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.

@ast

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.

@en

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.

@nl

P1433

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P2860

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Journal of Cell Biology

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Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.

@en

P2093

Azeddine Atfi

http://www.w3.org/2001/XMLSchema#string

Daniel Toben

http://www.w3.org/2001/XMLSchema#string

Diego Correa

http://www.w3.org/2001/XMLSchema#string

Eric Hesse

http://www.w3.org/2001/XMLSchema#string

Georg Duda

http://www.w3.org/2001/XMLSchema#string

Hiroaki Saito

http://www.w3.org/2001/XMLSchema#string

Kei Yamana

http://www.w3.org/2001/XMLSchema#string

Lynn Neff

http://www.w3.org/2001/XMLSchema#string

Riku Kiviranta

http://www.w3.org/2001/XMLSchema#string

Roland Baron

http://www.w3.org/2001/XMLSchema#string

P2860

The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation

Histone deacetylase 7 associates with Runx2 and represses its activity during osteoblast maturation in a deacetylation-independent manner

Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

Doubly truncated FosB isoform (Delta2DeltaFosB) induces osteosclerosis in transgenic mice and modulates expression and phosphorylation of Smads in osteoblasts independent of intrinsic AP-1 activity

Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

Early hematopoietic zinc finger protein (EHZF), the human homolog to mouse Evi3, is highly expressed in primitive human hematopoietic cells

Mammalian Krüppel-like transcription factors: more than just a pretty finger

Mutations in the RUNX2 gene in patients with cleidocranial dysplasia

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1271-1283

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scholarly article

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10.1083/JCB.201009107

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P433

7

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191

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2010-12-20T00:00:00Z

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49697572

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21173110

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3010073

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