FXR controls the tumor suppressor NDRG2 and FXR agonists reduce liver tumor growth and metastasis in an orthotopic mouse xenograft model.
about
Novel bile acid therapeutics for the treatment of chronic liver diseasesBile acid receptors and nonalcoholic fatty liver diseaseEmerging role of N-myc downstream-regulated gene 2 (NDRG2) in cancerClinical application of transcriptional activators of bile salt transporters.Cancer-promoting effects of microbial dysbiosis.Microenvironmental Influences on Metastasis Suppressor Expression and Function during a Metastatic Cell's Journey.Farnesoid X receptor associates with β-catenin and inhibits its activity in hepatocellular carcinomaUpregulation of microRNA-122 by farnesoid X receptor suppresses the growth of hepatocellular carcinoma cells.FXR and liver carcinogenesisTumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expressionFXR induces SOCS3 and suppresses hepatocellular carcinoma.Bile Acid Receptors and Liver Cancer.Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer.Farnesoid X receptor directly regulates xenobiotic detoxification genes in the long-lived Little mice.Metastasis suppressors in breast cancers: mechanistic insights and clinical potentialPreclinical models of multiple myeloma: a critical appraisal.Bile acid receptors as targets for drug development.FXR agonists as therapeutic agents for non-alcoholic fatty liver disease.Farnesoid X receptor modulators (2011 - 2014): a patent review.Hepatocellular Carcinoma in Non-alcoholic Fatty Liver Disease: Epidemiology, Pathogenesis, and Prevention.Clinical and pathological significance of N-Myc downstream-regulated gene 2 (NDRG2) in diverse human cancers.The nuclear bile acid receptor FXR controls the liver derived tumor suppressor histidine-rich glycoprotein.Loss of NDRG2 in liver microenvironment inhibits cancer liver metastasis by regulating tumor associate macrophages polarization.Effect of obeticholic acid on liver regeneration following portal vein embolization in an experimental model.Farnesoid X Receptor Activation Enhances Transforming Growth Factor β-Induced Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma CellsFXR, intestinal FiXeR of hepatocellular carcinoma?Molecular Targets in Hepatocarcinogenesis and Implications for Therapy
P2860
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P2860
FXR controls the tumor suppressor NDRG2 and FXR agonists reduce liver tumor growth and metastasis in an orthotopic mouse xenograft model.
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
FXR controls the tumor suppres ...... hotopic mouse xenograft model.
@ast
FXR controls the tumor suppres ...... hotopic mouse xenograft model.
@en
FXR controls the tumor suppres ...... hotopic mouse xenograft model.
@nl
type
label
FXR controls the tumor suppres ...... hotopic mouse xenograft model.
@ast
FXR controls the tumor suppres ...... hotopic mouse xenograft model.
@en
FXR controls the tumor suppres ...... hotopic mouse xenograft model.
@nl
prefLabel
FXR controls the tumor suppres ...... hotopic mouse xenograft model.
@ast
FXR controls the tumor suppres ...... hotopic mouse xenograft model.
@en
FXR controls the tumor suppres ...... hotopic mouse xenograft model.
@nl
P2093
P2860
P1433
P1476
FXR controls the tumor suppres ...... hotopic mouse xenograft model.
@en
P2093
Andreas Schulz
Claus Kremoser
Julia Schüler
Olaf Kinzel
Thomas Schlüter
Ulrich Abel
Ulrich Deuschle
P2860
P304
P356
10.1371/JOURNAL.PONE.0043044
P407
P577
2012-10-09T00:00:00Z