Multiple modes of ryanodine receptor 2 inhibition by flecainide. - Wikidata - awgldk - TriplyDB

Multiple modes of ryanodine receptor 2 inhibition by flecainide.

Multiple modes of ryanodine receptor 2 inhibition by flecainide.

http://www.wikidata.org/entity/Q34441392

about

In silico prediction of drug therapy in catecholaminergic polymorphic ventricular tachycardia.Selectivity of pharmacological tools: implications for use in cell physiology. A review in the theme: Cell signaling: proteins, pathways and mechanisms.Multiple targets for flecainide action: implications for cardiac arrhythmogenesis.Effect of flecainide derivatives on sarcoplasmic reticulum calcium release suggests a lack of direct action on the cardiac ryanodine receptor.Molecular basis of hERG potassium channel blockade by the class Ic antiarrhythmic flecainide.Reply from Pei-Chi Yang, Jonathan D. Moreno, Mao-Tsuen Jeng, Xander H. T. Wehrens, Sergei Noskov and Colleen E. Clancy.EL20, A Potent Antiarrhythmic Compound, Selectively Inhibits Calmodulin Deficient Ryanodine Receptor Type 2.

P2860

Q36667578-EC06699D-B05F-4D26-A615-3DEBFD2A7BD1 Q38336214-B465791E-22A6-4B79-A768-DCCF50C315DC Q39215625-DE239781-1E78-4971-B329-CB1F29F24026 Q39727420-7B8E1DA0-53CD-4806-8BFE-0322220850BD Q43070404-03662A44-1FF1-4C80-BDD5-BE633CE045CD Q46137231-44F77A8D-46E8-42CF-9259-3518A1BA435E Q47297069-73D51894-1CA1-4749-BF57-730D9C0AD1C6

P2860

Multiple modes of ryanodine receptor 2 inhibition by flecainide.

http://www.wikidata.org/entity/Q34441392

description

2014 nî lūn-bûn

@nan

2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Multiple modes of ryanodine receptor 2 inhibition by flecainide.

@ast

Multiple modes of ryanodine receptor 2 inhibition by flecainide.

@en

Multiple modes of ryanodine receptor 2 inhibition by flecainide.

@nl

type

label

Multiple modes of ryanodine receptor 2 inhibition by flecainide.

@ast

Multiple modes of ryanodine receptor 2 inhibition by flecainide.

@en

Multiple modes of ryanodine receptor 2 inhibition by flecainide.

@nl

prefLabel

Multiple modes of ryanodine receptor 2 inhibition by flecainide.

@ast

Multiple modes of ryanodine receptor 2 inhibition by flecainide.

@en

Multiple modes of ryanodine receptor 2 inhibition by flecainide.

@nl

P1433

Q34441392-5699522B-E7C9-45D6-95BA-C05E22F5FA72

P1476

Q34441392-6B6298CC-5FE8-4728-ABBC-0C3E074F2829

P2093

Q34441392-28B117E4-0A13-48E8-8DDE-911C09FD448C

Q34441392-84072950-7947-4836-86C3-20561F86162B

Q34441392-BB4B718F-4D6B-4C32-B412-C16F7005594A

Q34441392-DD5A1A22-7CBB-4328-A326-E3F760CB9DB9

P2860

Q34441392-04DAC142-B88F-4407-AA84-0B629D749626

Q34441392-05505287-68EB-4DEB-9AE6-1215A3212FE3

Q34441392-0B186025-A47C-41A5-87F3-912887F6E7E2

Q34441392-134BDE6F-4013-414F-8105-65007C975FEC

Q34441392-17FD58B4-75B3-4D7C-A2A2-59649057337B

Q34441392-17FF610F-669D-4047-BE69-841F19906E29

Q34441392-23EA7E7A-4887-4252-95E0-3BF210221903

Q34441392-346415C1-051C-4247-AD9E-9306C44E49CB

Q34441392-3A22A1C7-49EB-415D-B51E-6A3CE82CD34D

Q34441392-46F4C96C-2259-4BED-A1D2-9A21CE19DC4D

P304

Q34441392-D200B704-16BE-4637-A1DD-A44725E9AD64

P31

Q34441392-39DCCFE7-4EA0-4A00-96F0-3779BBFF6CB5

P356

Q34441392-9B709F72-1B85-4368-B08C-DFC6F4529774

P433

Q34441392-1C6B1AD2-D498-4BCF-9305-0F35935E1A34

P478

Q34441392-4E1C1745-2E67-40B2-93B0-CA987945660C

P50

Q34441392-9649103F-A813-428D-94D1-4462510CE28F

P577

Q34441392-4BBA67FD-3F2C-411B-82CE-4554175F762A

P5875

Q34441392-3D62DF25-668E-4AEA-ABFF-C6C99D230834

P698

Q34441392-E25D0757-FDF9-4985-8820-105871595F7A

P932

Q34441392-1652F7EE-B69E-49AB-B091-622922413A33

P356

P1433

Molecular Pharmacology

P1476

Multiple modes of ryanodine receptor 2 inhibition by flecainide

@en

P2093

D F van Helden

http://www.w3.org/2001/XMLSchema#string

D Mehra

http://www.w3.org/2001/XMLSchema#string

D R Laver

http://www.w3.org/2001/XMLSchema#string

M S Imtiaz

http://www.w3.org/2001/XMLSchema#string

P2860

Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death

Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes

Sodium channel molecular conformations and antiarrhythmic drug affinity

Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans

Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia

Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels

Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia

Subconductance activity induced by quinidine and quinidinium in purified cardiac sarcoplasmic reticulum calcium release channels.

Data transformations for improved display and fitting of single-channel dwell time histograms

Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass.

P304

696-706

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1124/MOL.114.094623

http://www.w3.org/2001/XMLSchema#string

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

86

http://www.w3.org/2001/XMLSchema#string

P50

Bjorn C. Knollmann

P577

2014-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

266570298

http://www.w3.org/2001/XMLSchema#string

P698

25274603

http://www.w3.org/2001/XMLSchema#string

P932

4244595

http://www.w3.org/2001/XMLSchema#string