Iron metabolism regulates p53 signaling through direct heme-p53 interaction and modulation of p53 localization, stability, and function.
about
Heme dynamics and trafficking factors revealed by genetically encoded fluorescent heme sensors.Artemisinin and Its Derivatives as a Repurposing Anticancer Agent: What Else Do We Need to Do?A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of FerrochelataseSurvival rates of homozygotic Tp53 knockout rats as a tool for preclinical assessment of cancer prevention and treatmentNuclear cytoplasmic trafficking of proteins is a major response of human fibroblasts to oxidative stressIron homeostasis and tumorigenesis: molecular mechanisms and therapeutic opportunitiesCombined bortezomib-based chemotherapy and p53 gene therapy using hollow mesoporous silica nanospheres for p53 mutant non-small cell lung cancer treatment.The effects of a novel aliphatic-chain hydroxamate derivative WMJ-S-001 in HCT116 colorectal cancer cell death.Targeting cancer by binding iron: Dissecting cellular signaling pathwaysHaem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistanceNovel p53-dependent anticancer strategy by targeting iron signaling and BNIP3L-induced mitophagy.The heme-p53 interaction: Linking iron metabolism to p53 signaling and tumorigenesis.Regulation of intracellular heme trafficking revealed by subcellular reportersRegulation of heme biosynthesis and transport in metazoa.Heme Mobilization in Animals: A Metallolipid's Journey.Heme Gazing: Illuminating Eukaryotic Heme Trafficking, Dynamics, and Signaling with Fluorescent Heme Sensors.Natural product pectolinarigenin inhibits osteosarcoma growth and metastasis via SHP-1-mediated STAT3 signaling inhibition.miR-20a regulates expression of the iron exporter ferroportin in lung cancer.Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal TumorigenesisA Tough Nut to Crack: Intracellular Detection and Quantification of Heme in Malaria Parasites by a Genetically Encoded Protein Sensor.Docking of CDK1 with antibiotic drugs revealed novel therapeutic value in breast ductal cancer in situ.Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2.The relationship between iron bone marrow stores and response to treatment in pediatric acute lymphoblastic leukemia.Overexpression of AGT promotes bronchopulmonary dysplasis via the JAK/STAT signal pathway.Metal transporter Slc39a10 regulates susceptibility to inflammatory stimuli by controlling macrophage survival.F-box proteins in epigenetic regulation of cancer.The Tumor Suppressor, P53, Decreases the Metal Transporter, ZIP14.Erythroleukemia-historical perspectives and recent advances in diagnosis and management.The heme-regulatory motif of nuclear receptor Rev-erbβ is a key mediator of heme and redox signaling in circadian rhythm maintenance and metabolism.Progesterone Receptor Membrane Component 1 suppresses the p53 and Wnt/β-catenin pathways to promote human pluripotent stem cell self-renewal.High-Dose Deferoxamine Treatment Disrupts Intracellular Iron Homeostasis, Reduces Growth, and Induces Apoptosis in Metastatic and Nonmetastatic Breast Cancer Cell Lines.Piperazinyl fragment improves anticancer activity of Triapine.Isomangiferin, a Novel Potent Vascular Endothelial Growth Factor Receptor 2 Kinase Inhibitor, Suppresses Breast Cancer Growth, Metastasis and Angiogenesis.Heme and hemoglobin suppress amyloid β-mediated inflammatory activation of mouse astrocytes.Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress.Till Death Do Us Part: The Marriage of Autophagy and Apoptosis.Experimental Methods for Studying Cellular Heme Signaling.Roles of p53 in extrinsic factor-induced liver carcinogenesis
P2860
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P2860
Iron metabolism regulates p53 signaling through direct heme-p53 interaction and modulation of p53 localization, stability, and function.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Iron metabolism regulates p53 ...... tion, stability, and function.
@ast
Iron metabolism regulates p53 ...... tion, stability, and function.
@en
Iron metabolism regulates p53 ...... tion, stability, and function.
@nl
type
label
Iron metabolism regulates p53 ...... tion, stability, and function.
@ast
Iron metabolism regulates p53 ...... tion, stability, and function.
@en
Iron metabolism regulates p53 ...... tion, stability, and function.
@nl
prefLabel
Iron metabolism regulates p53 ...... tion, stability, and function.
@ast
Iron metabolism regulates p53 ...... tion, stability, and function.
@en
Iron metabolism regulates p53 ...... tion, stability, and function.
@nl
P2093
P2860
P1433
P1476
Iron metabolism regulates p53 ...... tion, stability, and function.
@en
P2093
Kangchen Ruan
Lijian Hui
Ronggui Hu
P2860
P304
P356
10.1016/J.CELREP.2014.02.042
P577
2014-03-27T00:00:00Z