Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor. - Wikidata - awgldk - TriplyDB

Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor.

Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor.

http://www.wikidata.org/entity/Q34449990

about

Transthyretin and the brain re-visited: is neuronal synthesis of transthyretin protective in Alzheimer's disease?beta-Amyloid degradation and Alzheimer's disease A modern understanding of the traditional and nontraditional biological functions of angiotensin-converting enzyme Abeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzyme Cerebrovascular disease in ageing and Alzheimer's disease β-Amyloid: the key peptide in the pathogenesis of Alzheimer's disease Endothelin-converting enzymes and related metalloproteases in Alzheimer's disease ACE overexpression in myelomonocytic cells: effect on a mouse model of Alzheimer's disease The genetics of Alzheimer disease Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer's-like cognitive decline Alterations in synaptic plasticity coincide with deficits in spatial working memory in presymptomatic 3xTg-AD mice.Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics.Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements Identification of beta-secretase (BACE1) substrates using quantitative proteomics.Gestational protein restriction increases angiotensin II production in rat lung.An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3.The association of angiotensin-converting enzyme with biomarkers for Alzheimer's disease Expression of ACE and ACE2 in patients with hypertensive nephrosclerosis.ACE polymorphism and use of ACE inhibitors: effects on memory performance.ACE variants and association with brain Aβ levels in Alzheimer's disease Unintended effects of cardiovascular drugs on the pathogenesis of Alzheimer's disease Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation Association of polymorphisms in the Angiotensin-converting enzyme gene with Alzheimer disease in an Israeli Arab community Angiotensin receptor blockers and risk of dementia: cohort study in UK Clinical Practice Research Datalink.The peptide network regulated by angiotensin converting enzyme (ACE) in hematopoiesis Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid beta-peptides in human cerebrospinal fluid The carboxypeptidase ACE shapes the MHC class I peptide repertoire Antihypertensive drugs, prevention of cognitive decline and dementia: a systematic review of observational studies, randomized controlled trials and meta-analyses, with discussion of potential mechanisms.Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra.Telmisartan Modulates Glial Activation: In Vitro and In Vivo Studies Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease.17β-estradiol and progesterone regulate expression of β-amyloid clearance factors in primary neuron cultures and female rat brain The involvement of lipid rafts in Alzheimer's disease.Roles of Brain Angiotensin II in Cognitive Function and Dementia.Vitamin D interacts with Esr1 and Igf1 to regulate molecular pathways relevant to Alzheimer's disease Disease modifying therapy for AD?Novel modulators of amyloid-beta precursor protein processing.The Role of the Renin-Angiotensin System in Amyloid Metabolism of Alzheimer's Disease A Low-Protein Diet Enhances Angiotensin II Production in the Lung of Pregnant Rats but not Nonpregnant Rats.

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P2860

Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor.

http://www.wikidata.org/entity/Q34449990

description

2005 nî lūn-bûn

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2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Amyloid beta-protein is degrad ...... elevated by an ACE inhibitor.

@ast

Amyloid beta-protein is degrad ...... elevated by an ACE inhibitor.

@en

Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme

@nl

type

label

Amyloid beta-protein is degrad ...... elevated by an ACE inhibitor.

@ast

Amyloid beta-protein is degrad ...... elevated by an ACE inhibitor.

@en

Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme

@nl

prefLabel

Amyloid beta-protein is degrad ...... elevated by an ACE inhibitor.

@ast

Amyloid beta-protein is degrad ...... elevated by an ACE inhibitor.

@en

Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme

@nl

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Journal of Biological Chemistry

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Amyloid beta-protein is degrad ...... elevated by an ACE inhibitor.

@en

P2093

Dennis J Selkoe

http://www.w3.org/2001/XMLSchema#string

Matthew L Hemming

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P2860

Angiotensin-converting enzyme is involved in outside-in signaling in endothelial cells

Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria

The two homologous domains of human angiotensin I-converting enzyme are both catalytically active

The two homologous domains of human angiotensin I-converting enzyme interact differently with competitive inhibitors

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

Large meta-analysis establishes the ACE insertion-deletion polymorphism as a marker of Alzheimer's disease

Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme

Shedding of somatic angiotensin-converting enzyme (ACE) is inefficient compared with testis ACE despite cleavage at identical stalk sites

Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta ); retards A beta aggregation, deposition, fibril formation; and inhibits cytotoxicity.

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37644-37650

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scholarly article

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10.1074/JBC.M508460200

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45

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280

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2005-09-09T00:00:00Z

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16154999

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2409196

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