DCM-related tropomyosin mutants E40K/E54K over-inhibit the actomyosin interaction and lead to a decrease in the number of cycling cross-bridges.
about
Structural and protein interaction effects of hypertrophic and dilated cardiomyopathic mutations in alpha-tropomyosin.Analysis of the molecular pathogenesis of cardiomyopathy-causing cTnT mutants I79N, ΔE96, and ΔK210.Diversity and similarity of motor function and cross-bridge kinetics in papillary muscles of transgenic mice carrying myosin regulatory light chain mutations D166V and R58QA study of tropomyosin's role in cardiac function and disease using thin-filament reconstituted myocardium.Alpha-tropomyosin mutations in inherited cardiomyopathies.Using baculovirus/insect cell expressed recombinant actin to study the molecular pathogenesis of HCM caused by actin mutation A331PNoncanonical roles for Tropomyosin during myogenesis.HCM and DCM cardiomyopathy-linked α-tropomyosin mutations influence off-state stability and crossbridge interaction on thin filaments.
P2860
Q34608346-343895CD-B16C-4BF8-B839-4D7E063FC4F9Q36824519-844A1FBC-15CA-43E8-ACA8-19CEF1252984Q37257335-38CF49DC-B0B3-431C-8AA8-D2D64DDED216Q38108764-0D6B7BEF-DC8F-4188-9798-10A06F06E64DQ38134256-440FAC5D-E26F-4B03-9A99-247D9162FB8DQ38998926-003466FB-489A-48D9-A50C-A345C5456A4BQ47070003-7CB31AD8-FE64-4AF0-8CB9-EB0D65C1A540Q53416334-E83F164C-35CC-4986-ADBF-64C1201AF0D5
P2860
DCM-related tropomyosin mutants E40K/E54K over-inhibit the actomyosin interaction and lead to a decrease in the number of cycling cross-bridges.
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
DCM-related tropomyosin mutant ...... mber of cycling cross-bridges.
@ast
DCM-related tropomyosin mutant ...... mber of cycling cross-bridges.
@en
DCM-related tropomyosin mutant ...... mber of cycling cross-bridges.
@nl
type
label
DCM-related tropomyosin mutant ...... mber of cycling cross-bridges.
@ast
DCM-related tropomyosin mutant ...... mber of cycling cross-bridges.
@en
DCM-related tropomyosin mutant ...... mber of cycling cross-bridges.
@nl
prefLabel
DCM-related tropomyosin mutant ...... mber of cycling cross-bridges.
@ast
DCM-related tropomyosin mutant ...... mber of cycling cross-bridges.
@en
DCM-related tropomyosin mutant ...... mber of cycling cross-bridges.
@nl
P2860
P1433
P1476
DCM-related tropomyosin mutant ...... umber of cycling cross-bridges
@en
P2093
Heather L Groth
P2860
P304
P356
10.1371/JOURNAL.PONE.0047471
P407
P577
2012-10-15T00:00:00Z