Highly sensitive apurinic/apyrimidinic site assay can detect spontaneous and chemically induced depurination under physiological conditions.
about
High-efficiency bypass of DNA damage by human DNA polymerase QA mechanism for the exclusion of low-fidelity human Y-family DNA polymerases from base excision repairA DNA enzyme with N-glycosylase activityLinking uracil base excision repair and 5-fluorouracil toxicity in yeastStructure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4: GUANINE N2,N2-DIMETHYL SUBSTITUTION PRODUCES INACTIVE AND MISCODING POLYMERASE COMPLEXESDNA Polymerase Substrate Specificity: SIDE CHAIN MODULATION OF THE"A-RULE"Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNAA screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions.Epigenetic reduction of DNA repair in progression to gastrointestinal cancerCockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediatesIdentification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1NSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase β and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer CellsThe efficiency of the translesion synthesis across abasic sites by mitochondrial DNA polymerase is low in mitochondria of 3T3 cellsOn the formation and properties of interstrand DNA-DNA cross-links forged by reaction of an abasic site with the opposing guanine residue of 5'-CAp sequences in duplex DNA.Sensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesionsA method for detecting abasic sites in living cells: age-dependent changes in base excision repairThe endogenous exposome.Inverse radiation dose-rate effects on somatic and germ-line mutations and DNA damage ratesMutations associated with base excision repair deficiency and methylation-induced genotoxic stressEndogenous versus exogenous DNA adducts: their role in carcinogenesis, epidemiology, and risk assessment.Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNAStructural insights by molecular dynamics simulations into specificity of the major human AP endonuclease toward the benzene-derived DNA adduct, pBQ-C.Identification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitorsAccumulation of true single strand breaks and AP sites in base excision repair deficient cellsUracil-DNA glycosylase expression determines human lung cancer cell sensitivity to pemetrexed.Aging genomes: a necessary evil in the logic of life.Redox regulation of apurinic/apyrimidinic endonuclease 1 activity in Long-Evans Cinnamon rats during spontaneous hepatitisCharacterization of the aldehyde reactive probe reaction with AP-sites in DNA: influence of AP-lyase on adduct stabilityTemporal and functional analysis of DNA replicated in early S phase.Micromolar concentrations of hydrogen peroxide induce oxidative DNA lesions more efficiently than millimolar concentrations in mammalian cells.Detecting DNA depurination with solid-state nanopores.Downregulation of hPMC2 imparts chemotherapeutic sensitivity to alkylating agents in breast cancer cellsDNA Repair and Cancer Therapy: Targeting APE1/Ref-1 Using Dietary AgentsQuantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time.DNA polymerase POLQ and cellular defense against DNA damage.Saccharomyces cerevisiae Apn1 mutation affecting stable protein expression mimics catalytic activity impairment: implications for assessing DNA repair capacity in humansSources of contradictions in the evaluation of population genetic consequences after the chernobyl disaster.Adenomatous polyposis coli-mediated accumulation of abasic DNA lesions lead to cigarette smoke condensate-induced neoplastic transformation of normal breast epithelial cells.Synthesis and characterization of DNA minor groove binding alkylating agentsA unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification.
P2860
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P2860
Highly sensitive apurinic/apyrimidinic site assay can detect spontaneous and chemically induced depurination under physiological conditions.
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Highly sensitive apurinic/apyr ...... nder physiological conditions.
@ast
Highly sensitive apurinic/apyr ...... nder physiological conditions.
@en
Highly sensitive apurinic/apyr ...... nder physiological conditions.
@nl
type
label
Highly sensitive apurinic/apyr ...... nder physiological conditions.
@ast
Highly sensitive apurinic/apyr ...... nder physiological conditions.
@en
Highly sensitive apurinic/apyr ...... nder physiological conditions.
@nl
prefLabel
Highly sensitive apurinic/apyr ...... nder physiological conditions.
@ast
Highly sensitive apurinic/apyr ...... nder physiological conditions.
@en
Highly sensitive apurinic/apyr ...... nder physiological conditions.
@nl
P2093
P1433
P1476
Highly sensitive apurinic/apyr ...... nder physiological conditions.
@en
P2093
P304
P407
P577
1998-01-01T00:00:00Z