Identification of substrates and regulators of the mitogen-activated protein kinase ERK5 using chimeric protein kinases.
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miR-143 interferes with ERK5 signaling, and abrogates prostate cancer progression in miceERK5 is targeted to myocyte enhancer factor 2A (MEF2A) through a MAPK docking motifCharacterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamilyErk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2MEK5, a new target of the atypical protein kinase C isoforms in mitogenic signalingTyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer.X-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific InhibitorERK5 Mediated Signalling in Diabetic RetinopathyERK5 and ERK2 cooperate to regulate NF-kappaB and cell transformationMEKK1 binds raf-1 and the ERK2 cascade componentsContribution of the ERK5/MEK5 pathway to Ras/Raf signaling and growth controlIdentification of novel point mutations in ERK2 that selectively disrupt binding to MEK1MEK5 and ERK5 are localized in the nuclei of resting as well as stimulated cells, while MEKK2 translocates from the cytosol to the nucleus upon stimulationTargeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathwayRole of MAP kinases in the 1,25-dihydroxyvitamin D3-induced transactivation of the rat cytochrome P450C24 (CYP24) promoter. Specific functions for ERK1/ERK2 and ERK5Extracellular signal-regulated kinase 7 (ERK7), a novel ERK with a C-terminal domain that regulates its activity, its cellular localization, and cell growth.WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain IIErk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell IdentityCanonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complexDe-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis.The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42ERK5 MAP kinase regulates neurogenin1 during cortical neurogenesis.Growth and stress response mechanisms underlying post-feeding regenerative organ growth in the Burmese python.Calcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction.Granulocyte colony-stimulating factor induces ERK5 activation, which is differentially regulated by protein-tyrosine kinases and protein kinase C. Regulation of cell proliferation and survival.MEK and the inhibitors: from bench to bedside.Different domains of the mitogen-activated protein kinases ERK3 and ERK2 direct subcellular localization and upstream specificity in vivo.The atypical protein kinase Cs. Functional specificity mediated by specific protein adaptersForced expression of miR-143 represses ERK5/c-Myc and p68/p72 signaling in concert with miR-145 in gut tumors of Apc(Min) mice.Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.Ras-MAP kinase signaling pathways and control of cell proliferation: relevance to cancer therapy.The role of specific mitogen-activated protein kinase signaling cascades in the regulation of steroidogenesisERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons.Mitogen/extracellular signal-regulated kinase kinase-5 promoter region polymorphisms affect the risk of sporadic colorectal cancer in a southern Chinese populationMEK5 overexpression is associated with the occurrence and development of colorectal cancerA novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis.MAPK signalling: ERK5 versus ERK1/2.Mitogenic growth signalling, DNA replication licensing, and survival are linked in prostate cancerERK5 promotes Src-induced podosome formation by limiting Rho activation.c-Myc target gene specificity is determined by a post-DNAbinding mechanism
P2860
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P2860
Identification of substrates and regulators of the mitogen-activated protein kinase ERK5 using chimeric protein kinases.
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Identification of substrates a ...... sing chimeric protein kinases.
@ast
Identification of substrates a ...... sing chimeric protein kinases.
@en
Identification of substrates a ...... sing chimeric protein kinases.
@nl
type
label
Identification of substrates a ...... sing chimeric protein kinases.
@ast
Identification of substrates a ...... sing chimeric protein kinases.
@en
Identification of substrates a ...... sing chimeric protein kinases.
@nl
prefLabel
Identification of substrates a ...... sing chimeric protein kinases.
@ast
Identification of substrates a ...... sing chimeric protein kinases.
@en
Identification of substrates a ...... sing chimeric protein kinases.
@nl
P2093
P2860
P356
P1476
Identification of substrates a ...... using chimeric protein kinases
@en
P2093
P2860
P304
P356
10.1074/JBC.273.7.3854
P407
P577
1998-02-01T00:00:00Z