Targeted elimination of prostate cancer by genetically directed human T lymphocytes.
about
PSMA-specific CAR-engineered T cells eradicate disseminated prostate cancer in preclinical modelsImmunotherapy in metastatic prostate cancerRecovery and Biodistribution of Ex Vivo Expanded Human Erythroblasts Injected into NOD/SCID/IL2Rγ micePD-1- and CTLA-4-based inhibitory chimeric antigen receptors (iCARs) divert off-target immunotherapy responsesPTEN knockout prostate cancer as a model for experimental immunotherapyRetrovirally transduced murine T lymphocytes expressing FasL mediate effective killing of prostate cancer cellsEmerging immunotherapeutics in adenocarcinomas: A focus on CAR-T cellsIL-7 and IL-21 are superior to IL-2 and IL-15 in promoting human T cell-mediated rejection of systemic lymphoma in immunodeficient mice.Targeting of mesenchymal stem cells to ovarian tumors via an artificial receptor.In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers.Prostate-specific membrane antigen retargeted measles virotherapy for the treatment of prostate cancer.The promise and potential pitfalls of chimeric antigen receptors.Genetically retargeting CD8+ lymphocyte subsets for cancer immunotherapy.Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity.Tumor-Targeted Human T Cells Expressing CD28-Based Chimeric Antigen Receptors Circumvent CTLA-4 Inhibition.Chimeric antigen receptor-engineered T cells for the treatment of metastatic prostate cancer.A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer.T cells engineered with a T cell receptor against the prostate antigen TARP specifically kill HLA-A2+ prostate and breast cancer cellsCell vehicle targeting strategies.Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition.Genetically engineered T cells to target EGFRvIII expressing glioblastoma.Monitoring the efficacy of adoptively transferred prostate cancer-targeted human T lymphocytes with PET and bioluminescence imaging.Enhancing adoptive immunotherapy of cancer.Chimeric antigen receptor T cells: a novel therapy for solid tumors.Chimeric antigen receptor-engineered T cells for immunotherapy of cancer.Targeting the prostate-specific membrane antigen for prostate cancer therapy.Chimeric antigen receptors in cancer immuno-gene therapy: current status and future directions.Reporter gene imaging of immune responses to cancer: progress and challenges.miR-34a inhibits cell proliferation in prostate cancer by downregulation of SIRT1 expressionEnhancement of PSMA-Directed CAR Adoptive Immunotherapy by PD-1/PD-L1 Blockade.Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferaseChimeric antigen receptors combining 4-1BB and CD28 signaling domains augment PI3kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication.A new pyrimidine-specific reporter gene: a mutated human deoxycytidine kinase suitable for PET during treatment with acycloguanosine-based cytotoxic drugs.Genetically engineered T cells expressing a HER2-specific chimeric receptor mediate antigen-specific tumor regression.T cell-encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection.Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection.Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells.Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells.Nature of tumor control by permanently and transiently modified GD2 chimeric antigen receptor T cells in xenograft models of neuroblastoma.Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo.
P2860
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P2860
Targeted elimination of prostate cancer by genetically directed human T lymphocytes.
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Targeted elimination of prostate cancer by genetically directed human T lymphocytes.
@ast
Targeted elimination of prostate cancer by genetically directed human T lymphocytes.
@en
Targeted elimination of prostate cancer by genetically directed human T lymphocytes.
@nl
type
label
Targeted elimination of prostate cancer by genetically directed human T lymphocytes.
@ast
Targeted elimination of prostate cancer by genetically directed human T lymphocytes.
@en
Targeted elimination of prostate cancer by genetically directed human T lymphocytes.
@nl
prefLabel
Targeted elimination of prostate cancer by genetically directed human T lymphocytes.
@ast
Targeted elimination of prostate cancer by genetically directed human T lymphocytes.
@en
Targeted elimination of prostate cancer by genetically directed human T lymphocytes.
@nl
P2093
P1433
P1476
Targeted elimination of prostate cancer by genetically directed human T lymphocytes.
@en
P2093
Clay Lyddane
Elmer Santos
Gertrude Gunset
Ian M Buchanan
Isabelle Rivière
Jason A Koutcher
Jolanta Stefanski
Matthias Stephan
Michael C Gong
Michel Sadelain
P304
P356
10.1158/0008-5472.CAN-05-0436
P407
P577
2005-10-01T00:00:00Z