Putting its fingers on stressful situations: the heavy metal-regulatory transcription factor MTF-1.
about
Induction of metallothionein I by arsenic via metal-activated transcription factor 1. Critical role of c-terminal cysteine residues in arsenic sensingInduction of metallothionein l by phenolic antioxidants requires metal-activated transcription factor 1 (MTF-1) and zincTwo major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathioneA cadmium-transporting P1B-type ATPase in yeast Saccharomyces cerevisiae.Heat and heavy metal stress synergize to mediate transcriptional hyperactivation by metal-responsive transcription factor MTF-1Metal-responsive transcription factor (MTF-1) and heavy metal stress response in Drosophila and mammalian cells: a functional comparisonHypoxia acts through multiple signaling pathways to induce metallothionein transactivation by the metal-responsive transcription factor-1 (MTF-1)The metal-responsive transcription factor-1 protein is elevated in human tumorsZinc is a novel intracellular second messengerTexaphyrins and water-soluble zinc(II) ionophores: development, mechanism of anticancer activity, and synergistic effectsDumpy-30 family members as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila.Age-related cellular copper dynamics in the fungal ageing model Podospora anserina and in ageing human fibroblasts.Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes.The parkin mutant phenotype in the fly is largely rescued by metal-responsive transcription factor (MTF-1)Chromatin insulation by a transcriptional activator.Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis.The role of small ubiquitin-like modifier-interacting motif in the assembly and regulation of metal-responsive transcription factor 1.Metal-responsive transcription factors that regulate iron, zinc, and copper homeostasis in eukaryotic cells.Small-molecule proteostasis regulators for protein conformational diseases.Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical ApplicationThe Znt4 mutation inlethal milk mice affects intestinal zinc homeostasis through the expression of other Zn transportersRadiation carcinogenesis in mouse thymic lymphomas.The genetics of essential metal homeostasis during developmentCopper sensing function of Drosophila metal-responsive transcription factor-1 is mediated by a tetranuclear Cu(I) cluster.Identification of mutations in Caenorhabditis elegans that cause resistance to high levels of dietary zinc and analysis using a genomewide map of single nucleotide polymorphisms scored by pyrosequencing.Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteriesShort-lived mammals (shrew, mouse) have a less robust metal-responsive transcription factor than humans and bats.Activity of metal-responsive transcription factor 1 by toxic heavy metals and H2O2 in vitro is modulated by metallothionein.Protection against zinc toxicity by metallothionein and zinc transporter 1Natural and laboratory mutations in kuzbanian are associated with zinc stress phenotypes in Drosophila melanogaster.Texaphyrins: tumor localizing redox active expanded porphyrinsZinc homeostasis and signaling in health and diseases: Zinc signaling.A common response to common danger? Comparison of animal and plant signaling pathways involved in cadmium sensing.Predisposition to mouse thymic lymphomas in response to ionizing radiation depends on variant alleles encoding metal-responsive transcription factor-1 (Mtf-1).Leptin deficiency enhances sensitivity of rats to alcoholic steatohepatitis through suppression of metallothionein.The zinc-sensing mechanism of mouse MTF-1 involves linker peptides between the zinc fingers.Drosophila melanogaster Models of Metal-Related Human Diseases and Metal Toxicity.Zinc-induced formation of a coactivator complex containing the zinc-sensing transcription factor MTF-1, p300/CBP, and Sp1Dynamics of the metal-dependent transcription factor complex in vivo at the mouse metallothionein-I promoter.Gene- and cell-type-specific effects of signal transduction cascades on metal-regulated gene transcription appear to be independent of changes in the phosphorylation of metal-response-element-binding transcription factor-1.
P2860
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P2860
Putting its fingers on stressful situations: the heavy metal-regulatory transcription factor MTF-1.
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Putting its fingers on stressf ...... ry transcription factor MTF-1.
@ast
Putting its fingers on stressf ...... ry transcription factor MTF-1.
@en
Putting its fingers on stressf ...... ry transcription factor MTF-1.
@nl
type
label
Putting its fingers on stressf ...... ry transcription factor MTF-1.
@ast
Putting its fingers on stressf ...... ry transcription factor MTF-1.
@en
Putting its fingers on stressf ...... ry transcription factor MTF-1.
@nl
prefLabel
Putting its fingers on stressf ...... ry transcription factor MTF-1.
@ast
Putting its fingers on stressf ...... ry transcription factor MTF-1.
@en
Putting its fingers on stressf ...... ry transcription factor MTF-1.
@nl
P2860
P356
P1433
P1476
Putting its fingers on stressf ...... ry transcription factor MTF-1.
@en
P2093
Lichtlen P
Schaffner W
P2860
P304
P356
10.1002/BIES.1146
P407
P577
2001-11-01T00:00:00Z