Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3. - Wikidata - awgldk - TriplyDB

Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3.

Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3.

http://www.wikidata.org/entity/Q34467047

about

PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway CCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization Adaptor protein cerebral cavernous malformation 3 (CCM3) mediates phosphorylation of the cytoskeletal proteins ezrin/radixin/moesin by mammalian Ste20-4 to protect cells from oxidative stress A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity Cerebral cavernous malformation is a vascular disease associated with activated RhoA signaling Molecular Recognition of Leucine-Aspartate Repeat (LD) Motifs by the Focal Adhesion Targeting Homology Domain of Cerebral Cavernous Malformation 3 (CCM3)Structural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD-FERM interface Structural basis for the disruption of the cerebral cavernous malformations 2 (CCM2) interaction with Krev interaction trapped 1 (KRIT1) by disease-associated mutations Phosphorylation sites in the cerebral cavernous malformations complex Advanced magnetic resonance imaging of cerebral cavernous malformations: part I. High-field imaging of excised human lesions CCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations Defining the functional domain of programmed cell death 10 through its interactions with phosphatidylinositol-3,4,5-trisphosphate.Role of cytoskeletal proteins in cerebral cavernous malformation signaling pathways: a proteomic analysis.Systems biology and proteomic analysis of cerebral cavernous malformation Protein phosphatase 2a (PP2A) binds within the oligomerization domain of striatin and regulates the phosphorylation and activation of the mammalian Ste20-Like kinase Mst3.Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development PDCD10 gene mutations in multiple cerebral cavernous malformations PDCD10/CCM3 acts downstream of {gamma}-protocadherins to regulate neuronal survival.Differential expression of MST4, STK25 and PDCD10 between benign prostatic hyperplasia and prostate cancer.Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation.Genetics of cerebral cavernous malformations: current status and future prospects Downregulation of programmed cell death 10 is associated with tumor cell proliferation, hyperangiogenesis and peritumoral edema in human glioblastoma.CCM3/SERPINI1 bidirectional promoter variants in patients with cerebral cavernous malformations: a molecular and functional study CCM3 Mutations Are Associated with Early-Onset Cerebral Hemorrhage and Multiple Meningiomas.Recent insights into cerebral cavernous malformations: the molecular genetics of CCM.Signaling pathways and the cerebral cavernous malformations proteins: lessons from structural biology.Advances in the biology of cerebral cavernous malformations.Genetic and cellular basis of cerebral cavernous malformations: implications for clinical management.CCM1 and the second life of proteins in adhesion complexes.Focal defects in single-celled tubes mutant for Cerebral cavernous malformation 3, GCKIII, or NSF2.Structure-function analysis of core STRIPAK Proteins: a signaling complex implicated in Golgi polarization.Apoptotic functions of PDCD10/CCM3, the gene mutated in cerebral cavernous malformation 3.Familial cerebral cavernomas due to a KRIT1 mutation presenting with epilepsy.CCM-3/STRIPAK promotes seamless tube extension through endocytic recycling.

P2860

Q24300270-136F3939-A629-49A7-AD45-3D7BFCA1962E Q24301965-902A8A64-7444-4CD6-8611-22F0C8F9BFEE Q24303978-5E7B422A-5862-47B1-8F47-E45AB7C486FF Q24311685-8268B6AB-FC39-4FC5-9631-7CFCFE1E9DFC Q24314384-AEA6C32C-7C0B-4550-97D3-61C7E14C6702 Q26849566-DE2F244E-AD45-41A8-A232-A80AEE3FB379 Q27668126-9A366F82-5541-45C7-8A40-5416944DD66F Q28607249-36065E8E-1A1C-493F-B6F0-108A6BA6E24B Q28650470-90F5F2AB-56B9-4F3E-97C2-1549FC4BD7B2 Q30423675-2DA3E499-406F-44A5-BE6F-68D7C55A8E25 Q30438393-E2A4E3F3-BC7D-4DEB-BBCF-516D1E7B538B Q30495754-7316CEC3-2C4F-448E-BD55-9692A7205AEF Q33644309-AC09705A-68C4-4294-B380-3F42975D45C9 Q33707224-42FA1910-2394-4896-86D3-9B78E970C1B4 Q33792147-2FB9B294-332F-4401-BFC6-F68772EC812B Q34045261-B79E9E56-72A9-40B6-A3F1-131A8A2EA01A Q34108757-C0249861-35AF-45AC-987E-0C03206629DD Q34420456-7F04E5B0-2FD7-4AD5-8FDD-C301E9007308 Q34438883-8B638A23-2B72-4C57-8615-C1897E206D2E Q34733416-50F2F649-8819-4E89-8CC6-A2F92D21BAD2 Q35167117-9077C84A-C577-46CC-9FD3-C0F5C9B108D0 Q35706117-252AA898-EE53-4665-B616-9253AFF3ED8F Q35816668-CBBC82C4-BB9B-482A-84AB-D9DD7C5D56AB Q36163127-79FCA868-E211-449E-88B7-7D9138E0BE0E Q36883373-66C19A46-DE81-4A3D-B7B5-07177C198CCD Q37680004-20C326FE-0C37-4D72-BD8F-C12DD8A4DD0B Q37722299-197B84C1-01CD-482A-B313-FA3C0AEC44FB Q37803129-3138727B-6CA3-437A-B599-3620187C5C8E Q38003193-A7934347-718E-419C-83B5-EF503BA4ADE4 Q38203137-F67139E7-DF08-4E60-A837-A2565D0876C2 Q41517629-7BB8CD3C-DF75-4B2A-BBAC-E7E2F57F4D48 Q41960078-FB81BF65-901F-41BC-AD5A-B2A112481413 Q42147385-BDB50144-A04B-46CA-A894-845A5F6F3867 Q42709886-D14AA2D5-70D4-44C8-B286-1C0C20499157 Q47035963-3598E5D8-4D61-4C9B-AB3E-E21EAC434836

P2860

Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3.

http://www.wikidata.org/entity/Q34467047

description

2005 nî lūn-bûn

@nan

2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3.

@ast

Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3.

@en

Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3.

@nl

type

label

Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3.

@ast

Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3.

@en

Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3.

@nl

prefLabel

Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3.

@ast

Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3.

@en

Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3.

@nl

P1433

Q34467047-520B14E9-869D-4053-A41E-BE51DF88347D

P1476

Q34467047-C9F07C51-BCCC-4D9D-A64C-C373C320D581

P2093

Q34467047-16F811AA-6F1B-41F3-9307-F17AE93F1CF8

Q34467047-50060D1E-2B3B-46BD-814C-70CB6B377282

Q34467047-7D1B15B8-FB8C-4D31-86A6-30758EDFEA9C

Q34467047-CDEBE1C4-EC47-4689-BDE6-BF824EDEA637

Q34467047-FC4C0136-3BA8-4025-A142-14B16764B3FF

P304

Q34467047-EB738E07-65D6-4C10-9C6E-2A14CB9E68DB

P31

Q34467047-4837CB41-8384-4679-A48D-B3CD938A26C4

P356

Q34467047-8280DD87-FEB2-4875-AB91-490C4771F803

P407

Q34467047-3F9EA1F5-0375-4E08-A68E-09A1F7BEEE80

P433

Q34467047-7473FC9D-1D04-4D63-8383-85BFC47FA026

P478

Q34467047-3DF771A6-BD61-4FA0-8F1C-EB9BD722489B

P50

Q34467047-7097E543-622C-4613-92F1-3900C0713008

Q34467047-83790216-9980-4EA8-9E31-BC3309116E12

P577

Q34467047-B2115CD5-7461-490E-8A9C-400494F7DF8A

P698

Q34467047-A568A24A-F6AA-40D0-8E48-73E57D867B6B

P356

01.NEU.0000180811.56157.E1

P1433

P1476

Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3.

@en

P2093

Ali K Ozturk

http://www.w3.org/2001/XMLSchema#string

Bulent Guclu

http://www.w3.org/2001/XMLSchema#string

Dana Shin

http://www.w3.org/2001/XMLSchema#string

Katie L Pricola

http://www.w3.org/2001/XMLSchema#string

Murat Gunel

http://www.w3.org/2001/XMLSchema#string

P304

1008-1013

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1227/01.NEU.0000180811.56157.E1

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

57

http://www.w3.org/2001/XMLSchema#string

P50

P577

2005-11-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

16284570

http://www.w3.org/2001/XMLSchema#string