Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
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Mitochondria: A Therapeutic Target for Parkinson's Disease?Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer's DiseaseA mitochondrial division inhibitor, Mdivi-1, inhibits mitochondrial fragmentation and attenuates kainic acid-induced hippocampal cell deathDRP1 inhibition rescues retinal ganglion cells and their axons by preserving mitochondrial integrity in a mouse model of glaucoma.Inhibition of Drp1 hyper-activation is protective in animal models of experimental multiple sclerosis.Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases.A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division.Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson's disease.Exogenous expression of Drp1 plays neuroprotective roles in the Alzheimer's disease in the Aβ42 transgenic Drosophila model.HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders.Altered Mitochondrial Dynamics and TBI Pathophysiology.Novel targets for mitochondrial medicine.Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTPDrp1-Dependent Mitochondrial Fission Plays Critical Roles in Physiological and Pathological Progresses in Mammals.The Parkinson Disease Mitochondrial Hypothesis: Where Are We at?Fusion or Fission: The Destiny of Mitochondria In Traumatic Brain Injury of Different Severities.Water-Soluble Coenzyme Q10 Reduces Rotenone-Induced Mitochondrial Fission.A conserved retromer sorting motif is essential for mitochondrial DLP1 recycling by VPS35 in Parkinson's disease model.Neuroprotective Effects of Loganin on MPTP-Induced Parkinson's Disease Mice: Neurochemistry, Glial Reaction and Autophagy Studies.The mitochondrial kinase PINK1: functions beyond mitophagy.Mitochondrial fission and fusion in secondary brain damage after CNS insults.Mitochondrial dynamics in neuronal injury, development and plasticity.Fibroblast Biomarkers of Sporadic Parkinson's Disease and LRRK2 Kinase Inhibition.Mitochondrial division inhibitor-1 is neuroprotective in the A53T-α-synuclein rat model of Parkinson's disease.CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling.Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stressFrom smoking guns to footprints: mining for critical events of toxicity pathways in transcriptome data.PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer's disease.The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species.c-Abl-mediated Drp1 phosphorylation promotes oxidative stress-induced mitochondrial fragmentation and neuronal cell death.Vps13D Encodes a Ubiquitin-Binding Protein that Is Required for the Regulation of Mitochondrial Size and Clearance.Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model.Regioselective plasmonic nano-assemblies for bimodal sub-femtomolar dopamine detection.Mitochondrial Targeting in Neurodegeneration: A Heme PerspectiveMetabolic Targeting of Breast Cancer Cells With the 2-Deoxy-D-Glucose and the Mitochondrial Bioenergetics Inhibitor MDIVI-1
P2860
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P2860
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
@ast
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
@en
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
@nl
type
label
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
@ast
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
@en
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
@nl
prefLabel
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
@ast
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
@en
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
@nl
P2860
P50
P356
P1476
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
@en
P2860
P2888
P356
10.1038/NCOMMS6244
P4011
bd60d3f466bcf4542683a45bda7f3af2be6a0d73
P407
P577
2014-11-05T00:00:00Z
P5875
P6179
1028664187