Developing novel oncolytic adenoviruses through bioselection - Wikidata - awgldk - TriplyDB

Developing novel oncolytic adenoviruses through bioselection

Developing novel oncolytic adenoviruses through bioselection

http://www.wikidata.org/entity/Q34471952

about

Directed evolution generates a novel oncolytic virus for the treatment of colon cancer Experimental evolution of an oncolytic vesicular stomatitis virus with increased selectivity for p53-deficient cells.Replication and virus-induced transcriptome of HAdV-5 in normal host cells versus cancer cells--differences of relevance for adenoviral oncolysis.Genetic identification of adenovirus type 5 genes that influence viral spread.Species D human adenovirus type 9 exhibits better virus-spread ability for antitumor efficacy among alternative serotypes.Increasing the efficacy of oncolytic adenovirus vectors Thermostability/infectivity defect caused by deletion of the core protein V gene in human adenovirus type 5 is rescued by thermo-selectable mutations in the core protein X precursor.Herpes simplex virus 1 (HSV-1) for cancer treatment.Adenovirus with DNA Packaging Gene Mutations Increased Virus Release.Oncolytic (replication-competent) adenoviruses as anticancer agents.The combination of i-leader truncation and gemcitabine improves oncolytic adenovirus efficacy in an immunocompetent model.A cathepsin-cleavage site between the adenovirus capsid protein IX and a tumor-targeting ligand improves targeted transduction.Truncating the i-leader open reading frame enhances release of human adenovirus type 5 in glioma cells.Directed adenovirus evolution using engineered mutator viral polymerases.Verapamil enhances the antitumoral efficacy of oncolytic adenoviruses.Adenovirus i-leader truncation bioselected against cancer-associated fibroblasts to overcome tumor stromal barriers.Oncolytic viruses: the power of directed evolution.Development of an Oncolytic Adenovirus with Enhanced Spread Ability through Repeated UV Irradiation and Cancer Selection

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Developing novel oncolytic adenoviruses through bioselection

http://www.wikidata.org/entity/Q34471952

description

2003 nî lūn-bûn

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2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2003 թվականի փետրվարին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Developing novel oncolytic adenoviruses through bioselection

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Developing novel oncolytic adenoviruses through bioselection

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Developing novel oncolytic adenoviruses through bioselection

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type

label

Developing novel oncolytic adenoviruses through bioselection

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Developing novel oncolytic adenoviruses through bioselection

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Developing novel oncolytic adenoviruses through bioselection

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prefLabel

Developing novel oncolytic adenoviruses through bioselection

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Developing novel oncolytic adenoviruses through bioselection

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Developing novel oncolytic adenoviruses through bioselection

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JVI.77.4.2640-2650.2003

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Journal of Virology

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Developing novel oncolytic adenoviruses through bioselection

@en

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Adam Sampson-Johannes

http://www.w3.org/2001/XMLSchema#string

Ali Fattaey

http://www.w3.org/2001/XMLSchema#string

Allan Balmain

http://www.w3.org/2001/XMLSchema#string

Farid Dormishian

http://www.w3.org/2001/XMLSchema#string

Galila Kitzes

http://www.w3.org/2001/XMLSchema#string

Jenny Holt

http://www.w3.org/2001/XMLSchema#string

Josh Watanabe

http://www.w3.org/2001/XMLSchema#string

Lynda Hawkins

http://www.w3.org/2001/XMLSchema#string

Terry Hermiston

http://www.w3.org/2001/XMLSchema#string

Thomas Dubensky

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Evolution of hepatitis C virus quasispecies in hypervariable region 1 and the putative interferon sensitivity-determining region during interferon therapy and natural infection.

Molecular breeding of viruses.

Antitumor synergy of CV787, a prostate cancer-specific adenovirus, and paclitaxel and docetaxel.

HIV-1 evolution under pressure of protease inhibitors: climbing the stairs of viral fitness.

p53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication.

Conditionally replicating herpes vectors for cancer therapy.

Gene delivery from replication-selective viruses: arming guided missiles in the war against cancer.

Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial.

Replicative adenoviruses for cancer therapy.

Interactions between adenovirus proteins and the p53 pathway: the development of ONYX-015.

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2640-2650

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scholarly article

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10.1128/JVI.77.4.2640-2650.2003

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4

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2003-02-01T00:00:00Z

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12552003

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oncolytic virus

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141112

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