L-carnitine is an endogenous HDAC inhibitor selectively inhibiting cancer cell growth in vivo and in vitro.
about
SANIST: a rapid mass spectrometric SACI/ESI data acquisition and elaboration platform for verifying potential candidate biomarkersA novel proteasome inhibitor suppresses tumor growth via targeting both 19S proteasome deubiquitinases and 20S proteolytic peptidases.Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growthHDAC inhibitor L-carnitine and proteasome inhibitor bortezomib synergistically exert anti-tumor activity in vitro and in vivoAnti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanismsIntracellular ATP concentration contributes to the cytotoxic and cytoprotective effects of adenosineL-carnitine prevents progression of non-alcoholic steatohepatitis in a mouse model with upregulation of mitochondrial pathway.Effects of acetaldehyde and L-carnitine on morphology and enzyme activity of myocardial mitochondria in rats.Survival of primary, but not of cancer cells after combined Plk1-HDAC inhibitionTwo clinical drugs deubiquitinase inhibitor auranofin and aldehyde dehydrogenase inhibitor disulfiram trigger synergistic anti-tumor effects in vitro and in vivo.L-carnitine Effectively Induces hTERT Gene Expression of Human Adipose Tissue-derived Mesenchymal Stem Cells Obtained from the Aged Subjects.Use of aerosol route to fabricate positively charged Au/Fe3O4 Janus nanoparticles as multifunctional nanoplatforms.Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy.L-carnitine protects C2C12 cells against mitochondrial superoxide overproduction and cell death.Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases.Proteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor.Potential nephroprotective effects of l-carnitine against drug-induced nephropathy: a review of literature.The growing landscape of lysine acetylation links metabolism and cell signalling.Loss of histone deacetylase Hdac1 disrupts metabolic processes in intestinal epithelial cells.Acetyl-L-Carnitine Prevents Methamphetamine-Induced Structural Damage on Endothelial Cells via ILK-Related MMP-9 Activity.Oxidative stress balance is dysregulated and represents an additional target for treating cholangiocarcinoma.A novel nickel complex works as a proteasomal deubiquitinase inhibitor for cancer therapy.Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination.An Acute Methamphetamine Injection Downregulates the Expression of Several Histone Deacetylases (HDACs) in the Mouse Nucleus Accumbens: Potential Regulatory Role of HDAC2 Expression.
P2860
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P2860
L-carnitine is an endogenous HDAC inhibitor selectively inhibiting cancer cell growth in vivo and in vitro.
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
L-carnitine is an endogenous H ...... l growth in vivo and in vitro.
@ast
L-carnitine is an endogenous H ...... l growth in vivo and in vitro.
@en
L-carnitine is an endogenous H ...... l growth in vivo and in vitro.
@nl
type
label
L-carnitine is an endogenous H ...... l growth in vivo and in vitro.
@ast
L-carnitine is an endogenous H ...... l growth in vivo and in vitro.
@en
L-carnitine is an endogenous H ...... l growth in vivo and in vitro.
@nl
prefLabel
L-carnitine is an endogenous H ...... l growth in vivo and in vitro.
@ast
L-carnitine is an endogenous H ...... l growth in vivo and in vitro.
@en
L-carnitine is an endogenous H ...... l growth in vivo and in vitro.
@nl
P2093
P2860
P1433
P1476
L-carnitine is an endogenous H ...... l growth in vivo and in vitro.
@en
P2093
Change Zhang
Changshan Yang
Chunjiao Liu
Haiping Guo
Hongbiao Huang
Jinbao Liu
Lixia Guan
Ningning Liu
P2860
P304
P356
10.1371/JOURNAL.PONE.0049062
P407
P50
P577
2012-11-05T00:00:00Z