SEL1L a multifaceted protein playing a role in tumor progression. - Wikidata - awgldk - TriplyDB

SEL1L a multifaceted protein playing a role in tumor progression.

SEL1L a multifaceted protein playing a role in tumor progression.

http://www.wikidata.org/entity/Q34473389

about

A SEL1L mutation links a canine progressive early-onset cerebellar ataxia to the endoplasmic reticulum-associated protein degradation (ERAD) machinery SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates Secretion of novel SEL1L endogenous variants is promoted by ER stress/UPR via endosomes and shed vesicles in human cancer cells Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality A stromal gene signature associated with inflammatory breast cancer.Helicobacter pylori evolution: lineage- specific adaptations in homologs of eukaryotic Sel1-like genes sel-11 and cdc-42, two negative modulators of LIN-12/Notch activity in C. elegans Crystallization and preliminary X-ray diffraction analysis of the Sel1-like repeats of SEL1L SEL1L regulates adhesion, proliferation and secretion of insulin by affecting integrin signaling.SEL1L SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy.Selective targeting of proteins within secretory pathway for endoplasmic reticulum-associated degradation.Functional characterization of two secreted SEL1L isoforms capable of exporting unassembled substrate Proteome analysis of Plasmodium falciparum extracellular secretory antigens at asexual blood stages reveals a cohort of proteins with possible roles in immune modulation and signaling.Down-modulation of SEL1L, an unfolded protein response and endoplasmic reticulum-associated degradation protein, sensitizes glioma stem cells to the cytotoxic effect of valproic acid.Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival.Sorting things out through endoplasmic reticulum quality control.Molecular chaperones as therapeutic targets to counteract proteostasis defects.mSEL-1L deficiency affects vasculogenesis and neural stem cell lineage commitment.Missing link between microRNA and prostate cancer.Small molecule antagonist of the bone morphogenetic protein type I receptors suppresses growth and expression of Id1 and Id3 in lung cancer cells expressing Oct4 or nestin Cell and tissue microarray technologies for protein and nucleic acid expression profiling.mSEL-1L (Suppressor/enhancer Lin12-like) protein levels influence murine neural stem cell self-renewal and lineage commitment Genome-wide association study in mice identifies loci affecting liver-related phenotypes including Sel1l influencing serum bile acids.Haploid insufficiency of suppressor enhancer Lin12 1-like (SEL1L) protein predisposes mice to high fat diet-induced hyperglycemia.Melatonin reduces endoplasmic reticulum stress and corneal dystrophy-associated TGFBIp through activation of endoplasmic reticulum-associated protein degradation.HPPD: A newly recognized autosomal dominant disorder involving hypertelorism, preauricular sinus, punctal pits, and deafness mapping to chromosome 14q31.

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P2860

SEL1L a multifaceted protein playing a role in tumor progression.

http://www.wikidata.org/entity/Q34473389

description

2006 nî lūn-bûn

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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հուլիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

@zh-mo

2006年論文

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2006年论文

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name

SEL1L a multifaceted protein playing a role in tumor progression.

@ast

SEL1L a multifaceted protein playing a role in tumor progression.

@en

SEL1L a multifaceted protein playing a role in tumor progression.

@nl

type

label

SEL1L a multifaceted protein playing a role in tumor progression.

@ast

SEL1L a multifaceted protein playing a role in tumor progression.

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SEL1L a multifaceted protein playing a role in tumor progression.

@nl

prefLabel

SEL1L a multifaceted protein playing a role in tumor progression.

@ast

SEL1L a multifaceted protein playing a role in tumor progression.

@en

SEL1L a multifaceted protein playing a role in tumor progression.

@nl

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P1433

Journal of Cellular Physiology

P1476

SEL1L a multifaceted protein playing a role in tumor progression

@en

P2093

Cristina Canton

http://www.w3.org/2001/XMLSchema#string

Ida Biunno

http://www.w3.org/2001/XMLSchema#string

Laura Biagiotti

http://www.w3.org/2001/XMLSchema#string

Massimo Barberis

http://www.w3.org/2001/XMLSchema#string

Stefano Ferrero

http://www.w3.org/2001/XMLSchema#string

Sylvie Ménard

http://www.w3.org/2001/XMLSchema#string

P2860

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment

Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule

The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions.

Control of pancreas and liver gene expression by HNF transcription factors

Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

The role of the ubiquitination-proteasome pathway in breast cancer: applying drugs that affect the ubiquitin-proteasome pathway to the therapy of breast cancer

The hairpin structure of the (6)F1(1)F2(2)F2 fragment from human fibronectin enhances gelatin binding.

Notch signaling: cell fate control and signal integration in development

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23-38

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scholarly article

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10.1002/JCP.20574

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P433

1

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P478

208

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Rosaria Orlandi

Serenella M Pupa

Monica Cattaneo

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2006-07-01T00:00:00Z

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P5875

7437305

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P698

16331677

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