Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased susceptibility to excitotoxicity.
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iPSC-Based Models to Unravel Key Pathogenetic Processes Underlying Motor Neuron Disease DevelopmentNeuronal matrix metalloproteinase-9 is a determinant of selective neurodegenerationGene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration.The role of oxidative stress in degeneration of the neuromuscular junction in amyotrophic lateral sclerosisBioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy.Motor neuron vulnerability and resistance in amyotrophic lateral sclerosis.Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS.Inefficient skeletal muscle oxidative function flanks impaired motor neuron recruitment in Amyotrophic Lateral Sclerosis during exercise.Oxidative stress and autophagic alteration in brainstem of SOD1-G93A mouse model of ALS.Identifying the primary site of pathogenesis in amyotrophic lateral sclerosis - vulnerability of lower motor neurons to proximal excitotoxicity.Deterministic HOX patterning in human pluripotent stem cell-derived neuroectodermBrain-computer interface (BCI) evaluation in people with amyotrophic lateral sclerosis.Controversies and priorities in amyotrophic lateral sclerosis.Transcriptional profiling of differentially vulnerable motor neurons at pre-symptomatic stage in the Smn (2b/-) mouse model of spinal muscular atrophy.Mutation screen reveals novel variants and expands the phenotypes associated with DYNC1H1.Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases.Extraocular motoneurons of the adult rat show higher levels of vascular endothelial growth factor and its receptor Flk-1 than other cranial motoneurons.Inducing Chronic Excitotoxicity in the Mouse Spinal Cord to Investigate Lower Motor Neuron Degeneration.Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS.Cross-disease comparison of amyotrophic lateral sclerosis and spinal muscular atrophy reveals conservation of selective vulnerability but differential neuromuscular junction pathology.Investigating cell death mechanisms in amyotrophic lateral sclerosis using transcriptomics.PTEN regulates AMPA receptor-mediated cell viability in iPS-derived motor neurons.Invited review: decoding the pathophysiological mechanisms that underlie RNA dysregulation in neurodegenerative disorders: a review of the current state of the art.Endogenous recovery after brain damage: molecular mechanisms that balance neuronal life/death fate.Inhibitory dysfunction in amyotrophic lateral sclerosis: future therapeutic opportunities.Ocular Motor Nerve Development in the Presence and Absence of Extraocular Muscle.Axons get ahead: Insights into axon guidance and congenital cranial dysinnervation disorders.Dopamine system, cerebellum, and nucleus ruber in fish and mammals.The C9ORF72 GGGGCC expansion forms RNA G-quadruplex inclusions and sequesters hnRNP H to disrupt splicing in ALS brains.ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networksLabel-Free LC-MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral SclerosisSusceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS.Mitochondrial oxidative phosphorylation transcriptome alterations in human amyotrophic lateral sclerosis spinal cord and blood.Amyotrophic lateral sclerosis-A case report and mechanistic review of the association with toluene and other volatile organic compounds.Increased anxiety-like behavior and selective learning impairments are concomitant to loss of hippocampal interneurons in the presymptomatic SOD1(G93A) ALS mouse model.Unraveling the role of motoneuron autophagy in ALS.Sigma-1 Receptor in Motoneuron Disease.Binding loci of RelA-containing nuclear factor-kappaB dimers in promoter regions of PHM1-31 myometrial smooth muscle cells.Advances in motor neurone disease.
P2860
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P2860
Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased susceptibility to excitotoxicity.
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Unravelling the enigma of sele ...... ceptibility to excitotoxicity.
@ast
Unravelling the enigma of sele ...... ceptibility to excitotoxicity.
@en
Unravelling the enigma of sele ...... ceptibility to excitotoxicity.
@nl
type
label
Unravelling the enigma of sele ...... ceptibility to excitotoxicity.
@ast
Unravelling the enigma of sele ...... ceptibility to excitotoxicity.
@en
Unravelling the enigma of sele ...... ceptibility to excitotoxicity.
@nl
prefLabel
Unravelling the enigma of sele ...... ceptibility to excitotoxicity.
@ast
Unravelling the enigma of sele ...... ceptibility to excitotoxicity.
@en
Unravelling the enigma of sele ...... ceptibility to excitotoxicity.
@nl
P2093
P2860
P50
P1476
Unravelling the enigma of sele ...... ceptibility to excitotoxicity.
@en
P2093
Alice Brockington
Elizabeth Wood
Nicolò Fusi
Paul G Ince
Paul R Heath
Stephen B Wharton
P2860
P2888
P304
P356
10.1007/S00401-012-1058-5
P577
2012-11-13T00:00:00Z