Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase
about
Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetaseMultiple Quality Control Pathways Limit Non-protein Amino Acid Use by Yeast Cytoplasmic Phenylalanyl-tRNA Synthetase.Recent Advances in Understanding Amino Acid Sensing Mechanisms that Regulate mTORC1Sestrin2 is a leucine sensor for the mTORC1 pathwaytRNA synthetase: tRNA aminoacylation and beyondSelf-protective responses to norvaline-induced stress in a leucyl-tRNA synthetase editing-deficient yeast strain.A bridge between the aminoacylation and editing domains of leucyl-tRNA synthetase is crucial for its synthetic activityAmino-acid-dependent shift in tRNA synthetase editing mechanisms.In vivo identification of essential nucleotides in tRNALeu to its functions by using a constructed yeast tRNALeu knockout strain.Merging and scoring molecular interactions utilising existing community standards: tools, use-cases and a case study.Modulation of Aminoacylation and Editing Properties of Leucyl-tRNA Synthetase by a Conserved Structural Module.Degenerate connective polypeptide 1 (CP1) domain from human mitochondrial leucyl-tRNA synthetase.Kinetic partitioning between synthetic and editing pathways in class I aminoacyl-tRNA synthetases occurs at both pre-transfer and post-transfer hydrolytic stepsC-terminal Domain of Leucyl-tRNA Synthetase from Pathogenic Candida albicans Recognizes both tRNASer and tRNALeuCrucial role of the C-terminal domain of Mycobacterium tuberculosis leucyl-tRNA synthetase in aminoacylation and editing.The Yin and Yang of tRNA: proper binding of acceptor end determines the catalytic balance of editing and aminoacylation.Sestrin regulation of TORC1: Is Sestrin a leucine sensor?Five conditions commonly used to down-regulate tor complex 1 generate different physiological situations exhibiting distinct requirements and outcomes.Aminoacylation and translational quality control strategy employed by leucyl-tRNA synthetase from a human pathogen with genetic code ambiguityCoexistence of bacterial leucyl-tRNA synthetases with archaeal tRNA binding domains that distinguish tRNA(Leu) in the archaeal mode.Emergence and evolution.Biochemical Basis of Sestrin Physiological Activities.Role of tRNA amino acid-accepting end in aminoacylation and its quality controlMultilevel functional and structural defects induced by two pathogenic mitochondrial tRNA mutations.A naturally occurring nonapeptide functionally compensates for the CP1 domain of leucyl-tRNA synthetase to modulate aminoacylation activity.The Dawn of the Age of Amino Acid Sensors for the mTORC1 Pathway.Identification of two inherited copy number variants in a male with autism supports two-hit and compound heterozygosity models of autism.
P2860
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P2860
Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Modular pathways for editing n ...... plasmic leucyl-tRNA synthetase
@ast
Modular pathways for editing n ...... plasmic leucyl-tRNA synthetase
@en
Modular pathways for editing n ...... plasmic leucyl-tRNA synthetase
@nl
type
label
Modular pathways for editing n ...... plasmic leucyl-tRNA synthetase
@ast
Modular pathways for editing n ...... plasmic leucyl-tRNA synthetase
@en
Modular pathways for editing n ...... plasmic leucyl-tRNA synthetase
@nl
prefLabel
Modular pathways for editing n ...... plasmic leucyl-tRNA synthetase
@ast
Modular pathways for editing n ...... plasmic leucyl-tRNA synthetase
@en
Modular pathways for editing n ...... plasmic leucyl-tRNA synthetase
@nl
P2093
P2860
P356
P1476
Modular pathways for editing n ...... plasmic leucyl-tRNA synthetase
@en
P2093
En-Duo Wang
Gilbert Eriani
Jing-Jing Ma
Qing-Hua Hu
P2860
P304
P356
10.1093/NAR/GKQ763
P407
P577
2010-08-30T00:00:00Z